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Engineered haptoglobin β fusion protein targets myoglobin and ameliorates rhabdomyolysis-associated acute kidney injury.

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Title: Engineered haptoglobin β fusion protein targets myoglobin and ameliorates rhabdomyolysis-associated acute kidney injury.
Authors: Li N; School of Disaster and Emergency Medicine, Tianjin University, Tianjin, China., Wang Y; School of Disaster and Emergency Medicine, Tianjin University, Tianjin, China., Han L; School of Disaster and Emergency Medicine, Tianjin University, Tianjin, China.; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China.; Tianjin Institutes of Health Science, Tianjin, China., Qiao O; School of Disaster and Emergency Medicine, Tianjin University, Tianjin, China., Wang X; School of Disaster and Emergency Medicine, Tianjin University, Tianjin, China., Hao H; School of Disaster and Emergency Medicine, Tianjin University, Tianjin, China., Chen X; School of Disaster and Emergency Medicine, Tianjin University, Tianjin, China., Wang P; Department of Intensive Care Unit, Key Laboratory for Critical Care Medicine of the Ministry of Health, Emergency Medicine Research Institute, Tianjin First Center Hospital, Tianjin, China., Saeed S; School of Disaster and Emergency Medicine, Tianjin University, Tianjin, China., Wang J; School of Disaster and Emergency Medicine, Tianjin University, Tianjin, China., Bao F; School of Disaster and Emergency Medicine, Tianjin University, Tianjin, China., Hou Y; School of Disaster and Emergency Medicine, Tianjin University, Tianjin, China., Zhang L; School of Disaster and Emergency Medicine, Tianjin University, Tianjin, China., Duan X; School of Disaster and Emergency Medicine, Tianjin University, Tianjin, China., Rao S; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China. raoshuquan@ihcams.ac.cn.; Tianjin Institutes of Health Science, Tianjin, China. raoshuquan@ihcams.ac.cn., Gong Y; School of Disaster and Emergency Medicine, Tianjin University, Tianjin, China. gongyanhua@tju.edu.cn.
Source: EMBO molecular medicine [EMBO Mol Med] 2026 Jul; Vol. 18 (7), pp. 2723-2747. Date of Electronic Publication: 2026 May 25.
Publication Type: Journal Article
Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Engineered haptoglobin β fusion protein targets myoglobin and ameliorates rhabdomyolysis-associated acute kidney injury.
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  Data: <searchLink fieldCode="AU" term="%22Li+N%22">Li N</searchLink>; School of Disaster and Emergency Medicine, Tianjin University, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; School of Disaster and Emergency Medicine, Tianjin University, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Han+L%22">Han L</searchLink>; School of Disaster and Emergency Medicine, Tianjin University, Tianjin, China.; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China.; Tianjin Institutes of Health Science, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Qiao+O%22">Qiao O</searchLink>; School of Disaster and Emergency Medicine, Tianjin University, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; School of Disaster and Emergency Medicine, Tianjin University, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Hao+H%22">Hao H</searchLink>; School of Disaster and Emergency Medicine, Tianjin University, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Chen+X%22">Chen X</searchLink>; School of Disaster and Emergency Medicine, Tianjin University, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Wang+P%22">Wang P</searchLink>; Department of Intensive Care Unit, Key Laboratory for Critical Care Medicine of the Ministry of Health, Emergency Medicine Research Institute, Tianjin First Center Hospital, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Saeed+S%22">Saeed S</searchLink>; School of Disaster and Emergency Medicine, Tianjin University, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; School of Disaster and Emergency Medicine, Tianjin University, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Bao+F%22">Bao F</searchLink>; School of Disaster and Emergency Medicine, Tianjin University, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Hou+Y%22">Hou Y</searchLink>; School of Disaster and Emergency Medicine, Tianjin University, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Zhang+L%22">Zhang L</searchLink>; School of Disaster and Emergency Medicine, Tianjin University, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Duan+X%22">Duan X</searchLink>; School of Disaster and Emergency Medicine, Tianjin University, Tianjin, China.<br /><searchLink fieldCode="AU" term="%22Rao+S%22">Rao S</searchLink>; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China. raoshuquan@ihcams.ac.cn.; Tianjin Institutes of Health Science, Tianjin, China. raoshuquan@ihcams.ac.cn.<br /><searchLink fieldCode="AU" term="%22Gong+Y%22">Gong Y</searchLink>; School of Disaster and Emergency Medicine, Tianjin University, Tianjin, China. gongyanhua@tju.edu.cn.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22EMBO+Press%22">EMBO Press </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>101487380 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1757-4684 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217574676%22">17574676 </searchLink><i>NLM ISO Abbreviation: </i>EMBO Mol Med <i>Subsets: </i>MEDLINE
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        Value: 10.1038/s44321-026-00454-0
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        Text: English
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        StartPage: 2723
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            – D: 01
              M: 07
              Text: 2026 Jul
              Type: published
              Y: 2026
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