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Polygenic scores for risk of pancreatic ductal adenocarcinoma: evaluation of novel and published models.

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Title: Polygenic scores for risk of pancreatic ductal adenocarcinoma: evaluation of novel and published models.
Authors: Antwi SO; Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, FL, USA. Antwi.Samuel@mayo.edu., Coombes BJ; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA., Carlson EE; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA., Larson NB; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA., Rabe KG; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA., Atkinson HJ; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA., Majumder S; Department of Medicine, Mayo Clinic, Rochester, MN, USA., Bamlet WR; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA., Schaid DJ; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA., Zhong J; Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., McKean D; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, MD, USA., Arslan AA; Department of Obstetrics and Gynecology, New York University Grossman School of Medicine, New York, NY, USA.; Department of Population Health, New York University Grossman School of Medicine, New York, NY, USA.; Perlmutter Cancer Center, NYU Langone Health, New York, NY, USA., Beane Freeman LE; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Bracci PM; Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, USA., Canzian F; Genomic Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany., Truong T; Paris-Saclay University, UVSQ, Inserm, Gustave Roussy, CESP, Villejuif, France., Atkins J; Nuffield Department of Population Health, Oxford University, Oxford, UK., Du M; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Gallinger S; Lunenfeld-Tanenbaum Research Institute, Sinai Health System and University of Toronto, Toronto, ON, Canada., Goodman PJ; SWOG Statistical Center, Fred Hutchinson Cancer Center, Seattle, WA, USA., Katzke V; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Campa D; Department of Biology, University of Pisa, Pisa, PI, Italy., Kooperberg C; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA., Le Marchand L; Cancer Epidemiology Program, University of Hawaii Cancer Center, Honolulu, HI, USA., Neale RE; Population Health Program, QIMR Berghofer, Brisbane, QLD, Australia.; School of Public Health, University of Queensland, Brisbane, QLD, Australia., Patel AV; Department of Population Science, American Cancer Society, Atlanta, GA, USA., Wactawski-Wende J; University at Buffalo School of Public Health and Health Professions, Buffalo, NY, USA., Perdomo S; Genomic Epidemiology Branch, International Agency for Research on Cancer, Lyon, France., Shu XO; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA., Visvanathan K; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, MD, USA.; Department of Epidemiology, Johns Hopkins School of Public Health, Baltimore, MD, USA., Van Den Eeden SK; Division of Research, Kaiser Permanente Northern California, Pleasanton, CA, USA., White E; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA., Zheng W; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA., Albanes D; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Andreotti G; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Brennan P; Genomic Epidemiology Branch, International Agency for Research on Cancer, Lyon, France., Chanock SJ; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Chen Y; Department of Population Health, New York University Grossman School of Medicine, New York, NY, USA.; Perlmutter Cancer Center, NYU Langone Health, New York, NY, USA.; New York University Grossman School of Medicine, New York, NY, USA., Darst B; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA., Ferrari P; Nutrition and Metabolism Branch, International Agency for Research on Cancer, World Health Organization, Lyon, France., Giovannucci EL; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Goggins M; Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins School of Medicine, Baltimore, MD, USA., Haiman C; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Hassan M; Department of Gastrointestinal Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Hung RJ; Lunenfeld-Tanenbaum Research Institute, Sinai Health System and University of Toronto, Toronto, ON, Canada., Jones MR; Department of Epidemiology, Johns Hopkins School of Public Health, Baltimore, MD, USA., Kraft P; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Malats N; Genetic and Molecular Epidemiology Group, Spanish National Cancer Research Centre, Madrid, Spain., Moore SC; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Ng K; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Peters U; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA., Porta M; CIBER Epidemiologíay Salud Pública (CIBERESP), Barcelona, Spain.; Hospital del Mar Institute of Medical Research (IMIM), Universitat Autònoma de Barcelona, Barcelona, Spain., Rothman N; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Sánchez MJ; Escuela Andaluza de Salud Pública (EASP), Granada, Spain.; Instituto de Investigación Biosanitaria ibs.GRANADA, Granada, Spain.; Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain., Sesso HD; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA., Silverman DT; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Southey MC; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia.; Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, VIC, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, Australia., Milne RL; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia.; Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, VIC, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, Australia., Um CY; Department of Population Science, American Cancer Society, Atlanta, GA, USA., Yu H; Cancer Epidemiology Program, University of Hawaii Cancer Center, Honolulu, HI, USA., Yuan C; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Risch HA; Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, CT, USA., Wolpin BM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Stolzenberg-Solomon RZ; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Klein AP; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, MD, USA.; Department of Epidemiology, Johns Hopkins School of Public Health, Baltimore, MD, USA.; Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins School of Medicine, Baltimore, MD, USA., Amundadottir LT; Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Oberg AL; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA. Ann.oberg@mayo.edu.
Corporate Authors: MAYO-RGC Project Generation, Regeneron Genetics Center
Source: NPJ precision oncology [NPJ Precis Oncol] 2026 May 27. Date of Electronic Publication: 2026 May 27.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature Country of Publication: England NLM ID: 101708166 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2397-768X (Print) Linking ISSN: 2397768X NLM ISO Abbreviation: NPJ Precis Oncol
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  Data: Polygenic scores for risk of pancreatic ductal adenocarcinoma: evaluation of novel and published models.
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          Dates:
            – D: 27
              M: 05
              Text: 2026 May 27
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-print
              Value: 2397-768X
          Titles:
            – TitleFull: NPJ precision oncology
              Type: main
ResultId 1