The CHK1 inhibitor Prexasertib is effective against in vitro models of aggressive thyroid carcinomas with defective p53 function.
Saved in:
| Title: | The CHK1 inhibitor Prexasertib is effective against in vitro models of aggressive thyroid carcinomas with defective p53 function. |
|---|---|
| Authors: | Manzo A; Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy., Grassi ES; Department of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano IRCCS, Milan, Italy., Borghi MO; Immunorheumatology Research Laboratory, IRCCS Istituto Auxologico Italiano, Milan, Italy.; Dipartimento di Scienze Cliniche e di Comunità, Dipartimento di Eccellenza 2023-2027, University of Milan, Milan, Italy., Colombo C; Department of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano IRCCS, Milan, Italy.; Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy., Persani L; Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy.; Department of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano IRCCS, Milan, Italy., Cirello V; Department of Endocrine and Metabolic Diseases, Istituto Auxologico Italiano IRCCS, Milan, Italy.; Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy. |
| Source: | Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2026 May 08; Vol. 17, pp. 1743111. Date of Electronic Publication: 2026 May 08 (Print Publication: 2026). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101555782 Publication Model: eCollection Cited Medium: Print ISSN: 1664-2392 (Print) Linking ISSN: 16642392 NLM ISO Abbreviation: Front Endocrinol (Lausanne) Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
|
Full text is not displayed to guests.
Login for full access.
|
|
| ISSN: | 1664-2392 |
|---|---|
| DOI: | 10.3389/fendo.2026.1743111 |
