View in EDS

Guidance on JAK inhibitor treatment for inborn errors of JAK-STAT signaling (2026). An international consensus statement on behalf of the ESID/EBMT-IEWP and ERN-RITA.

Saved in:
Bibliographic Details
Title: Guidance on JAK inhibitor treatment for inborn errors of JAK-STAT signaling (2026). An international consensus statement on behalf of the ESID/EBMT-IEWP and ERN-RITA.
Authors: Olbrich P; Instituto de Biomedicina de Sevilla, Research Group: 'Inborn Errors of Immunity', Pediatric Infectious Diseases, Rheumatology and Immunology Unit, IBiS/Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Red de Investigación Traslacional en Infectología Pediátrica RITIP, Av. Manuel Siurot, s/n. 41013, Seville, Spain; Departamento de Farmacología, Pediatría y Radiología, Facultad de Medicina, Universidad de Sevilla, Seville, Spain. Electronic address: carsten.speckmann@uniklinik-freiburg.de., Fischer M; Department of Allergology and Clinical Immunology, Children´s Hospital of Eastern Switzerland, Sankt Gallen, Switzerland; Center for Human Immunology, University of Zurich. Department of Quantitative Biomedicine, University of Zurich, Switzerland., Deyà-Martinez A; Institut de Recerca Hospital Sant Joan de Déu, Universitat de Barcelona, Esplugues, Spain; Clinical Immunology Unit Hospital, Sant Joan de Déu-Hospital Clínic de Barcelona, Barcelona, Spain., Campos-Asensio C; Biblioteca Médica, Hospital Universitario de Getafe, Getafe, Madrid, Spain., Neth O; Instituto de Biomedicina de Sevilla, Research Group: 'Inborn Errors of Immunity', Pediatric Infectious Diseases, Rheumatology and Immunology Unit, IBiS/Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Red de Investigación Traslacional en Infectología Pediátrica RITIP, Av. Manuel Siurot, s/n. 41013, Seville, Spain; Departamento de Farmacología, Pediatría y Radiología, Facultad de Medicina, Universidad de Sevilla, Seville, Spain., Hadjadj J; Sorbonne University, Department of Internal Medicine, APHP, Saint-Antoine Hospital, F-75012 Paris, France; Laboratory of Immunogenetics of Pediatric Autoimmune Diseases INSERM UMR 1163, Imagine Institute, University Paris Cité Paris France., Forbes Satter LR; Department of Pediatrics, Baylor College of Medicine, Houston, Tex; Texas Children's Hospital, Houston, Tex; USA; Department of Pediatrics, Baylor College of Medicine, Immunology/Allergy/Retrovirology, Texas Children's Hospital, Houston, Tex. USA., Leiding JW; Department of Pediatrics, Division of Allergy and Immunology, Johns Hopkins University, Baltimore, MD, USA; Institute for Clinical and Translational Research and Cancer and Blood Disorders Institute, Johns Hopkins All Children's Hospital, St. Petersburg, Florida, USA., Torgerson TR; Allen Institute for Immunology, Seattle, WA 98109, USA., Bakhtiar S; Division for Stem Cell Transplantation and Immunology, Department for Pediatrics, Goethe University Hospital Frankfurt, Frankfurt am Main, Germany., Baris S; Marmara University, Faculty of Medicine, Department of Pediatric Allergy and Immunology, Istanbul, Turkey; Istanbul Jeffrey Modell Diagnostic and Research Center for Primary Immunodeficiencies, Istanbul, Turkey; The Isil Berat Barlan Center for Translational Medicine, Istanbul, Turkey., Badolato R; Clinica pediatrica dell'Università degli Studi di Brescia; ASST Spedali civili, Brescia, Italy., Bloomfield M; Department of Immunology, Motol and Homolka University Hospital, 2nd Faculty of Medicine, Charles University, Prague, Czech Republic; Paediatric Department, Thomayer's University Hospital, 1st Faculty of Medicine, Charles University, Prague, Czech Republic., Buddingh EP; Willem-Alexander Children's Hospital, Leiden University Medical Center, Leiden, The Netherlands., Burroughs LM; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, Washington, USA; Department of Pediatrics, University of Washington School of Medicine, Seattle, Washington, USA., Burns S; Institute of Immunity and Transplantation, University College London, London, United Kingdom., Cooper MA; Department of Pediatrics, Division of Rheumatology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA., Crickx E; Service de médecine interne, Centre national de référence des cytopénies auto-immunes de l'adulte, Hôpital Henri Mondor, Fédération Hospitalo-Universitaire TRUE InnovaTive theRapy for immUne disorders, Assistance Publique Hôpitaux de Paris (AP-HP), Université Paris Est Créteil, France., Ehl S; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, University Medical Center, Faculty of Medicine, University of Freiburg, Germany., Farmand S; Division of Pediatric Stem Cell Transplantation and Immunology, Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Freeman AF; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA., Gonzalez-Granado LI; Hospital Universitario 12 de octubre, Madrid, Spain; Research Institute Hospital 12 octubre imas12, Madrid, Spain; Departamento de Pediatria. Universidad Complutente. Madrid. Spain., Hagin D; Allergy and Clinical Immunology Unit, Department of Medicine, Tel Aviv Sourasky Medical Center and Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Hanitsch LG; Institute of Medical