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RBM20 isoform regulation by independent transcription start sites adapts alternative splicing in development and disease.

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Title: RBM20 isoform regulation by independent transcription start sites adapts alternative splicing in development and disease.
Authors: Radke MH; Translational Cardiology and Functional Genomics, Max Delbrück Center for Molecular Medicine, Berlin, Germany.; German Center for Cardiovascular Research (DZHK) partner site Berlin, Berlin, Germany., Badillo Lisakowski V; Translational Cardiology and Functional Genomics, Max Delbrück Center for Molecular Medicine, Berlin, Germany.; German Center for Cardiovascular Research (DZHK) partner site Berlin, Berlin, Germany., Meinke S; Translational Cardiology and Functional Genomics, Max Delbrück Center for Molecular Medicine, Berlin, Germany.; German Center for Cardiovascular Research (DZHK) partner site Berlin, Berlin, Germany., Britto-Borges T; Section of Bioinformatics and Systems Cardiology, Klaus Tschira Institute for Integrative Computational Cardiology and Department of Internal Medicine III, University Hospital Heidelberg, Heidelberg, Germany.; German Center for Cardiovascular Research (DZHK) partner site Heidelberg/Mannheim, Heidelberg, Germany., Schneider-Lunitz V; Genetics and Genomics of Cardiovascular Diseases, Max Delbrück Center for Molecular Medicine, Berlin, Germany., Hummel O; Genetics and Genomics of Cardiovascular Diseases, Max Delbrück Center for Molecular Medicine, Berlin, Germany., van Heesch S; Genetics and Genomics of Cardiovascular Diseases, Max Delbrück Center for Molecular Medicine, Berlin, Germany.; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.; Oncode Institute, Utrecht, the Netherlands., Ruiz Orera J; Genetics and Genomics of Cardiovascular Diseases, Max Delbrück Center for Molecular Medicine, Berlin, Germany., Hubner N; German Center for Cardiovascular Research (DZHK) partner site Berlin, Berlin, Germany.; Genetics and Genomics of Cardiovascular Diseases, Max Delbrück Center for Molecular Medicine, Berlin, Germany.; Helmholtz-Institute for Translational AngioCardioScience (HI-TAC) of the Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) at Heidelberg University, Heidelberg, Germany.; Charité Universitätsmedizin, Berlin, Germany., Granzier H; Department of Cellular and Molecular Medicine, University of Arizona, Tucson, AZ, USA., Dieterich C; Section of Bioinformatics and Systems Cardiology, Klaus Tschira Institute for Integrative Computational Cardiology and Department of Internal Medicine III, University Hospital Heidelberg, Heidelberg, Germany.; German Center for Cardiovascular Research (DZHK) partner site Heidelberg/Mannheim, Heidelberg, Germany., Gotthardt M; Translational Cardiology and Functional Genomics, Max Delbrück Center for Molecular Medicine, Berlin, Germany. gotthardt@mdc-berlin.de.; German Center for Cardiovascular Research (DZHK) partner site Berlin, Berlin, Germany. gotthardt@mdc-berlin.de.; Charité Universitätsmedizin, Berlin, Germany. gotthardt@mdc-berlin.de.
Source: Nature communications [Nat Commun] 2026 May 23; Vol. 17 (1). Date of Electronic Publication: 2026 May 23.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: RBM20 isoform regulation by independent transcription start sites adapts alternative splicing in development and disease.
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  Data: <searchLink fieldCode="AU" term="%22Radke+MH%22">Radke MH</searchLink>; Translational Cardiology and Functional Genomics, Max Delbrück Center for Molecular Medicine, Berlin, Germany.; German Center for Cardiovascular Research (DZHK) partner site Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Badillo+Lisakowski+V%22">Badillo Lisakowski V</searchLink>; Translational Cardiology and Functional Genomics, Max Delbrück Center for Molecular Medicine, Berlin, Germany.; German Center for Cardiovascular Research (DZHK) partner site Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Meinke+S%22">Meinke S</searchLink>; Translational Cardiology and Functional Genomics, Max Delbrück Center for Molecular Medicine, Berlin, Germany.; German Center for Cardiovascular Research (DZHK) partner site Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Britto-Borges+T%22">Britto-Borges T</searchLink>; Section of Bioinformatics and Systems Cardiology, Klaus Tschira Institute for Integrative Computational Cardiology and Department of Internal Medicine III, University Hospital Heidelberg, Heidelberg, Germany.; German Center for Cardiovascular Research (DZHK) partner site Heidelberg/Mannheim, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Schneider-Lunitz+V%22">Schneider-Lunitz V</searchLink>; Genetics and Genomics of Cardiovascular Diseases, Max Delbrück Center for Molecular Medicine, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Hummel+O%22">Hummel O</searchLink>; Genetics and Genomics of Cardiovascular Diseases, Max Delbrück Center for Molecular Medicine, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22van+Heesch+S%22">van Heesch S</searchLink>; Genetics and Genomics of Cardiovascular Diseases, Max Delbrück Center for Molecular Medicine, Berlin, Germany.; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.; Oncode Institute, Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Ruiz+Orera+J%22">Ruiz Orera J</searchLink>; Genetics and Genomics of Cardiovascular Diseases, Max Delbrück Center for Molecular Medicine, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Hubner+N%22">Hubner N</searchLink>; German Center for Cardiovascular Research (DZHK) partner site Berlin, Berlin, Germany.; Genetics and Genomics of Cardiovascular Diseases, Max Delbrück Center for Molecular Medicine, Berlin, Germany.; Helmholtz-Institute for Translational AngioCardioScience (HI-TAC) of the Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) at Heidelberg University, Heidelberg, Germany.; Charité Universitätsmedizin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Granzier+H%22">Granzier H</searchLink>; Department of Cellular and Molecular Medicine, University of Arizona, Tucson, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Dieterich+C%22">Dieterich C</searchLink>; Section of Bioinformatics and Systems Cardiology, Klaus Tschira Institute for Integrative Computational Cardiology and Department of Internal Medicine III, University Hospital Heidelberg, Heidelberg, Germany.; German Center for Cardiovascular Research (DZHK) partner site Heidelberg/Mannheim, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Gotthardt+M%22">Gotthardt M</searchLink>; Translational Cardiology and Functional Genomics, Max Delbrück Center for Molecular Medicine, Berlin, Germany. gotthardt@mdc-berlin.de.; German Center for Cardiovascular Research (DZHK) partner site Berlin, Berlin, Germany. gotthardt@mdc-berlin.de.; Charité Universitätsmedizin, Berlin, Germany. gotthardt@mdc-berlin.de.
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