Is SORL1 a common genetic target across neurodegenerative diseases? A multi-ancestry biobank study.
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| Title: | Is SORL1 a common genetic target across neurodegenerative diseases? A multi-ancestry biobank study. |
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| Authors: | Khani M; Center for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA., Yeboah SN; Center for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA., Cerquera-Cleves C; Department of Neurosciences, Neurology Unit, Hospital Universitario San Ignacio, Bogotá, Colombia.; CHU de Québec Research Center, Axe Neurosciences, Laval University, Québec City, Québec, QC G1V 4G2, Canada., Kedmi A; Center for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA., Bustos BI; Ken and Ruth Davee Department of Neurology and Simpson Querrey Center for Neurogenetics, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA., Grant SM; Center for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA., Can Akerman S; Brain Science Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Akçimen F; Molecular Genetics Section, Laboratory of Neurogenetics, National Institute on Aging, and National Institutes of Health, Bethesda, MD 20892, USA., Lee PS; Center for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA., Reyes-Pérez P; Laboratorio Internacional de Investigación sobre el Genoma Humano, Universidad Nacional Autónoma de México, Campus UNAM 3001, Juriquilla, QRO 76230, México., Lange LM; Molecular Genetics Section, Laboratory of Neurogenetics, National Institute on Aging, and National Institutes of Health, Bethesda, MD 20892, USA., Leonard H; Center for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.; Data Tecnica LLC, Washington, DC 20037, USA., Koretsky MJ; Center for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.; Data Tecnica LLC, Washington, DC 20037, USA., Makarious MB; Center for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.; Data Tecnica LLC, Washington, DC 20037, USA., Schneider Z; Center for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA., Jonson C; Center for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.; Data Tecnica LLC, Washington, DC 20037, USA., Chen PS; Department of Neurology, National Taiwan University Hospital Bei-Hu branch, Taipei 114, Taiwan., Tay YW; Department of Biomedical Science, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia., Rothstein JD; Brain Science Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Lin CH; Department of Neurology, National Taiwan University Hospital, Taipei 100, Taiwan., Lim SY; Division of Neurology, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia., Klein C; Institute of Neurogenetics, University of Lübeck, Lübeck 23538, Germany., Merchant K; Ken and Ruth Davee Department of Neurology and Simpson Querrey Center for Neurogenetics, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA., Mencacci NE; Ken and Ruth Davee Department of Neurology and Simpson Querrey Center for Neurogenetics, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA., Krainc D; Ken and Ruth Davee Department of Neurology and Simpson Querrey Center for Neurogenetics, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA., Cookson MR; Center for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.; Molecular Genetics Section, Laboratory of Neurogenetics, National Institute on Aging, and National Institutes of Health, Bethesda, MD 20892, USA., Singleton A; Global Parkinson's Genetics Program, USA., Bandres-Ciga S; Center for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA. |
| Source: | Brain : a journal of neurology [Brain] 2026 May 26. Date of Electronic Publication: 2026 May 26. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Oxford University Press Country of Publication: England NLM ID: 0372537 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2156 (Electronic) Linking ISSN: 00068950 NLM ISO Abbreviation: Brain Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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