Immunology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Germany; Humboldt Universität zu Berlin and Berlin Institute of Health, Berlin Institute of Health (BIH) Center for Regenerative Therapies, Berlin, Germany., Hanzlikova J; Department of Immunology and Allergology, Faculty of Medicine and Faculty Hospital, Pilsen, Czech Republic., Hauck F; Division of Pediatric Hematology/Oncology, Immunology and Rheumatology, Department of Pediatrics, Dr. von Hauner Children's Hospital, University Hospital, Ludwig-Maximilians-Universität München, Munich, Germany., Ivorra-Cortés J; Hospital Universitario y Politécnico la Fe, Valencia, Spain., Körholz J; Department of Pediatrics and University Center for Rare Diseases, Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Lankester AC; Willem-Alexander Children's Hospital, Department of Pediatrics, Pediatric Stem cell Transplantation program, Leiden University Medical Center, Leiden, The Netherlands., Leahy TR; Children's Health Ireland, Crumlin, Dublin, Ireland., Meyts I; Department of Microbiology, Immunology and Transplantation, Laboratory for Inborn Errors of Immunity, Katholieke Universiteit (KU) Leuven, Leuven, Belgium; Department of Pediatrics, University Hospitals Leuven, KU Leuven, Leuven, Belgium., Milner JD; Division of Allergy, Immunology and Rheumatology; Columbia University Medical Center; New York-Presbyterian Morgan Stanley Children's Hospital, USA., Nademi Z; Paediatric Department, Thomayer's University Hospital, 1st Faculty of Medicine, Charles University, Prague, Czech Republic; Paediatric Department, Thomayer's University Hospital, 1st Faculty of Medicine, Charles University, Prague, Czech Republic., Pachlopnik Schmid J; Division of Immunology, University Children's Hospital and Children's Research Center Zurich, Switzerland; Faculty of Medicine, University of Zurich, Switzerland., Pergent M; International Patient Organisation for Primary Immunodeficiencies (IPOPI), Brussels, Belgium., Prévot J; Department of Pediatrics, University of Washington School of Medicine, Seattle, Washington, USA; Department of Pediatrics, University of Washington School of Medicine, Seattle, Washington, USA., Rivière JG; Infection and Immunity in Pediatric Patients Research Group, Vall d'Hebron Institut de Recerca (VHIR), Barcelona, Catalonia Spain; Pediatric Infectious Diseases and Immunodeficiencies Unit, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Catalonia, Spain; Jeffrey Modell Diagnostic and Research Center for Primary Immunodeficiencies, Barcelona, Catalonia, Spain., Roxo-Junior P; Division of Immunology & Allergy, Dept.of Pediatrics, Ribeirão Preto Medical School, University of São Paulo, Brazil., Schuetz C; Department of Pediatrics and University Center for Rare Diseases, Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany; Department of Pediatrics and University Center for Rare Diseases, Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden, Dresden; Germany., Slatter MA; Children's Hematopoietic Stem Cell Transplant Unit, Great North Children's Hospital, Newcastle upon Tyne, United Kingdom; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom., Soler Palacín P; Infection and Immunity in Pediatric Patients Research Group, Vall d'Hebron Institut de Recerca (VHIR), Barcelona, Catalonia Spain; Pediatric Infectious Diseases and Immunodeficiencies Unit, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Catalonia, Spain; Jeffrey Modell Diagnostic and Research Center for Primary Immunodeficiencies, Barcelona, Catalonia, Spain., Warnatz K; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, University Medical Center, Faculty of Medicine, University of Freiburg, Germany; Department of Immunology, University Hospital Zurich, Zurich, Switzerland., Vítovcová P; Department of Allergology and Immunology, University Hospital Pilsen, Pilsen, Czech Republic., Vastert SJ; Department of Paediatric Rheumatology and Immunology, Wilhelmina Children's Hospital, University Medical Center Utrecht and Utrecht University, Utrecht, The Netherlands; Center for Translational Immunology, University Medical Center Utrecht, Utrecht, The Netherlands., Neven B; Immuno-hematology and Rheumatology Unit, Necker Children's Hospital, Assistance Publique-Hôpitaux de Paris, Université de Paris, Inserm 1163, Institut Imagine, Paris, Île-de-France, France., Albert MH; Institute for Clinical and Translational Research and Cancer and Blood Disorders Institute, Johns Hopkins All Children's Hospital, St. Petersburg, Florida, USA; Institute for Clinical and Translational Research and Cancer and Blood Disorders Institute, Johns Hopkins All Children's Hospital, St. Petersburg, Florida, USA., Speckmann C; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, University Medical Center, Faculty of Medicine, University of Freiburg, Germany; Division of Pediatric Hematology and Oncology, Childrens Hospital, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Corporate Authors: Inborn Errors Working Party of ESID/EBMT and the European Reference Network RITA
Source: The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2026 May 26. Date of Electronic Publication: 2026 May 26.
