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Aberrant CD4+ T cell refeeding response impairs neuro-immune crosstalk in Parkinson's disease.

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Title: Aberrant CD4+ T cell refeeding response impairs neuro-immune crosstalk in Parkinson's disease.
Authors: Austin-Muttitt K; Molecular Neurobiology, Institute of Life Science, Swansea University Medical School, Swansea, Wales, UK., David BR; Molecular Neurobiology, Institute of Life Science, Swansea University Medical School, Swansea, Wales, UK., Sassi M; Molecular Neurobiology, Institute of Life Science, Swansea University Medical School, Swansea, Wales, UK., Agarwal R; Laboratory of Genetics, Salk Institute for Biological Sciences, La Jolla, San Diego, CA, USA., Sabedot TS; Laboratory of Genetics, Salk Institute for Biological Sciences, La Jolla, San Diego, CA, USA., Jones JR; Laboratory of Genetics, Salk Institute for Biological Sciences, La Jolla, San Diego, CA, USA., Cuoco MS; Laboratory of Genetics, Salk Institute for Biological Sciences, La Jolla, San Diego, CA, USA., Jenkins BJ; Institute of Life Science, Swansea University Medical School, Swansea, Wales, UK., Roberts LD; Molecular Neurobiology, Institute of Life Science, Swansea University Medical School, Swansea, Wales, UK., Harris L; Molecular Neurobiology, Institute of Life Science, Swansea University Medical School, Swansea, Wales, UK., Kieronczyk N; Molecular Neurobiology, Institute of Life Science, Swansea University Medical School, Swansea, Wales, UK., Han G; Molecular Neurobiology, Institute of Life Science, Swansea University Medical School, Swansea, Wales, UK., Hitchings MD; Institute of Life Science, Swansea University Medical School, Swansea, Wales, UK., Donaghy PC; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, England, UK.; NIHR Newcastle Biomedical Research Centre, Newcastle University, Newcastle upon Tyne, England, UK., Yarnall AJ; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, England, UK.; NIHR Newcastle Biomedical Research Centre, Newcastle University, Newcastle upon Tyne, England, UK.; Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, England, UK., Thornton CA; Institute of Life Science, Swansea University Medical School, Swansea, Wales, UK., Mohamed B; University Hospital Llandough, Cardiff and Vale University Health Board, Penarth, Wales, UK., Morgan AH; Molecular Neurobiology, Institute of Life Science, Swansea University Medical School, Swansea, Wales, UK., Thomas F; Parkinson's Clinic, Gorseinon Hospital, Swansea Bay University Health Board, Swansea, Wales, UK., Jones N; Institute of Life Science, Swansea University Medical School, Swansea, Wales, UK., Gage FH; Laboratory of Genetics, Salk Institute for Biological Sciences, La Jolla, San Diego, CA, USA., Davies JS; Molecular Neurobiology, Institute of Life Science, Swansea University Medical School, Swansea, Wales, UK.; Laboratory of Genetics, Salk Institute for Biological Sciences, La Jolla, San Diego, CA, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 May 11. Date of Electronic Publication: 2026 May 11.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Aberrant CD4<superscript>+</superscript> T cell refeeding response impairs neuro-immune crosstalk in Parkinson's disease.
