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Early intervention with secukinumab prevents epigenetic scar development in new-onset psoriasis: STEPIn mechanistic substudy results.

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Title: Early intervention with secukinumab prevents epigenetic scar development in new-onset psoriasis: STEPIn mechanistic substudy results.
Authors: Gudjonsson JE; University of Michigan, Ann Arbor, Mich. Electronic address: johanng@med.umich.edu., Bier K; Novartis Biomedical Research, Basel, Switzerland., Gaulis S; Novartis Biomedical Research, Basel, Switzerland., Tsoi LC; University of Michigan, Ann Arbor, Mich., Cardner M; Novartis Biomedical Research, Basel, Switzerland; Novartis Pharma AG, Basel, Switzerland., Sarkar MK; University of Michigan, Ann Arbor, Mich., Coon A; University of Michigan, Ann Arbor, Mich., Cole C; University of Michigan, Ann Arbor, Mich., Kärner J; Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden., Fernandez A; Novartis Biomedical Research, Basel, Switzerland., Peters T; Novartis Biomedical Research, Basel, Switzerland., Eidsmo L; Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Gastro/Hud/Reuma, Karolinska University Hospital, Stockholm, Sweden., Iversen L; Aarhus University, Aarhus, Denmark., Jagiello P; Novartis Pharma AG, Basel, Switzerland., Ferrero E; Novartis Biomedical Research, Basel, Switzerland., Kolbinger F; Novartis Biomedical Research, Basel, Switzerland., Lohmann F; Novartis Biomedical Research, Basel, Switzerland. Electronic address: felix.lohmann@novartis.com., Conrad C; Department of Dermatology, Lausanne University Hospital CHUV and University of Lausanne, Lausanne, Switzerland. Electronic address: curdin.conrad@chuv.ch.
Source: The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2026 May 25. Date of Electronic Publication: 2026 May 25.
Publication Type: Journal Article
Journal Info: Publisher: Mosby Country of Publication: United States NLM ID: 1275002 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6825 (Electronic) Linking ISSN: 00916749 NLM ISO Abbreviation: J Allergy Clin Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Early intervention with secukinumab prevents epigenetic scar development in new-onset psoriasis: STEPIn mechanistic substudy results.
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  Data: <searchLink fieldCode="AU" term="%22Gudjonsson+JE%22">Gudjonsson JE</searchLink>; University of Michigan, Ann Arbor, Mich. Electronic address: johanng@med.umich.edu.<br /><searchLink fieldCode="AU" term="%22Bier+K%22">Bier K</searchLink>; Novartis Biomedical Research, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Gaulis+S%22">Gaulis S</searchLink>; Novartis Biomedical Research, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Tsoi+LC%22">Tsoi LC</searchLink>; University of Michigan, Ann Arbor, Mich.<br /><searchLink fieldCode="AU" term="%22Cardner+M%22">Cardner M</searchLink>; Novartis Biomedical Research, Basel, Switzerland; Novartis Pharma AG, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Sarkar+MK%22">Sarkar MK</searchLink>; University of Michigan, Ann Arbor, Mich.<br /><searchLink fieldCode="AU" term="%22Coon+A%22">Coon A</searchLink>; University of Michigan, Ann Arbor, Mich.<br /><searchLink fieldCode="AU" term="%22Cole+C%22">Cole C</searchLink>; University of Michigan, Ann Arbor, Mich.<br /><searchLink fieldCode="AU" term="%22Kärner+J%22">Kärner J</searchLink>; Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Fernandez+A%22">Fernandez A</searchLink>; Novartis Biomedical Research, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Peters+T%22">Peters T</searchLink>; Novartis Biomedical Research, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Eidsmo+L%22">Eidsmo L</searchLink>; Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Gastro/Hud/Reuma, Karolinska University Hospital, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Iversen+L%22">Iversen L</searchLink>; Aarhus University, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Jagiello+P%22">Jagiello P</searchLink>; Novartis Pharma AG, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Ferrero+E%22">Ferrero E</searchLink>; Novartis Biomedical Research, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Kolbinger+F%22">Kolbinger F</searchLink>; Novartis Biomedical Research, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Lohmann+F%22">Lohmann F</searchLink>; Novartis Biomedical Research, Basel, Switzerland. Electronic address: felix.lohmann@novartis.com.<br /><searchLink fieldCode="AU" term="%22Conrad+C%22">Conrad C</searchLink>; Department of Dermatology, Lausanne University Hospital CHUV and University of Lausanne, Lausanne, Switzerland. Electronic address: curdin.conrad@chuv.ch.
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  Data: <searchLink fieldCode="JN" term="%221275002%22">The Journal of allergy and clinical immunology</searchLink> [J Allergy Clin Immunol] 2026 May 25. <i>Date of Electronic Publication: </i>2026 May 25.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Mosby%22">Mosby </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>1275002 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1097-6825 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200916749%22">00916749 </searchLink><i>NLM ISO Abbreviation: </i>J Allergy Clin Immunol <i>Subsets: </i>MEDLINE
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