Targeting PIP5K ameliorates hepatic cancer by inhibiting PI3K/AKT and the autophagy mechanism and enhancing ROS-mediated apoptosis.
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| Title: | Targeting PIP5K ameliorates hepatic cancer by inhibiting PI3K/AKT and the autophagy mechanism and enhancing ROS-mediated apoptosis. |
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| Authors: | Shantanu PA; Department of Pharmacology & Toxicology, National Institute of Pharmaceutical Education and Research Guwahati, Guwahati, Assam, India., Rajdev B; Department of Pharmacology & Toxicology, National Institute of Pharmaceutical Education and Research Guwahati, Guwahati, Assam, India., Syamprasad NP; Department of Pharmacology & Toxicology, National Institute of Pharmaceutical Education and Research Guwahati, Guwahati, Assam, India., Gangasani JK; Department of Pharmacology & Toxicology, National Institute of Pharmaceutical Education and Research Guwahati, Guwahati, Assam, India., Mandal A; Department of Pharmacology & Toxicology, National Institute of Pharmaceutical Education and Research Guwahati, Guwahati, Assam, India., Panda SR; Department of Pharmacology & Toxicology, National Institute of Pharmaceutical Education and Research Guwahati, Guwahati, Assam, India., Sistla R; Medicinal Chemistry and Pharmacology Division, CSIR-Indian Institute of Chemical Technology (IICT), Hyderabad, Telangana, India., Andugulapati SB; Medicinal Chemistry and Pharmacology Division, CSIR-Indian Institute of Chemical Technology (IICT), Hyderabad, Telangana, India., Sarin SK; Liver Physiology and Vascular Biology Lab, Department of Molecular and Cellular Medicine, Institute of Liver and Biliary Sciences (ILBS), New Delhi, India., Tripathi DM; Liver Physiology and Vascular Biology Lab, Department of Molecular and Cellular Medicine, Institute of Liver and Biliary Sciences (ILBS), New Delhi, India., Naidu VGM; Department of Pharmacology & Toxicology, National Institute of Pharmaceutical Education and Research Guwahati, Guwahati, Assam, India. |
| Source: | Frontiers in pharmacology [Front Pharmacol] 2026 May 08; Vol. 17, pp. 1791462. Date of Electronic Publication: 2026 May 08 (Print Publication: 2026). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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