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  Data: <searchLink fieldCode="AU" term="%22Austin-Muttitt+K%22">Austin-Muttitt K</searchLink>; Molecular Neurobiology, Institute of Life Science, Swansea University Medical School, Swansea, Wales, UK.<br /><searchLink fieldCode="AU" term="%22David+BR%22">David BR</searchLink>; Molecular Neurobiology, Institute of Life Science, Swansea University Medical School, Swansea, Wales, UK.<br /><searchLink fieldCode="AU" term="%22Sassi+M%22">Sassi M</searchLink>; Molecular Neurobiology, Institute of Life Science, Swansea University Medical School, Swansea, Wales, UK.<br /><searchLink fieldCode="AU" term="%22Agarwal+R%22">Agarwal R</searchLink>; Laboratory of Genetics, Salk Institute for Biological Sciences, La Jolla, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Sabedot+TS%22">Sabedot TS</searchLink>; Laboratory of Genetics, Salk Institute for Biological Sciences, La Jolla, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Jones+JR%22">Jones JR</searchLink>; Laboratory of Genetics, Salk Institute for Biological Sciences, La Jolla, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Cuoco+MS%22">Cuoco MS</searchLink>; Laboratory of Genetics, Salk Institute for Biological Sciences, La Jolla, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Jenkins+BJ%22">Jenkins BJ</searchLink>; Institute of Life Science, Swansea University Medical School, Swansea, Wales, UK.<br /><searchLink fieldCode="AU" term="%22Roberts+LD%22">Roberts LD</searchLink>; Molecular Neurobiology, Institute of Life Science, Swansea University Medical School, Swansea, Wales, UK.<br /><searchLink fieldCode="AU" term="%22Harris+L%22">Harris L</searchLink>; Molecular Neurobiology, Institute of Life Science, Swansea University Medical School, Swansea, Wales, UK.<br /><searchLink fieldCode="AU" term="%22Kieronczyk+N%22">Kieronczyk N</searchLink>; Molecular Neurobiology, Institute of Life Science, Swansea University Medical School, Swansea, Wales, UK.<br /><searchLink fieldCode="AU" term="%22Han+G%22">Han G</searchLink>; Molecular Neurobiology, Institute of Life Science, Swansea University Medical School, Swansea, Wales, UK.<br /><searchLink fieldCode="AU" term="%22Hitchings+MD%22">Hitchings MD</searchLink>; Institute of Life Science, Swansea University Medical School, Swansea, Wales, UK.<br /><searchLink fieldCode="AU" term="%22Donaghy+PC%22">Donaghy PC</searchLink>; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, England, UK.; NIHR Newcastle Biomedical Research Centre, Newcastle University, Newcastle upon Tyne, England, UK.<br /><searchLink fieldCode="AU" term="%22Yarnall+AJ%22">Yarnall AJ</searchLink>; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, England, UK.; NIHR Newcastle Biomedical Research Centre, Newcastle University, Newcastle upon Tyne, England, UK.; Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, England, UK.<br /><searchLink fieldCode="AU" term="%22Thornton+CA%22">Thornton CA</searchLink>; Institute of Life Science, Swansea University Medical School, Swansea, Wales, UK.<br /><searchLink fieldCode="AU" term="%22Mohamed+B%22">Mohamed B</searchLink>; University Hospital Llandough, Cardiff and Vale University Health Board, Penarth, Wales, UK.<br /><searchLink fieldCode="AU" term="%22Morgan+AH%22">Morgan AH</searchLink>; Molecular Neurobiology, Institute of Life Science, Swansea University Medical School, Swansea, Wales, UK.<br /><searchLink fieldCode="AU" term="%22Thomas+F%22">Thomas F</searchLink>; Parkinson's Clinic, Gorseinon Hospital, Swansea Bay University Health Board, Swansea, Wales, UK.<br /><searchLink fieldCode="AU" term="%22Jones+N%22">Jones N</searchLink>; Institute of Life Science, Swansea University Medical School, Swansea, Wales, UK.<br /><searchLink fieldCode="AU" term="%22Gage+FH%22">Gage FH</searchLink>; Laboratory of Genetics, Salk Institute for Biological Sciences, La Jolla, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Davies+JS%22">Davies JS</searchLink>; Molecular Neurobiology, Institute of Life Science, Swansea University Medical School, Swansea, Wales, UK.; Laboratory of Genetics, Salk Institute for Biological Sciences, La Jolla, San Diego, CA, USA.
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  Data: <searchLink fieldCode="JN" term="%22101680187%22">BioRxiv : the preprint server for biology</searchLink> [bioRxiv] 2026 May 11. <i>Date of Electronic Publication: </i>2026 May 11.
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