Publication Type: Journal Article
Journal Info: Publisher: Mosby Country of Publication: United States NLM ID: 1275002 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6825 (Electronic) Linking ISSN: 00916749 NLM ISO Abbreviation: J Allergy Clin Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 42203177
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Guidance on JAK inhibitor treatment for inborn errors of JAK-STAT signaling (2026). An international consensus statement on behalf of the ESID/EBMT-IEWP and ERN-RITA.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Olbrich+P%22">Olbrich P</searchLink>; Instituto de Biomedicina de Sevilla, Research Group: 'Inborn Errors of Immunity', Pediatric Infectious Diseases, Rheumatology and Immunology Unit, IBiS/Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Red de Investigación Traslacional en Infectología Pediátrica RITIP, Av. Manuel Siurot, s/n. 41013, Seville, Spain; Departamento de Farmacología, Pediatría y Radiología, Facultad de Medicina, Universidad de Sevilla, Seville, Spain. Electronic address: carsten.speckmann@uniklinik-freiburg.de.<br /><searchLink fieldCode="AU" term="%22Fischer+M%22">Fischer M</searchLink>; Department of Allergology and Clinical Immunology, Children´s Hospital of Eastern Switzerland, Sankt Gallen, Switzerland; Center for Human Immunology, University of Zurich. Department of Quantitative Biomedicine, University of Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Deyà-Martinez+A%22">Deyà-Martinez A</searchLink>; Institut de Recerca Hospital Sant Joan de Déu, Universitat de Barcelona, Esplugues, Spain; Clinical Immunology Unit Hospital, Sant Joan de Déu-Hospital Clínic de Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Campos-Asensio+C%22">Campos-Asensio C</searchLink>; Biblioteca Médica, Hospital Universitario de Getafe, Getafe, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Neth+O%22">Neth O</searchLink>; Instituto de Biomedicina de Sevilla, Research Group: 'Inborn Errors of Immunity', Pediatric Infectious Diseases, Rheumatology and Immunology Unit, IBiS/Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Red de Investigación Traslacional en Infectología Pediátrica RITIP, Av. Manuel Siurot, s/n. 41013, Seville, Spain; Departamento de Farmacología, Pediatría y Radiología, Facultad de Medicina, Universidad de Sevilla, Seville, Spain.<br /><searchLink fieldCode="AU" term="%22Hadjadj+J%22">Hadjadj J</searchLink>; Sorbonne University, Department of Internal Medicine, APHP, Saint-Antoine Hospital, F-75012 Paris, France; Laboratory of Immunogenetics of Pediatric Autoimmune Diseases INSERM UMR 1163, Imagine Institute, University Paris Cité Paris France.<br /><searchLink fieldCode="AU" term="%22Forbes+Satter+LR%22">Forbes Satter LR</searchLink>; Department of Pediatrics, Baylor College of Medicine, Houston, Tex; Texas Children's Hospital, Houston, Tex; USA; Department of Pediatrics, Baylor College of Medicine, Immunology/Allergy/Retrovirology, Texas Children's Hospital, Houston, Tex. USA.<br /><searchLink fieldCode="AU" term="%22Leiding+JW%22">Leiding JW</searchLink>; Department of Pediatrics, Division of Allergy and Immunology, Johns Hopkins University, Baltimore, MD, USA; Institute for Clinical and Translational Research and Cancer and Blood Disorders Institute, Johns Hopkins All Children's Hospital, St. Petersburg, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Torgerson+TR%22">Torgerson TR</searchLink>; Allen Institute for Immunology, Seattle, WA 98109, USA.<br /><searchLink fieldCode="AU" term="%22Bakhtiar+S%22">Bakhtiar S</searchLink>; Division for Stem Cell Transplantation and Immunology, Department for Pediatrics, Goethe University Hospital Frankfurt, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Baris+S%22">Baris S</searchLink>; Marmara University, Faculty of Medicine, Department of Pediatric Allergy and Immunology, Istanbul, Turkey; Istanbul Jeffrey Modell Diagnostic and Research Center for Primary Immunodeficiencies, Istanbul, Turkey; The Isil Berat Barlan Center for Translational Medicine, Istanbul, Turkey.