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Direct Chemical Reprogramming of Human Fibroblasts into Retinal Progenitor-like Cells for Ocular Delivery.

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Title: Direct Chemical Reprogramming of Human Fibroblasts into Retinal Progenitor-like Cells for Ocular Delivery.
Authors: Lee YC; Doctoral Degree Program in Translational Medicine, Tzu Chi University and Academia Sinica, Hualien 970374, Taiwan.; Department of Ophthalmology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien 970473, Taiwan.; Genomics Research Center, Academia Sinica, Taipei 115201, Taiwan., Lai PL; Genomics Research Center, Academia Sinica, Taipei 115201, Taiwan.; Biomedical Translation Research Center, Academia Sinica, Taipei 115201, Taiwan., Lai CY; Genomics Research Center, Academia Sinica, Taipei 115201, Taiwan., Chang FL; Department of Ophthalmology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien 970473, Taiwan., Wu SY; Department of Ophthalmology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien 970473, Taiwan., Lin PY; Genomics Research Center, Academia Sinica, Taipei 115201, Taiwan., Chuang CH; Genomics Research Center, Academia Sinica, Taipei 115201, Taiwan., Chou YX; Genomics Research Center, Academia Sinica, Taipei 115201, Taiwan., Chen ZF; Genomics Research Center, Academia Sinica, Taipei 115201, Taiwan., Wu YC; Genomics Research Center, Academia Sinica, Taipei 115201, Taiwan., Cheng CL; Genomics Research Center, Academia Sinica, Taipei 115201, Taiwan., Lin H; Genomics Research Center, Academia Sinica, Taipei 115201, Taiwan.; Research Center for Applied Sciences, Academia Sinica, Taipei 115201, Taiwan., Ng CH; Genomics Research Center, Academia Sinica, Taipei 115201, Taiwan.; Institute of Molecular and Cellular Biology, National Taiwan University, Taipei 106319, Taiwan., Yang SC; Genomics Research Center, Academia Sinica, Taipei 115201, Taiwan., Lu J; Doctoral Degree Program in Translational Medicine, Tzu Chi University and Academia Sinica, Hualien 970374, Taiwan.; Genomics Research Center, Academia Sinica, Taipei 115201, Taiwan.; Biomedical Translation Research Center, Academia Sinica, Taipei 115201, Taiwan., Tsai RK; Doctoral Degree Program in Translational Medicine, Tzu Chi University and Academia Sinica, Hualien 970374, Taiwan.; Institute of Eye Research, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien 970473, Taiwan.; Institute of Medical Sciences, Tzu Chi University, Hualien 970374, Taiwan.
Source: Journal of functional biomaterials [J Funct Biomater] 2026 May 08; Vol. 17 (5). Date of Electronic Publication: 2026 May 08.
Publication Type: Journal Article
Journal Info: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101570734 Publication Model: Electronic Cited Medium: Print ISSN: 2079-4983 (Print) Linking ISSN: 20794983 NLM ISO Abbreviation: J Funct Biomater Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Direct Chemical Reprogramming of Human Fibroblasts into Retinal Progenitor-like Cells for Ocular Delivery.
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  Data: <searchLink fieldCode="AU" term="%22Lee+YC%22">Lee YC</searchLink>; Doctoral Degree Program in Translational Medicine, Tzu Chi University and Academia Sinica, Hualien 970374, Taiwan.; Department of Ophthalmology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien 970473, Taiwan.; Genomics Research Center, Academia Sinica, Taipei 115201, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lai+PL%22">Lai PL</searchLink>; Genomics Research Center, Academia Sinica, Taipei 115201, Taiwan.; Biomedical Translation Research Center, Academia Sinica, Taipei 115201, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lai+CY%22">Lai CY</searchLink>; Genomics Research Center, Academia Sinica, Taipei 115201, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chang+FL%22">Chang FL</searchLink>; Department of Ophthalmology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien 970473, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wu+SY%22">Wu SY</searchLink>; Department of Ophthalmology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien 970473, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+PY%22">Lin PY</searchLink>; Genomics Research Center, Academia Sinica, Taipei 115201, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chuang+CH%22">Chuang CH</searchLink>; Genomics Research Center, Academia Sinica, Taipei 115201, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chou+YX%22">Chou YX</searchLink>; Genomics Research Center, Academia Sinica, Taipei 115201, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+ZF%22">Chen ZF</searchLink>; Genomics Research Center, Academia Sinica, Taipei 115201, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wu+YC%22">Wu YC</searchLink>; Genomics Research Center, Academia Sinica, Taipei 115201, Taiwan.<br /><searchLink fieldCode="AU" term="%22Cheng+CL%22">Cheng CL</searchLink>; Genomics Research Center, Academia Sinica, Taipei 115201, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+H%22">Lin H</searchLink>; Genomics Research Center, Academia Sinica, Taipei 115201, Taiwan.; Research Center for Applied Sciences, Academia Sinica, Taipei 115201, Taiwan.<br /><searchLink fieldCode="AU" term="%22Ng+CH%22">Ng CH</searchLink>; Genomics Research Center, Academia Sinica, Taipei 115201, Taiwan.; Institute of Molecular and Cellular Biology, National Taiwan University, Taipei 106319, Taiwan.<br /><searchLink fieldCode="AU" term="%22Yang+SC%22">Yang SC</searchLink>; Genomics Research Center, Academia Sinica, Taipei 115201, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lu+J%22">Lu J</searchLink>; Doctoral Degree Program in Translational Medicine, Tzu Chi University and Academia Sinica, Hualien 970374, Taiwan.; Genomics Research Center, Academia Sinica, Taipei 115201, Taiwan.; Biomedical Translation Research Center, Academia Sinica, Taipei 115201, Taiwan.<br /><searchLink fieldCode="AU" term="%22Tsai+RK%22">Tsai RK</searchLink>; Doctoral Degree Program in Translational Medicine, Tzu Chi University and Academia Sinica, Hualien 970374, Taiwan.; Institute of Eye Research, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien 970473, Taiwan.; Institute of Medical Sciences, Tzu Chi University, Hualien 970374, Taiwan.
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  Data: <searchLink fieldCode="JN" term="%22101570734%22">Journal of functional biomaterials</searchLink> [J Funct Biomater] 2026 May 08; Vol. 17 (5). <i>Date of Electronic Publication: </i>2026 May 08.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22MDPI+AG%22">MDPI AG </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101570734 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2079-4983 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220794983%22">20794983 </searchLink><i>NLM ISO Abbreviation: </i>J Funct Biomater <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.3390/jfb17050236
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      – Code: eng
        Text: English
    Titles:
      – TitleFull: Direct Chemical Reprogramming of Human Fibroblasts into Retinal Progenitor-like Cells for Ocular Delivery.
        Type: main
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            – D: 08
              M: 05
              Text: 2026 May 08
              Type: published
              Y: 2026
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