Sustained and indirect effects of PCV10 reduced-dose schedules on pneumococcal carriage in Viet Nam: a long-term follow-up of a cluster-randomised controlled trial.

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Title: Sustained and indirect effects of PCV10 reduced-dose schedules on pneumococcal carriage in Viet Nam: a long-term follow-up of a cluster-randomised controlled trial.
Authors: Quilty BJ; Center for Global Health, Charité-Universitätmedizin Berlin, Berlin, Germany; Department of Infectious Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, UK; Centre for Mathematical Modelling of Infectious Diseases, London School of Hygiene & Tropical Medicine, London, UK. Electronic address: billy.quilty@charite.de., Toizumi M; Department of Pediatric Infectious Diseases, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan; Department of Global Health, School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan., Nguyen HAT; Department of Bacteriology, National Institute of Hygiene and Epidemiology, Hanoi, Viet Nam., Le LT; Department of Bacteriology, Pasteur Institute, Nha Trang, Viet Nam., Le HH; Department of Bacteriology, National Institute of Hygiene and Epidemiology, Hanoi, Viet Nam., Iwasaki C; Department of Pediatric Infectious Diseases, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan., Takegata M; Department of Pediatric Infectious Diseases, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan., Kitamura N; Department of Infectious Disease Dynamics, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan; Center for Infectious Disease Epidemiology, National Institute of Infectious Diseases, Japan Institute for Health Security, Tokyo, Japan., Shah MM; Department of Pediatric Infectious Diseases, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan., Nation ML; Infection, Immunity and Global Health, Murdoch Children's Research Institute, Melbourne, VIC, Australia; Department of Respiratory and Sleep Medicine, Royal Children's Hospital, Melbourne, VIC, Australia., Hinds J; Institute for Infection and Immunity, City St George's University of London, London, UK; BUGS Bioscience, London Bioscience Innovation Centre, London, UK., Zandvoort KV; Department of Infectious Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, UK; Centre for Mathematical Modelling of Infectious Diseases, London School of Hygiene & Tropical Medicine, London, UK., Ortika BD; Infection, Immunity and Global Health, Murdoch Children's Research Institute, Melbourne, VIC, Australia., Dunne EM; Infection, Immunity and Global Health, Murdoch Children's Research Institute, Melbourne, VIC, Australia., Satzke C; Infection, Immunity and Global Health, Murdoch Children's Research Institute, Melbourne, VIC, Australia; Department of Paediatrics, University of Melbourne, Melbourne, VIC, Australia; Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC, Australia., Do HT; Department of Pediatric Infectious Diseases, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan; Department of Bacteriology, Pasteur Institute, Nha Trang, Viet Nam., Mulholland K; Department of Infectious Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, UK; Infection, Immunity and Global Health, Murdoch Children's Research Institute, Melbourne, VIC, Australia; Department of Paediatrics, University of Melbourne, Melbourne, VIC, Australia., Dang DA; Department of Bacteriology, National Institute of Hygiene and Epidemiology, Hanoi, Viet Nam., Flasche S; Center for Global Health, Charité-Universitätmedizin Berlin, Berlin, Germany; Department of Infectious Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, UK; Centre for Mathematical Modelling of Infectious Diseases, London School of Hygiene & Tropical Medicine, London, UK; Department of Pediatric Infectious Diseases, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan., Yoshida LM; Department of Pediatric Infectious Diseases, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan; Department of Global Health, School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan; Nagasaki University Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan.
Source: The Lancet. Infectious diseases [Lancet Infect Dis] 2026 May 27. Date of Electronic Publication: 2026 May 27.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 101130150 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-4457 (Electronic) Linking ISSN: 14733099 NLM ISO Abbreviation: Lancet Infect Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Sustained and indirect effects of PCV10 reduced-dose schedules on pneumococcal carriage in Viet Nam: a long-term follow-up of a cluster-randomised controlled trial.
