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Low Shear Stress Promotes Atherosclerosis by Mediating Pathological Accumulation of Endothelial Lipid Droplets via the KLF4/TFEB/ATP1A1 Axis.

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Title: Low Shear Stress Promotes Atherosclerosis by Mediating Pathological Accumulation of Endothelial Lipid Droplets via the KLF4/TFEB/ATP1A1 Axis.
Authors: Shi Y; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China., Tan YN; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China., Wu LD; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China., Wang LG; Department of Cardiology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, China., Gu Y; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China., Zhou WY; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China., Shao MQ; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China., Zhang JX; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China.
Source: Journal of cardiovascular development and disease [J Cardiovasc Dev Dis] 2026 May 15; Vol. 13 (5). Date of Electronic Publication: 2026 May 15.
Publication Type: Journal Article
Journal Info: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101651414 Publication Model: Electronic Cited Medium: Internet ISSN: 2308-3425 (Electronic) Linking ISSN: 23083425 NLM ISO Abbreviation: J Cardiovasc Dev Dis Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Low Shear Stress Promotes Atherosclerosis by Mediating Pathological Accumulation of Endothelial Lipid Droplets via the KLF4/TFEB/ATP1A1 Axis.
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  Data: <searchLink fieldCode="AU" term="%22Shi+Y%22">Shi Y</searchLink>; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China.<br /><searchLink fieldCode="AU" term="%22Tan+YN%22">Tan YN</searchLink>; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China.<br /><searchLink fieldCode="AU" term="%22Wu+LD%22">Wu LD</searchLink>; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China.<br /><searchLink fieldCode="AU" term="%22Wang+LG%22">Wang LG</searchLink>; Department of Cardiology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, China.<br /><searchLink fieldCode="AU" term="%22Gu+Y%22">Gu Y</searchLink>; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China.<br /><searchLink fieldCode="AU" term="%22Zhou+WY%22">Zhou WY</searchLink>; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China.<br /><searchLink fieldCode="AU" term="%22Shao+MQ%22">Shao MQ</searchLink>; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China.<br /><searchLink fieldCode="AU" term="%22Zhang+JX%22">Zhang JX</searchLink>; Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China.
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  Data: <searchLink fieldCode="JN" term="%22101651414%22">Journal of cardiovascular development and disease</searchLink> [J Cardiovasc Dev Dis] 2026 May 15; Vol. 13 (5). <i>Date of Electronic Publication: </i>2026 May 15.
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        Value: 10.3390/jcdd13050213
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      – TitleFull: Low Shear Stress Promotes Atherosclerosis by Mediating Pathological Accumulation of Endothelial Lipid Droplets via the KLF4/TFEB/ATP1A1 Axis.
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              Text: 2026 May 15
              Type: published
              Y: 2026
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