<br /><searchLink fieldCode="AU" term="%22Badolato+R%22">Badolato R</searchLink>; Clinica pediatrica dell'Università degli Studi di Brescia; ASST Spedali civili, Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Bloomfield+M%22">Bloomfield M</searchLink>; Department of Immunology, Motol and Homolka University Hospital, 2nd Faculty of Medicine, Charles University, Prague, Czech Republic; Paediatric Department, Thomayer's University Hospital, 1st Faculty of Medicine, Charles University, Prague, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Buddingh+EP%22">Buddingh EP</searchLink>; Willem-Alexander Children's Hospital, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Burroughs+LM%22">Burroughs LM</searchLink>; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, Washington, USA; Department of Pediatrics, University of Washington School of Medicine, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Burns+S%22">Burns S</searchLink>; Institute of Immunity and Transplantation, University College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Cooper+MA%22">Cooper MA</searchLink>; Department of Pediatrics, Division of Rheumatology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA.<br /><searchLink fieldCode="AU" term="%22Crickx+E%22">Crickx E</searchLink>; Service de médecine interne, Centre national de référence des cytopénies auto-immunes de l'adulte, Hôpital Henri Mondor, Fédération Hospitalo-Universitaire TRUE InnovaTive theRapy for immUne disorders, Assistance Publique Hôpitaux de Paris (AP-HP), Université Paris Est Créteil, France.<br /><searchLink fieldCode="AU" term="%22Ehl+S%22">Ehl S</searchLink>; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, University Medical Center, Faculty of Medicine, University of Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Farmand+S%22">Farmand S</searchLink>; Division of Pediatric Stem Cell Transplantation and Immunology, Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Freeman+AF%22">Freeman AF</searchLink>; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Gonzalez-Granado+LI%22">Gonzalez-Granado LI</searchLink>; Hospital Universitario 12 de octubre, Madrid, Spain; Research Institute Hospital 12 octubre imas12, Madrid, Spain; Departamento de Pediatria. Universidad Complutente. Madrid. Spain.<br /><searchLink fieldCode="AU" term="%22Hagin+D%22">Hagin D</searchLink>; Allergy and Clinical Immunology Unit, Department of Medicine, Tel Aviv Sourasky Medical Center and Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.<br /><searchLink fieldCode="AU" term="%22Hanitsch+LG%22">Hanitsch LG</searchLink>; Institute of Medical Immunology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Germany; Humboldt Universität zu Berlin and Berlin Institute of Health, Berlin Institute of Health (BIH) Center for Regenerative Therapies, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Hanzlikova+J%22">Hanzlikova J</searchLink>; Department of Immunology and Allergology, Faculty of Medicine and Faculty Hospital, Pilsen, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Hauck+F%22">Hauck F</searchLink>; Division of Pediatric Hematology/Oncology, Immunology and Rheumatology, Department of Pediatrics, Dr. von Hauner Children's Hospital, University Hospital, Ludwig-Maximilians-Universität München, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Ivorra-Cortés+J%22">Ivorra-Cortés J</searchLink>; Hospital Universitario y Politécnico la Fe, Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22Körholz+J%22">Körholz J</searchLink>; Department of Pediatrics and University Center for Rare Diseases, Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Lankester+AC%22">Lankester AC</searchLink>; Willem-Alexander Children's Hospital, Department of Pediatrics, Pediatric Stem cell Transplantation program, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Leahy+TR%22">Leahy TR</searchLink>; Children's Health Ireland, Crumlin, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Meyts+I%22">Meyts I</searchLink>; Department of Microbiology, Immunology and Transplantation, Laboratory for Inborn Errors of Immunity, Katholieke Universiteit (KU) Leuven, Leuven, Belgium; Department of Pediatrics, University Hospitals Leuven, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Milner+JD%22">Milner JD</searchLink>; Division of Allergy, Immunology and Rheumatology; Columbia University Medical Center; New York-Presbyterian Morgan Stanley Children's Hospital, USA.