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  Data: <searchLink fieldCode="AU" term="%22Quilty+BJ%22">Quilty BJ</searchLink>; Center for Global Health, Charité-Universitätmedizin Berlin, Berlin, Germany; Department of Infectious Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, UK; Centre for Mathematical Modelling of Infectious Diseases, London School of Hygiene & Tropical Medicine, London, UK. Electronic address: billy.quilty@charite.de.<br /><searchLink fieldCode="AU" term="%22Toizumi+M%22">Toizumi M</searchLink>; Department of Pediatric Infectious Diseases, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan; Department of Global Health, School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Nguyen+HAT%22">Nguyen HAT</searchLink>; Department of Bacteriology, National Institute of Hygiene and Epidemiology, Hanoi, Viet Nam.<br /><searchLink fieldCode="AU" term="%22Le+LT%22">Le LT</searchLink>; Department of Bacteriology, Pasteur Institute, Nha Trang, Viet Nam.<br /><searchLink fieldCode="AU" term="%22Le+HH%22">Le HH</searchLink>; Department of Bacteriology, National Institute of Hygiene and Epidemiology, Hanoi, Viet Nam.<br /><searchLink fieldCode="AU" term="%22Iwasaki+C%22">Iwasaki C</searchLink>; Department of Pediatric Infectious Diseases, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Takegata+M%22">Takegata M</searchLink>; Department of Pediatric Infectious Diseases, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Kitamura+N%22">Kitamura N</searchLink>; Department of Infectious Disease Dynamics, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan; Center for Infectious Disease Epidemiology, National Institute of Infectious Diseases, Japan Institute for Health Security, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Shah+MM%22">Shah MM</searchLink>; Department of Pediatric Infectious Diseases, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Nation+ML%22">Nation ML</searchLink>; Infection, Immunity and Global Health, Murdoch Children's Research Institute, Melbourne, VIC, Australia; Department of Respiratory and Sleep Medicine, Royal Children's Hospital, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Hinds+J%22">Hinds J</searchLink>; Institute for Infection and Immunity, City St George's University of London, London, UK; BUGS Bioscience, London Bioscience Innovation Centre, London, UK.<br /><searchLink fieldCode="AU" term="%22Zandvoort+KV%22">Zandvoort KV</searchLink>; Department of Infectious Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, UK; Centre for Mathematical Modelling of Infectious Diseases, London School of Hygiene & Tropical Medicine, London, UK.<br /><searchLink fieldCode="AU" term="%22Ortika+BD%22">Ortika BD</searchLink>; Infection, Immunity and Global Health, Murdoch Children's Research Institute, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Dunne+EM%22">Dunne EM</searchLink>; Infection, Immunity and Global Health, Murdoch Children's Research Institute, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Satzke+C%22">Satzke C</searchLink>; Infection, Immunity and Global Health, Murdoch Children's Research Institute, Melbourne, VIC, Australia; Department of Paediatrics, University of Melbourne, Melbourne, VIC, Australia; Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Do+HT%22">Do HT</searchLink>; Department of Pediatric Infectious Diseases, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan; Department of Bacteriology, Pasteur Institute, Nha Trang, Viet Nam.<br /><searchLink fieldCode="AU" term="%22Mulholland+K%22">Mulholland K</searchLink>; Department of Infectious Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, UK; Infection, Immunity and Global Health, Murdoch Children's Research Institute, Melbourne, VIC, Australia; Department of Paediatrics, University of Melbourne, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Dang+DA%22">Dang DA</searchLink>; Department of Bacteriology, National Institute of Hygiene and Epidemiology, Hanoi, Viet Nam.<br /><searchLink fieldCode="AU" term="%22Flasche+S%22">Flasche S</searchLink>; Center for Global Health, Charité-Universitätmedizin Berlin, Berlin, Germany; Department of Infectious Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, UK; Centre for Mathematical Modelling of Infectious Diseases, London School of Hygiene & Tropical Medicine, London, UK; Department of Pediatric Infectious Diseases, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan.<br /><searchLink fieldCode="AU" term="%22Yoshida+LM%22">Yoshida LM</searchLink>; Department of Pediatric Infectious Diseases, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan; Department of Global Health, School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan; Nagasaki University Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan.
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  Data: <searchLink fieldCode="JN" term="%22101130150%22">The Lancet. Infectious diseases</searchLink> [Lancet Infect Dis] 2026 May 27. <i>Date of Electronic Publication: </i>2026 May 27.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science%22">Elsevier Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101130150 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1474-4457 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214733099%22">14733099 </searchLink><i>NLM ISO Abbreviation: </i>Lancet Infect Dis <i>Subsets: </i>MEDLINE
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        Value: 10.1016/S1473-3099(26)00172-6
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