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Sustainable One-Pot Synthesis of Novel Triazolopyrimidine Derivatives as Selective CDK4 Inhibitors for Breast Cancer Therapy.

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Title: Sustainable One-Pot Synthesis of Novel Triazolopyrimidine Derivatives as Selective CDK4 Inhibitors for Breast Cancer Therapy.
Authors: Elsayed DA; Department of Chemistry, Faculty of Science, Zagazig University, Zagazig, Egypt., Shehab WS; Department of Chemistry, Faculty of Science, Zagazig University, Zagazig, Egypt., Mohamed MM; Viral Media Lab, Egyptian Organization for Biological Products & Vaccines (VACSERA), Giza, Egypt.; Department of Medical Laboratory Techniques, Al-Farahidi University, Baghdad, Iraq., Mesbah AE; Department of Chemistry, Faculty of Science, Mansoura University, Mansoura, Egypt., El-Bassyouni GT; Refractories, Ceramics and Building Materials Department, National Research Centre, Cairo, Egypt., Mousa SM; Inorganic Chemistry Department, National Research Centre, Cairo, Egypt., Abo Elenin OM; Department of Chemistry, Faculty of Science, Zagazig University, Zagazig, Egypt., Assy MG; Department of Chemistry, Faculty of Science, Zagazig University, Zagazig, Egypt., Tantawy ES; Department of Chemistry, Faculty of Science, Zagazig University, Zagazig, Egypt.
Source: Drug development research [Drug Dev Res] 2026 Jun; Vol. 87 (4), pp. e70322.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8204468 Publication Model: Print Cited Medium: Internet ISSN: 1098-2299 (Electronic) Linking ISSN: 02724391 NLM ISO Abbreviation: Drug Dev Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Sustainable One-Pot Synthesis of Novel Triazolopyrimidine Derivatives as Selective CDK4 Inhibitors for Breast Cancer Therapy.
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  Data: <searchLink fieldCode="AU" term="%22Elsayed+DA%22">Elsayed DA</searchLink>; Department of Chemistry, Faculty of Science, Zagazig University, Zagazig, Egypt.<br /><searchLink fieldCode="AU" term="%22Shehab+WS%22">Shehab WS</searchLink>; Department of Chemistry, Faculty of Science, Zagazig University, Zagazig, Egypt.<br /><searchLink fieldCode="AU" term="%22Mohamed+MM%22">Mohamed MM</searchLink>; Viral Media Lab, Egyptian Organization for Biological Products & Vaccines (VACSERA), Giza, Egypt.; Department of Medical Laboratory Techniques, Al-Farahidi University, Baghdad, Iraq.<br /><searchLink fieldCode="AU" term="%22Mesbah+AE%22">Mesbah AE</searchLink>; Department of Chemistry, Faculty of Science, Mansoura University, Mansoura, Egypt.<br /><searchLink fieldCode="AU" term="%22El-Bassyouni+GT%22">El-Bassyouni GT</searchLink>; Refractories, Ceramics and Building Materials Department, National Research Centre, Cairo, Egypt.<br /><searchLink fieldCode="AU" term="%22Mousa+SM%22">Mousa SM</searchLink>; Inorganic Chemistry Department, National Research Centre, Cairo, Egypt.<br /><searchLink fieldCode="AU" term="%22Abo+Elenin+OM%22">Abo Elenin OM</searchLink>; Department of Chemistry, Faculty of Science, Zagazig University, Zagazig, Egypt.<br /><searchLink fieldCode="AU" term="%22Assy+MG%22">Assy MG</searchLink>; Department of Chemistry, Faculty of Science, Zagazig University, Zagazig, Egypt.<br /><searchLink fieldCode="AU" term="%22Tantawy+ES%22">Tantawy ES</searchLink>; Department of Chemistry, Faculty of Science, Zagazig University, Zagazig, Egypt.
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        Value: 10.1002/ddr.70322
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      – TitleFull: Sustainable One-Pot Synthesis of Novel Triazolopyrimidine Derivatives as Selective CDK4 Inhibitors for Breast Cancer Therapy.
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              M: 06
              Text: 2026 Jun
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