<br /><searchLink fieldCode="AU" term="%22Nademi+Z%22">Nademi Z</searchLink>; Paediatric Department, Thomayer's University Hospital, 1st Faculty of Medicine, Charles University, Prague, Czech Republic; Paediatric Department, Thomayer's University Hospital, 1st Faculty of Medicine, Charles University, Prague, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Pachlopnik+Schmid+J%22">Pachlopnik Schmid J</searchLink>; Division of Immunology, University Children's Hospital and Children's Research Center Zurich, Switzerland; Faculty of Medicine, University of Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Pergent+M%22">Pergent M</searchLink>; International Patient Organisation for Primary Immunodeficiencies (IPOPI), Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Prévot+J%22">Prévot J</searchLink>; Department of Pediatrics, University of Washington School of Medicine, Seattle, Washington, USA; Department of Pediatrics, University of Washington School of Medicine, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Rivière+JG%22">Rivière JG</searchLink>; Infection and Immunity in Pediatric Patients Research Group, Vall d'Hebron Institut de Recerca (VHIR), Barcelona, Catalonia Spain; Pediatric Infectious Diseases and Immunodeficiencies Unit, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Catalonia, Spain; Jeffrey Modell Diagnostic and Research Center for Primary Immunodeficiencies, Barcelona, Catalonia, Spain.<br /><searchLink fieldCode="AU" term="%22Roxo-Junior+P%22">Roxo-Junior P</searchLink>; Division of Immunology & Allergy, Dept.of Pediatrics, Ribeirão Preto Medical School, University of São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Schuetz+C%22">Schuetz C</searchLink>; Department of Pediatrics and University Center for Rare Diseases, Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany; Department of Pediatrics and University Center for Rare Diseases, Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden, Dresden; Germany.<br /><searchLink fieldCode="AU" term="%22Slatter+MA%22">Slatter MA</searchLink>; Children's Hematopoietic Stem Cell Transplant Unit, Great North Children's Hospital, Newcastle upon Tyne, United Kingdom; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Soler+Palacín+P%22">Soler Palacín P</searchLink>; Infection and Immunity in Pediatric Patients Research Group, Vall d'Hebron Institut de Recerca (VHIR), Barcelona, Catalonia Spain; Pediatric Infectious Diseases and Immunodeficiencies Unit, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Catalonia, Spain; Jeffrey Modell Diagnostic and Research Center for Primary Immunodeficiencies, Barcelona, Catalonia, Spain.<br /><searchLink fieldCode="AU" term="%22Warnatz+K%22">Warnatz K</searchLink>; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, University Medical Center, Faculty of Medicine, University of Freiburg, Germany; Department of Immunology, University Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Vítovcová+P%22">Vítovcová P</searchLink>; Department of Allergology and Immunology, University Hospital Pilsen, Pilsen, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Vastert+SJ%22">Vastert SJ</searchLink>; Department of Paediatric Rheumatology and Immunology, Wilhelmina Children's Hospital, University Medical Center Utrecht and Utrecht University, Utrecht, The Netherlands; Center for Translational Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Neven+B%22">Neven B</searchLink>; Immuno-hematology and Rheumatology Unit, Necker Children's Hospital, Assistance Publique-Hôpitaux de Paris, Université de Paris, Inserm 1163, Institut Imagine, Paris, Île-de-France, France.<br /><searchLink fieldCode="AU" term="%22Albert+MH%22">Albert MH</searchLink>; Institute for Clinical and Translational Research and Cancer and Blood Disorders Institute, Johns Hopkins All Children's Hospital, St. Petersburg, Florida, USA; Institute for Clinical and Translational Research and Cancer and Blood Disorders Institute, Johns Hopkins All Children's Hospital, St. Petersburg, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Speckmann+C%22">Speckmann C</searchLink>; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, University Medical Center, Faculty of Medicine, University of Freiburg, Germany; Division of Pediatric Hematology and Oncology, Childrens Hospital, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
– Name: AuthorCorporate
  Label: Corporate Authors
  Group: Au
