Excitatory paraventricular thalamus-posterior insular cortex circuit mediates pain-anxiety comorbidity in diabetic neuropathy.

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Title: Excitatory paraventricular thalamus-posterior insular cortex circuit mediates pain-anxiety comorbidity in diabetic neuropathy.
Authors: Wei M; Department of Anesthesiology, Peking University Third Hospital, Beijing, China., Shou J; Department of Anesthesiology, Peking University Third Hospital, Beijing, China., Yang J; Department of Anesthesiology, Peking University Third Hospital, Beijing, China., Cai S; Neuroscience Research Institute, Peking University, Beijing, China.; Department of Neurobiology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China.; Key Laboratory for Neuroscience, Ministry of Education of China and National Health Commission of China, Beijing, China., Bai Q; Neuroscience Research Institute, Peking University, Beijing, China.; Department of Neurobiology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China.; Key Laboratory for Neuroscience, Ministry of Education of China and National Health Commission of China, Beijing, China., Hou J; Neuroscience Research Institute, Peking University, Beijing, China.; Department of Neurobiology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China.; Key Laboratory for Neuroscience, Ministry of Education of China and National Health Commission of China, Beijing, China., Jiang Y; Department of Anesthesiology, Peking University Third Hospital, Beijing, China., Shen S; Department of Anesthesiology, Peking University Third Hospital, Beijing, China., Yu Z; Department of Anesthesiology, Peking University Third Hospital, Beijing, China., Zhao X; Department of Anesthesiology, Peking University Third Hospital, Beijing, China., Han Y; Department of Anesthesiology, Peking University Third Hospital, Beijing, China., Cai J; Neuroscience Research Institute, Peking University, Beijing, China.; Department of Neurobiology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China.; Key Laboratory for Neuroscience, Ministry of Education of China and National Health Commission of China, Beijing, China., Yang XW; Department of Endocrinology, Peking University First Hospital, Beijing, China., Li Z; Department of Anesthesiology, Peking University Third Hospital, Beijing, China., Ma D; Department of Anesthesiology, The First Affiliated Hospital, Ningbo University, Ningbo, China. d.ma@imperial.ac.uk.; Perioperative and Systems Medicine Laboratory, Department of Anesthesiology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Children and Adolescent's Health and Diseases, Hangzhou, China. d.ma@imperial.ac.uk.; Division of Anaesthetics, Pain Medicine and Intensive Care, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Chelsea & Westminster Hospital, London, UK. d.ma@imperial.ac.uk., Xing GG; Neuroscience Research Institute, Peking University, Beijing, China. ggxing@bjmu.edu.cn.; Department of Neurobiology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China. ggxing@bjmu.edu.cn.; Key Laboratory for Neuroscience, Ministry of Education of China and National Health Commission of China, Beijing, China. ggxing@bjmu.edu.cn., Li M; Department of Anesthesiology, Peking University Third Hospital, Beijing, China. liminanesth@bjmu.edu.cn.
Source: Translational psychiatry [Transl Psychiatry] 2026 May 27; Vol. 16 (1). Date of Electronic Publication: 2026 May 27.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101562664 Publication Model: Electronic Cited Medium: Internet ISSN: 2158-3188 (Electronic) Linking ISSN: 21583188 NLM ISO Abbreviation: Transl Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
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