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Shotgun metagenomic mapping of saliva reveals insights into diversity and function of the oral microbiome in pregnancy.

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Title: Shotgun metagenomic mapping of saliva reveals insights into diversity and function of the oral microbiome in pregnancy.
Authors: Bostanci N; Division of Oral Health and Periodontology, Department of Dental Medicine, Karolinska Institutet, Stockholm, Sweden. nagihan.bostanci@ki.se., Antony AT; Department of Medical Biochemistry and Microbiology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Silbereisen A; Division of Oral Health and Periodontology, Department of Dental Medicine, Karolinska Institutet, Stockholm, Sweden., Esmaili T; Division of Oral Health and Periodontology, Department of Dental Medicine, Karolinska Institutet, Stockholm, Sweden., Krog MC; The Recurrent Pregnancy Loss Units, Copenhagen University Hospitals, Rigshospitalet and Hvidovre Hospital, Copenhagen, Denmark.; Department of Clinical Immunology, Copenhagen University Hospital, Rigshospitalet, Denmark., Sterpu I; Department of Clinical Science and Education, and Division of Obstetrics and Gynaecology, Department of Clinical Science, Intervention and Technology, Karolinska Institute, Södersjukhuset, Stockholm, Sweden., Bashir Z; The Recurrent Pregnancy Loss Units, Copenhagen University Hospitals, Rigshospitalet and Hvidovre Hospital, Copenhagen, Denmark.; Department of Obstetrics and Gynaecology, Holbæk Hospital, Holbæk, Denmark., Engstrand L; Department of Microbiology, Tumor and Cell Biology, Centre for Translational Microbiome Research, Karolinska Institutet, Stockholm, Sweden., Wiberg-Itzel E; Department of Clinical Science and Education, and Division of Obstetrics and Gynaecology, Department of Clinical Science, Intervention and Technology, Karolinska Institute, Södersjukhuset, Stockholm, Sweden., Nielsen HS; The Recurrent Pregnancy Loss Units, Copenhagen University Hospitals, Rigshospitalet and Hvidovre Hospital, Copenhagen, Denmark.; Department of Obstetrics and Gynaecology, Hvidovre Hospital, Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Hugerth LW; Department of Medical Biochemistry and Microbiology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Schuppe-Koistinen I; Department of Microbiology, Tumor and Cell Biology, Centre for Translational Microbiome Research, Karolinska Institutet, Stockholm, Sweden.
Source: Scientific reports [Sci Rep] 2026 May 27; Vol. 16 (1). Date of Electronic Publication: 2026 May 27.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Bostanci+N%22">Bostanci N</searchLink>; Division of Oral Health and Periodontology, Department of Dental Medicine, Karolinska Institutet, Stockholm, Sweden. nagihan.bostanci@ki.se.<br /><searchLink fieldCode="AU" term="%22Antony+AT%22">Antony AT</searchLink>; Department of Medical Biochemistry and Microbiology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Silbereisen+A%22">Silbereisen A</searchLink>; Division of Oral Health and Periodontology, Department of Dental Medicine, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Esmaili+T%22">Esmaili T</searchLink>; Division of Oral Health and Periodontology, Department of Dental Medicine, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Krog+MC%22">Krog MC</searchLink>; The Recurrent Pregnancy Loss Units, Copenhagen University Hospitals, Rigshospitalet and Hvidovre Hospital, Copenhagen, Denmark.; Department of Clinical Immunology, Copenhagen University Hospital, Rigshospitalet, Denmark.<br /><searchLink fieldCode="AU" term="%22Sterpu+I%22">Sterpu I</searchLink>; Department of Clinical Science and Education, and Division of Obstetrics and Gynaecology, Department of Clinical Science, Intervention and Technology, Karolinska Institute, Södersjukhuset, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Bashir+Z%22">Bashir Z</searchLink>; The Recurrent Pregnancy Loss Units, Copenhagen University Hospitals, Rigshospitalet and Hvidovre Hospital, Copenhagen, Denmark.; Department of Obstetrics and Gynaecology, Holbæk Hospital, Holbæk, Denmark.<br /><searchLink fieldCode="AU" term="%22Engstrand+L%22">Engstrand L</searchLink>; Department of Microbiology, Tumor and Cell Biology, Centre for Translational Microbiome Research, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Wiberg-Itzel+E%22">Wiberg-Itzel E</searchLink>; Department of Clinical Science and Education, and Division of Obstetrics and Gynaecology, Department of Clinical Science, Intervention and Technology, Karolinska Institute, Södersjukhuset, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Nielsen+HS%22">Nielsen HS</searchLink>; The Recurrent Pregnancy Loss Units, Copenhagen University Hospitals, Rigshospitalet and Hvidovre Hospital, Copenhagen, Denmark.; Department of Obstetrics and Gynaecology, Hvidovre Hospital, Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Hugerth+LW%22">Hugerth LW</searchLink>; Department of Medical Biochemistry and Microbiology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Schuppe-Koistinen+I%22">Schuppe-Koistinen I</searchLink>; Department of Microbiology, Tumor and Cell Biology, Centre for Translational Microbiome Research, Karolinska Institutet, Stockholm, Sweden.
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