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Distribution of divalent small interfering RNA into neurons of sensory ganglia produces selective, durable knockdown of Nav1.7 and strong analgesia.

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Title: Distribution of divalent small interfering RNA into neurons of sensory ganglia produces selective, durable knockdown of Nav1.7 and strong analgesia.
Authors: Gallant-Behm CL; Atalanta Therapeutics, Inc, Boston, MA, United States., Siemian JN, Tran D, Rook M, Yang C, Wimalanathan K, Zhoba H, Prinzen A, Li M, Lynch T, Omer A, Jagtap S, Rogers KA, Kinberger GA, Yudowski G, Chen Q, Jackson AL, McDonough SI
Source: Pain [Pain] 2026 Aug 01; Vol. 167 (8), pp. 1894-1909. Date of Electronic Publication: 2026 May 20.
Publication Type: Journal Article
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 7508686 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-6623 (Electronic) Linking ISSN: 03043959 NLM ISO Abbreviation: Pain Subsets: MEDLINE
Database: MEDLINE Ultimate
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Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 42187058
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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  Data: Distribution of divalent small interfering RNA into neurons of sensory ganglia produces selective, durable knockdown of Nav1.7 and strong analgesia.
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  Data: <searchLink fieldCode="AU" term="%22Gallant-Behm+CL%22">Gallant-Behm CL</searchLink>; Atalanta Therapeutics, Inc, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Siemian+JN%22">Siemian JN</searchLink><br /><searchLink fieldCode="AU" term="%22Tran+D%22">Tran D</searchLink><br /><searchLink fieldCode="AU" term="%22Rook+M%22">Rook M</searchLink><br /><searchLink fieldCode="AU" term="%22Yang+C%22">Yang C</searchLink><br /><searchLink fieldCode="AU" term="%22Wimalanathan+K%22">Wimalanathan K</searchLink><br /><searchLink fieldCode="AU" term="%22Zhoba+H%22">Zhoba H</searchLink><br /><searchLink fieldCode="AU" term="%22Prinzen+A%22">Prinzen A</searchLink><br /><searchLink fieldCode="AU" term="%22Li+M%22">Li M</searchLink><br /><searchLink fieldCode="AU" term="%22Lynch+T%22">Lynch T</searchLink><br /><searchLink fieldCode="AU" term="%22Omer+A%22">Omer A</searchLink><br /><searchLink fieldCode="AU" term="%22Jagtap+S%22">Jagtap S</searchLink><br /><searchLink fieldCode="AU" term="%22Rogers+KA%22">Rogers KA</searchLink><br /><searchLink fieldCode="AU" term="%22Kinberger+GA%22">Kinberger GA</searchLink><br /><searchLink fieldCode="AU" term="%22Yudowski+G%22">Yudowski G</searchLink><br /><searchLink fieldCode="AU" term="%22Chen+Q%22">Chen Q</searchLink><br /><searchLink fieldCode="AU" term="%22Jackson+AL%22">Jackson AL</searchLink><br /><searchLink fieldCode="AU" term="%22McDonough+SI%22">McDonough SI</searchLink>
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  Data: <searchLink fieldCode="JN" term="%227508686%22">Pain</searchLink> [Pain] 2026 Aug 01; Vol. 167 (8), pp. 1894-1909. <i>Date of Electronic Publication: </i>2026 May 20.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Lippincott+Williams+%26+Wilkins%22">Lippincott Williams & Wilkins </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7508686 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1872-6623 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203043959%22">03043959 </searchLink><i>NLM ISO Abbreviation: </i>Pain <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42187058
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      – Type: doi
        Value: 10.1097/j.pain.0000000000004003
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      – Code: eng
        Text: English
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        StartPage: 1894
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      – TitleFull: Distribution of divalent small interfering RNA into neurons of sensory ganglia produces selective, durable knockdown of Nav1.7 and strong analgesia.
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            – D: 01
              M: 08
              Text: 2026 Aug 01
              Type: published
              Y: 2026
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              Value: 167
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