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Antimicrobial Efficacy of Endogenous Blue Light Photoinactivation (400-470 nm) Against Escherichia coli: A Systematic Review of In Vitro Evidence and Clinical Implications.

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Title: Antimicrobial Efficacy of Endogenous Blue Light Photoinactivation (400-470 nm) Against Escherichia coli: A Systematic Review of In Vitro Evidence and Clinical Implications.
Authors: Mello DACPG; Health Sciences Graduate Program (PPGCS), Faculty of Medical Sciences of Santa Casa de São Paulo, São Paulo 01225-010, SP, Brazil., Afonso JPR; Human Movement and Rehabilitation Graduate Program (PPGMHR), Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil., Carvalho EE; Human Movement and Rehabilitation Graduate Program (PPGMHR), Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil., Appelt Filho HA; Health Sciences Graduate Program (PPGCS), Faculty of Medical Sciences of Santa Casa de São Paulo, São Paulo 01225-010, SP, Brazil.; Human Movement and Rehabilitation Graduate Program (PPGMHR), Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil., Ribeiro Júnior JBS; Health Sciences Graduate Program (PPGCS), Faculty of Medical Sciences of Santa Casa de São Paulo, São Paulo 01225-010, SP, Brazil.; Human Movement and Rehabilitation Graduate Program (PPGMHR), Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil., Alves LR; Health Sciences Graduate Program (PPGCS), Faculty of Medical Sciences of Santa Casa de São Paulo, São Paulo 01225-010, SP, Brazil.; Human Movement and Rehabilitation Graduate Program (PPGMHR), Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil., Sousa MBG; Human Movement and Rehabilitation Graduate Program (PPGMHR), Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil., Oliveira SA; Health Sciences Graduate Program (PPGCS), Faculty of Medical Sciences of Santa Casa de São Paulo, São Paulo 01225-010, SP, Brazil.; Human Movement and Rehabilitation Graduate Program (PPGMHR), Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil., Silva GQ; Health Sciences Graduate Program (PPGCS), Faculty of Medical Sciences of Santa Casa de São Paulo, São Paulo 01225-010, SP, Brazil.; Human Movement and Rehabilitation Graduate Program (PPGMHR), Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil., Bueno RS; Health Sciences Graduate Program (PPGCS), Faculty of Medical Sciences of Santa Casa de São Paulo, São Paulo 01225-010, SP, Brazil.; Human Movement and Rehabilitation Graduate Program (PPGMHR), Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil., Fernandes TV; Health Sciences Graduate Program (PPGCS), Faculty of Medical Sciences of Santa Casa de São Paulo, São Paulo 01225-010, SP, Brazil.; Hospital de Câncer de Barretos-Hospital do Amor, Barretos 14784-400, SP, Brazil., Marconi DG; Hospital de Câncer de Barretos-Hospital do Amor, Barretos 14784-400, SP, Brazil., Andraus RAC; Human Movement and Rehabilitation Graduate Program (PPGMHR), Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil., Silva CHM; Health Sciences Graduate Program (PPGCS), Faculty of Medical Sciences of Santa Casa de São Paulo, São Paulo 01225-010, SP, Brazil.; Human Movement and Rehabilitation Graduate Program (PPGMHR), Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil., Oliveira DAAP; Human Movement and Rehabilitation Graduate Program (PPGMHR), Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil., Oliveira-Silva I; Human Movement and Rehabilitation Graduate Program (PPGMHR), Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil., Oliveira RF; Human Movement and Rehabilitation Graduate Program (PPGMHR), Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil., Guedes OA; Dentistry Graduate Program (PPGO), Evangelical University of Goiás (UniEVANGELICA), Anápolis 01225-010, GO, Brazil., Freitas Júnior WR; Health Sciences Graduate Program (PPGCS), Faculty of Medical Sciences of Santa Casa de São Paulo, São Paulo 01225-010, SP, Brazil., Uriarte JJ; ARIES Research Group, Escuela Politécnica Superior, Universidad Nebrija, 28015 Madrid, Spain., Oliveira LVF; Human Movement and Rehabilitation Graduate Program (PPGMHR), Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil., Toledo LGM; Health Sciences Graduate Program (PPGCS), Faculty of Medical Sciences of Santa Casa de São Paulo, São Paulo 01225-010, SP, Brazil.
Source: Medical sciences (Basel, Switzerland) [Med Sci (Basel)] 2026 May 20; Vol. 14 (2). Date of Electronic Publication: 2026 May 20.
Publication Type: Journal Article; Systematic Review; Review; Research Support, Non-U.S. Gov't
Journal Info: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101629322 Publication Model: Electronic Cited Medium: Internet ISSN: 2076-3271 (Electronic) Linking ISSN: 20763271 NLM ISO Abbreviation: Med Sci (Basel) Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Antimicrobial Efficacy of Endogenous Blue Light Photoinactivation (400-470 nm) Against Escherichia coli: A Systematic Review of In Vitro Evidence and Clinical Implications.