  Data: <searchLink fieldCode="CA" term="%22Inborn+Errors+Working+Party+of+ESID%2FEBMT+and+the+European+Reference+Network+RITA%22">Inborn Errors Working Party of ESID/EBMT and the European Reference Network RITA</searchLink>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%221275002%22">The Journal of allergy and clinical immunology</searchLink> [J Allergy Clin Immunol] 2026 May 26. <i>Date of Electronic Publication: </i>2026 May 26.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Mosby%22">Mosby </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>1275002 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1097-6825 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200916749%22">00916749 </searchLink><i>NLM ISO Abbreviation: </i>J Allergy Clin Immunol <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42203177
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1016/j.jaci.2026.05.005
    Languages:
      – Code: eng
        Text: English
    Titles:
      – TitleFull: Guidance on JAK inhibitor treatment for inborn errors of JAK-STAT signaling (2026). An international consensus statement on behalf of the ESID/EBMT-IEWP and ERN-RITA.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Olbrich P
      – PersonEntity:
          Name:
            NameFull: Fischer M
      – PersonEntity:
          Name:
            NameFull: Deyà-Martinez A
      – PersonEntity:
          Name:
            NameFull: Campos-Asensio C
      – PersonEntity:
          Name:
            NameFull: Neth O
      – PersonEntity:
          Name:
            NameFull: Hadjadj J
      – PersonEntity:
          Name:
            NameFull: Forbes Satter LR
      – PersonEntity:
          Name:
            NameFull: Leiding JW
      – PersonEntity:
          Name:
            NameFull: Torgerson TR
      – PersonEntity:
          Name:
            NameFull: Bakhtiar S
      – PersonEntity:
          Name:
            NameFull: Baris S
      – PersonEntity:
          Name:
            NameFull: Badolato R
      – PersonEntity:
          Name:
            NameFull: Bloomfield M
      – PersonEntity:
          Name:
            NameFull: Buddingh EP
      – PersonEntity:
          Name:
            NameFull: Burroughs LM
      – PersonEntity:
          Name:
            NameFull: Burns S
      – PersonEntity:
          Name:
            NameFull: Cooper MA
      – PersonEntity:
          Name:
            NameFull: Crickx E
      – PersonEntity:
          Name:
            NameFull: Ehl S
      – PersonEntity:
          Name:
            NameFull: Farmand S
      – PersonEntity:
          Name:
            NameFull: Freeman AF
      – PersonEntity:
          Name:
            NameFull: Gonzalez-Granado LI
      – PersonEntity:
          Name:
            NameFull: Hagin D
      – PersonEntity:
          Name:
            NameFull: Hanitsch LG
      – PersonEntity:
          Name:
            NameFull: Hanzlikova J
      – PersonEntity:
          Name:
            NameFull: Hauck F
      – PersonEntity:
          Name:
            NameFull: Ivorra-Cortés J
      – PersonEntity:
          Name:
            NameFull: Körholz J
      – PersonEntity:
          Name:
            NameFull: Lankester AC
      – PersonEntity:
          Name:
            NameFull: Leahy TR
      – PersonEntity:
          Name:
            NameFull: Meyts I
      – PersonEntity:
          Name:
            NameFull: Milner JD
      – PersonEntity:
          Name:
            NameFull: Nademi Z
      – PersonEntity:
          Name:
            NameFull: Pachlopnik Schmid J
      – PersonEntity:
          Name:
            NameFull: Pergent M
      – PersonEntity:
          Name:
            NameFull: Prévot J
      – PersonEntity:
          Name:
            NameFull: Rivière JG
      – PersonEntity:
          Name:
            NameFull: Roxo-Junior P
      – PersonEntity:
          Name:
            NameFull: Schuetz C
      – PersonEntity:
          Name:
            NameFull: Slatter MA
      – PersonEntity:
          Name:
            NameFull: Soler Palacín P
      – PersonEntity:
          Name:
            NameFull: Warnatz K
      – PersonEntity:
          Name:
            NameFull: Vítovcová P
      – PersonEntity:
          Name:
            NameFull: Vastert SJ
      – PersonEntity:
          Name:
            NameFull: Neven B
      – PersonEntity:
          Name:
            NameFull: Albert MH
      – PersonEntity:
          Name:
            NameFull: Speckmann C
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 26
              M: 05
              Text: 2026 May 26
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1097-6825
          Titles:
            – TitleFull: The Journal of allergy and clinical immunology
              Type: main
ResultId 1