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Risk Factors in Sporadic Early-Onset Colorectal Cancer, Current Evidence and Emerging Insights: A Systematic Review.

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Title: Risk Factors in Sporadic Early-Onset Colorectal Cancer, Current Evidence and Emerging Insights: A Systematic Review.
Authors: Maddula M; Faculty of Medicine and Health, University of New South Wales, Sydney, NSW 2052, Australia., Cohen JE; Faculty of Medicine and Health, University of New South Wales, Sydney, NSW 2052, Australia., Kumarasinghe D; Department of Anaesthesia, Westmead Hospital, Sydney, NSW 2145, Australia., Ballinger ML; Centre for Molecular Oncology, University of New South Wales, Sydney, NSW 2052, Australia., Tearle JLE; School of Biomedical Sciences, University of New South Wales, Sydney, NSW 2052, Australia.; Garvan Institute of Medical Research, Darlinghurst, Sydney, NSW 2010, Australia., James KR; School of Biomedical Sciences, University of New South Wales, Sydney, NSW 2052, Australia.; Garvan Institute of Medical Research, Darlinghurst, Sydney, NSW 2010, Australia., Nagrial A; Department of Medical Oncology, Westmead Hospital, Sydney, NSW 2145, Australia., Barnet M; Faculty of Medicine and Health, University of New South Wales, Sydney, NSW 2052, Australia.; Garvan Institute of Medical Research, Darlinghurst, Sydney, NSW 2010, Australia.; The Kinghorn Centre, St Vincent's Health Network Sydney, Sydney, NSW 2010, Australia., Thavaneswaran S; Faculty of Medicine and Health, University of New South Wales, Sydney, NSW 2052, Australia.; Garvan Institute of Medical Research, Darlinghurst, Sydney, NSW 2010, Australia.; The Kinghorn Centre, St Vincent's Health Network Sydney, Sydney, NSW 2010, Australia.; NHMRC Clinical Trials Centre, The University of Sydney, Sydney, NSW 2050, Australia.
Source: Cancers [Cancers (Basel)] 2026 May 08; Vol. 18 (10). Date of Electronic Publication: 2026 May 08.
Publication Type: Journal Article; Review
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101526829 Publication Model: Electronic Cited Medium: Print ISSN: 2072-6694 (Print) Linking ISSN: 20726694 NLM ISO Abbreviation: Cancers (Basel) Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Risk Factors in Sporadic Early-Onset Colorectal Cancer, Current Evidence and Emerging Insights: A Systematic Review.
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  Data: <searchLink fieldCode="AU" term="%22Maddula+M%22">Maddula M</searchLink>; Faculty of Medicine and Health, University of New South Wales, Sydney, NSW 2052, Australia.<br /><searchLink fieldCode="AU" term="%22Cohen+JE%22">Cohen JE</searchLink>; Faculty of Medicine and Health, University of New South Wales, Sydney, NSW 2052, Australia.<br /><searchLink fieldCode="AU" term="%22Kumarasinghe+D%22">Kumarasinghe D</searchLink>; Department of Anaesthesia, Westmead Hospital, Sydney, NSW 2145, Australia.<br /><searchLink fieldCode="AU" term="%22Ballinger+ML%22">Ballinger ML</searchLink>; Centre for Molecular Oncology, University of New South Wales, Sydney, NSW 2052, Australia.<br /><searchLink fieldCode="AU" term="%22Tearle+JLE%22">Tearle JLE</searchLink>; School of Biomedical Sciences, University of New South Wales, Sydney, NSW 2052, Australia.; Garvan Institute of Medical Research, Darlinghurst, Sydney, NSW 2010, Australia.<br /><searchLink fieldCode="AU" term="%22James+KR%22">James KR</searchLink>; School of Biomedical Sciences, University of New South Wales, Sydney, NSW 2052, Australia.; Garvan Institute of Medical Research, Darlinghurst, Sydney, NSW 2010, Australia.<br /><searchLink fieldCode="AU" term="%22Nagrial+A%22">Nagrial A</searchLink>; Department of Medical Oncology, Westmead Hospital, Sydney, NSW 2145, Australia.<br /><searchLink fieldCode="AU" term="%22Barnet+M%22">Barnet M</searchLink>; Faculty of Medicine and Health, University of New South Wales, Sydney, NSW 2052, Australia.; Garvan Institute of Medical Research, Darlinghurst, Sydney, NSW 2010, Australia.; The Kinghorn Centre, St Vincent's Health Network Sydney, Sydney, NSW 2010, Australia.<br /><searchLink fieldCode="AU" term="%22Thavaneswaran+S%22">Thavaneswaran S</searchLink>; Faculty of Medicine and Health, University of New South Wales, Sydney, NSW 2052, Australia.; Garvan Institute of Medical Research, Darlinghurst, Sydney, NSW 2010, Australia.; The Kinghorn Centre, St Vincent's Health Network Sydney, Sydney, NSW 2010, Australia.; NHMRC Clinical Trials Centre, The University of Sydney, Sydney, NSW 2050, Australia.
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  Data: <searchLink fieldCode="JN" term="%22101526829%22">Cancers</searchLink> [Cancers (Basel)] 2026 May 08; Vol. 18 (10). <i>Date of Electronic Publication: </i>2026 May 08.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22MDPI%22">MDPI </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101526829 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2072-6694 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220726694%22">20726694 </searchLink><i>NLM ISO Abbreviation: </i>Cancers (Basel) <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.3390/cancers18101515
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      – Code: eng
        Text: English
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      – TitleFull: Risk Factors in Sporadic Early-Onset Colorectal Cancer, Current Evidence and Emerging Insights: A Systematic Review.
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            – D: 08
              M: 05
              Text: 2026 May 08
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              Y: 2026
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