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Evidence for overlapping genetic architecture between lifestyle factors and severe mental disorders with different patterns across diagnoses.

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Title: Evidence for overlapping genetic architecture between lifestyle factors and severe mental disorders with different patterns across diagnoses.
Authors: Rødevand L; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway. Electronic address: l.n.rodevand@medisin.uio.no., Rahman Z; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Jaholkowski P; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Parker N; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Valdimarsdóttir UA; Institute of Environmental Medicine, Unit of Integrative Epidemiology, Karolinska Institute, Stockholm, Sweden; Center of Public Health Sciences, Faculty of Medicine, University of Iceland, Reykjavík, Iceland., Smeland OB; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Tesfaye M; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway; Institute for Genomics in Health & Department of Psychiatry and Behavioral Sciences, SUNY Downstate Health Sciences University, Brooklyn, NY, USA., Parekh P; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway; Center for Multimodal Imaging and Genetics, J. Craig Venter Institute, La Jolla, CA, USA., Frei O; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway; Department of Pharmacy, Section for Pharmacology and Pharmaceutical Biosciences, University of Oslo, Oslo, Norway., Djurovic S; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway; Department of Medical Genetics, Oslo University Hospital and University of Oslo, Oslo, Norway., Steen NE; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway; Section for Clinical Psychosis Research, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway; Division of Mental Health and Substance abuse, Diakonhjemmet Hospital, Oslo, Norway., Dale AM; Center for Multimodal Imaging and Genetics, J. Craig Venter Institute, La Jolla, CA, USA; Oslo University Hospital, Oslo, Norway; University of California San Diego, La Jolla, CA, USA., Shadrin A; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Andreassen OA; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway. Electronic address: ole.andreassen@medisin.uio.no.
Source: EBioMedicine [EBioMedicine] 2026 Jun; Vol. 128, pp. 106304. Date of Electronic Publication: 2026 May 27.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101647039 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-3964 (Electronic) Linking ISSN: 23523964 NLM ISO Abbreviation: EBioMedicine Subsets: MEDLINE
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  Data: Evidence for overlapping genetic architecture between lifestyle factors and severe mental disorders with different patterns across diagnoses.
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  Data: <searchLink fieldCode="AU" term="%22Rødevand+L%22">Rødevand L</searchLink>; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway. Electronic address: l.n.rodevand@medisin.uio.no.<br /><searchLink fieldCode="AU" term="%22Rahman+Z%22">Rahman Z</searchLink>; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Jaholkowski+P%22">Jaholkowski P</searchLink>; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Parker+N%22">Parker N</searchLink>; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Valdimarsdóttir+UA%22">Valdimarsdóttir UA</searchLink>; Institute of Environmental Medicine, Unit of Integrative Epidemiology, Karolinska Institute, Stockholm, Sweden; Center of Public Health Sciences, Faculty of Medicine, University of Iceland, Reykjavík, Iceland.<br /><searchLink fieldCode="AU" term="%22Smeland+OB%22">Smeland OB</searchLink>; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Tesfaye+M%22">Tesfaye M</searchLink>; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway; Institute for Genomics in Health & Department of Psychiatry and Behavioral Sciences, SUNY Downstate Health Sciences University, Brooklyn, NY, USA.<br /><searchLink fieldCode="AU" term="%22Parekh+P%22">Parekh P</searchLink>; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway; Center for Multimodal Imaging and Genetics, J. Craig Venter Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Frei+O%22">Frei O</searchLink>; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway; Department of Pharmacy, Section for Pharmacology and Pharmaceutical Biosciences, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Djurovic+S%22">Djurovic S</searchLink>; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway; Department of Medical Genetics, Oslo University Hospital and University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Steen+NE%22">Steen NE</searchLink>; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway; Section for Clinical Psychosis Research, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway; Division of Mental Health and Substance abuse, Diakonhjemmet Hospital, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Dale+AM%22">Dale AM</searchLink>; Center for Multimodal Imaging and Genetics, J. Craig Venter Institute, La Jolla, CA, USA; Oslo University Hospital, Oslo, Norway; University of California San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Shadrin+A%22">Shadrin A</searchLink>; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Andreassen+OA%22">Andreassen OA</searchLink>; Centre for Precision Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway. Electronic address: ole.andreassen@medisin.uio.no.
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