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  Data: <searchLink fieldCode="AU" term="%22Mello+DACPG%22">Mello DACPG</searchLink>; Health Sciences Graduate Program (PPGCS), Faculty of Medical Sciences of Santa Casa de São Paulo, São Paulo 01225-010, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Afonso+JPR%22">Afonso JPR</searchLink>; Human Movement and Rehabilitation Graduate Program (PPGMHR), Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil.<br /><searchLink fieldCode="AU" term="%22Carvalho+EE%22">Carvalho EE</searchLink>; Human Movement and Rehabilitation Graduate Program (PPGMHR), Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil.<br /><searchLink fieldCode="AU" term="%22Appelt+Filho+HA%22">Appelt Filho HA</searchLink>; Health Sciences Graduate Program (PPGCS), Faculty of Medical Sciences of Santa Casa de São Paulo, São Paulo 01225-010, SP, Brazil.; Human Movement and Rehabilitation Graduate Program (PPGMHR), Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil.<br /><searchLink fieldCode="AU" term="%22Ribeiro+Júnior+JBS%22">Ribeiro Júnior JBS</searchLink>; Health Sciences Graduate Program (PPGCS), Faculty of Medical Sciences of Santa Casa de São Paulo, São Paulo 01225-010, SP, Brazil.; Human Movement and Rehabilitation Graduate Program (PPGMHR), Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil.<br /><searchLink fieldCode="AU" term="%22Alves+LR%22">Alves LR</searchLink>; Health Sciences Graduate Program (PPGCS), Faculty of Medical Sciences of Santa Casa de São Paulo, São Paulo 01225-010, SP, Brazil.; Human Movement and Rehabilitation Graduate Program (PPGMHR), Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil.<br /><searchLink fieldCode="AU" term="%22Sousa+MBG%22">Sousa MBG</searchLink>; Human Movement and Rehabilitation Graduate Program (PPGMHR), Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil.<br /><searchLink fieldCode="AU" term="%22Oliveira+SA%22">Oliveira SA</searchLink>; Health Sciences Graduate Program (PPGCS), Faculty of Medical Sciences of Santa Casa de São Paulo, São Paulo 01225-010, SP, Brazil.; Human Movement and Rehabilitation Graduate Program (PPGMHR), Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil.<br /><searchLink fieldCode="AU" term="%22Silva+GQ%22">Silva GQ</searchLink>; Health Sciences Graduate Program (PPGCS), Faculty of Medical Sciences of Santa Casa de São Paulo, São Paulo 01225-010, SP, Brazil.; Human Movement and Rehabilitation Graduate Program (PPGMHR), Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil.<br /><searchLink fieldCode="AU" term="%22Bueno+RS%22">Bueno RS</searchLink>; Health Sciences Graduate Program (PPGCS), Faculty of Medical Sciences of Santa Casa de São Paulo, São Paulo 01225-010, SP, Brazil.; Human Movement and Rehabilitation Graduate Program (PPGMHR), Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil.<br /><searchLink fieldCode="AU" term="%22Fernandes+TV%22">Fernandes TV</searchLink>; Health Sciences Graduate Program (PPGCS), Faculty of Medical Sciences of Santa Casa de São Paulo, São Paulo 01225-010, SP, Brazil.; Hospital de Câncer de Barretos-Hospital do Amor, Barretos 14784-400, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Marconi+DG%22">Marconi DG</searchLink>; Hospital de Câncer de Barretos-Hospital do Amor, Barretos 14784-400, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Andraus+RAC%22">Andraus RAC</searchLink>; Human Movement and Rehabilitation Graduate Program (PPGMHR), Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil.<br /><searchLink fieldCode="AU" term="%22Silva+CHM%22">Silva CHM</searchLink>; Health Sciences Graduate Program (PPGCS), Faculty of Medical Sciences of Santa Casa de São Paulo, São Paulo 01225-010, SP, Brazil.; Human Movement and Rehabilitation Graduate Program (PPGMHR), Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil.<br /><searchLink fieldCode="AU" term="%22Oliveira+DAAP%22">Oliveira DAAP</searchLink>; Human Movement and Rehabilitation Graduate Program (PPGMHR), Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil.<br /><searchLink fieldCode="AU" term="%22Oliveira-Silva+I%22">Oliveira-Silva I</searchLink>; Human Movement and Rehabilitation Graduate Program (PPGMHR), Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil.<br /><searchLink fieldCode="AU" term="%22Oliveira+RF%22">Oliveira RF</searchLink>; Human Movement and Rehabilitation Graduate Program (PPGMHR), Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil.<br /><searchLink fieldCode="AU" term="%22Guedes+OA%22">Guedes OA</searchLink>; Dentistry Graduate Program (PPGO), Evangelical University of Goiás (UniEVANGELICA), Anápolis 01225-010, GO, Brazil.<br /><searchLink fieldCode="AU" term="%22Freitas+Júnior+WR%22">Freitas Júnior WR</searchLink>; Health Sciences Graduate Program (PPGCS), Faculty of Medical Sciences of Santa Casa de São Paulo, São Paulo 01225-010, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Uriarte+JJ%22">Uriarte JJ</searchLink>; ARIES Research Group, Escuela Politécnica Superior, Universidad Nebrija, 28015 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Oliveira+LVF%22">Oliveira LVF</searchLink>; Human Movement and Rehabilitation Graduate Program (PPGMHR), Evangelical University of Goiás (UniEVANGELICA), Anápolis 75083-515, GO, Brazil.<br /><searchLink fieldCode="AU" term="%22Toledo+LGM%22">Toledo LGM</searchLink>; Health Sciences Graduate Program (PPGCS), Faculty of Medical Sciences of Santa Casa de São Paulo, São Paulo 01225-010, SP, Brazil.
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