View in EDS

Explainable machine learning identifies features and thresholds predictive of immunotherapy response.

Saved in:
Bibliographic Details
Title: Explainable machine learning identifies features and thresholds predictive of immunotherapy response.
Authors: Tran KA; Cancer Program, QIMR Berghofer Medical Research Institute, 300 Herston Road, Brisbane, Australia. khoa.tran@qimrb.edu.au.; School of Biomedical Sciences, Queensland University of Technology (QUT), Brisbane, Australia. khoa.tran@qimrb.edu.au., Addala V; Cancer Program, QIMR Berghofer Medical Research Institute, 300 Herston Road, Brisbane, Australia., Koufariotis LT; Cancer Program, QIMR Berghofer Medical Research Institute, 300 Herston Road, Brisbane, Australia., Zhang J; Cancer Program, QIMR Berghofer Medical Research Institute, 300 Herston Road, Brisbane, Australia., Wood S; Cancer Program, QIMR Berghofer Medical Research Institute, 300 Herston Road, Brisbane, Australia., Leonard C; Cancer Program, QIMR Berghofer Medical Research Institute, 300 Herston Road, Brisbane, Australia., Hoeijmakers LL; Department of Medical Oncology, Netherlands Cancer Institute, Amsterdam, The Netherlands., Blank CU; Department of Medical Oncology, Netherlands Cancer Institute, Amsterdam, The Netherlands.; Department of Medical Oncology, Leiden University Medical Center, Leiden, The Netherlands., Crispin-Ortuzar M; Department of Oncology, University of Cambridge, Cambridge, UK.; Cancer Research UK Cambridge Centre, University of Cambridge, Cambridge, UK., Williams ED; School of Biomedical Sciences, Queensland University of Technology (QUT), Brisbane, Australia.; Australian Prostate Cancer Research Centre - Queensland (APCRC-Q) and Queensland Bladder Cancer Initiative (QBCI), Brisbane, Australia.; Centre for Genomics and Personalised Health, Queensland University of Technology (QUT), Brisbane, QLD, Australia., Kondrashova O; Cancer Program, QIMR Berghofer Medical Research Institute, 300 Herston Road, Brisbane, Australia.; School of Biomedical Sciences, Queensland University of Technology (QUT), Brisbane, Australia., Pearson JV; Cancer Program, QIMR Berghofer Medical Research Institute, 300 Herston Road, Brisbane, Australia., Waddell N; Cancer Program, QIMR Berghofer Medical Research Institute, 300 Herston Road, Brisbane, Australia. nic.waddell@qimrberghofer.edu.au.; School of Biomedical Sciences, Queensland University of Technology (QUT), Brisbane, Australia. nic.waddell@qimrberghofer.edu.au.
Source: Scientific reports [Sci Rep] 2026 May 23. Date of Electronic Publication: 2026 May 23.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 42177174
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Explainable machine learning identifies features and thresholds predictive of immunotherapy response.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Tran+KA%22">Tran KA</searchLink>; Cancer Program, QIMR Berghofer Medical Research Institute, 300 Herston Road, Brisbane, Australia. khoa.tran@qimrb.edu.au.; School of Biomedical Sciences, Queensland University of Technology (QUT), Brisbane, Australia. khoa.tran@qimrb.edu.au.<br /><searchLink fieldCode="AU" term="%22Addala+V%22">Addala V</searchLink>; Cancer Program, QIMR Berghofer Medical Research Institute, 300 Herston Road, Brisbane, Australia.<br /><searchLink fieldCode="AU" term="%22Koufariotis+LT%22">Koufariotis LT</searchLink>; Cancer Program, QIMR Berghofer Medical Research Institute, 300 Herston Road, Brisbane, Australia.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; Cancer Program, QIMR Berghofer Medical Research Institute, 300 Herston Road, Brisbane, Australia.<br /><searchLink fieldCode="AU" term="%22Wood+S%22">Wood S</searchLink>; Cancer Program, QIMR Berghofer Medical Research Institute, 300 Herston Road, Brisbane, Australia.<br /><searchLink fieldCode="AU" term="%22Leonard+C%22">Leonard C</searchLink>; Cancer Program, QIMR Berghofer Medical Research Institute, 300 Herston Road, Brisbane, Australia.<br /><searchLink fieldCode="AU" term="%22Hoeijmakers+LL%22">Hoeijmakers LL</searchLink>; Department of Medical Oncology, Netherlands Cancer Institute, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Blank+CU%22">Blank CU</searchLink>; Department of Medical Oncology, Netherlands Cancer Institute, Amsterdam, The Netherlands.; Department of Medical Oncology, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Crispin-Ortuzar+M%22">Crispin-Ortuzar M</searchLink>; Department of Oncology, University of Cambridge, Cambridge, UK.; Cancer Research UK Cambridge Centre, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Williams+ED%22">Williams ED</searchLink>; School of Biomedical Sciences, Queensland University of Technology (QUT), Brisbane, Australia.; Australian Prostate Cancer Research Centre - Queensland (APCRC-Q) and Queensland Bladder Cancer Initiative (QBCI), Brisbane, Australia.; Centre for Genomics and Personalised Health, Queensland University of Technology (QUT), Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Kondrashova+O%22">Kondrashova O</searchLink>; Cancer Program, QIMR Berghofer Medical Research Institute, 300 Herston Road, Brisbane, Australia.; School of Biomedical Sciences, Queensland University of Technology (QUT), Brisbane, Australia.<br /><searchLink fieldCode="AU" term="%22Pearson+JV%22">Pearson JV</searchLink>; Cancer Program, QIMR Berghofer Medical Research Institute, 300 Herston Road, Brisbane, Australia.<br /><searchLink fieldCode="AU" term="%22Waddell+N%22">Waddell N</searchLink>; Cancer Program, QIMR Berghofer Medical Research Institute, 300 Herston Road, Brisbane, Australia. nic.waddell@qimrberghofer.edu.au.; School of Biomedical Sciences, Queensland University of Technology (QUT), Brisbane, Australia. nic.waddell@qimrberghofer.edu.au.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101563288%22">Scientific reports</searchLink> [Sci Rep] 2026 May 23. <i>Date of Electronic Publication: </i>2026 May 23.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101563288 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2045-2322 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220452322%22">20452322 </searchLink><i>NLM ISO Abbreviation: </i>Sci Rep <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42177174
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/s41598-026-47752-8
    Languages:
      – Code: eng
        Text: English
    Titles:
      – TitleFull: Explainable machine learning identifies features and thresholds predictive of immunotherapy response.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Tran KA
      – PersonEntity:
          Name:
            NameFull: Addala V
      – PersonEntity:
          Name:
            NameFull: Koufariotis LT
      – PersonEntity:
          Name:
            NameFull: Zhang J
      – PersonEntity:
          Name:
            NameFull: Wood S
      – PersonEntity:
          Name:
            NameFull: Leonard C
      – PersonEntity:
          Name:
            NameFull: Hoeijmakers LL
      – PersonEntity:
          Name:
            NameFull: Blank CU
      – PersonEntity:
          Name:
            NameFull: Crispin-Ortuzar M
      – PersonEntity:
          Name:
            NameFull: Williams ED
      – PersonEntity:
          Name:
            NameFull: Kondrashova O
      – PersonEntity:
          Name:
            NameFull: Pearson JV
      – PersonEntity:
          Name:
            NameFull: Waddell N
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 23
              M: 05
              Text: 2026 May 23
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 2045-2322
          Titles:
            – TitleFull: Scientific reports
              Type: main
ResultId 1