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Combating small extracellular vesicle-mediated immunological barriers in the tumor microenvironment via strategically activatable PEGylated peptides.

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Title: Combating small extracellular vesicle-mediated immunological barriers in the tumor microenvironment via strategically activatable PEGylated peptides.
Authors: Kim CH; School of Chemical Engineering, College of Engineering, Sungkyunkwan University, Suwon, Republic of Korea., Ko H; Korea Preclinical Evaluation Center, Korea Research Institute of Bioscience & Biotechnology, Daejeon, Republic of Korea., Lee JA; School of Chemical Engineering, College of Engineering, Sungkyunkwan University, Suwon, Republic of Korea., Kim SH; School of Chemical Engineering, College of Engineering, Sungkyunkwan University, Suwon, Republic of Korea., Park M; Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Gangnam-gu, Seoul, Republic of Korea., Lee CH; School of Chemical Engineering, College of Engineering, Sungkyunkwan University, Suwon, Republic of Korea., Shin S; School of Chemical Engineering, College of Engineering, Sungkyunkwan University, Suwon, Republic of Korea., Shin JM; Department of Polymer Science and Engineering, Korea National University of Transportation, Chungju, Republic of Korea., Son S; School of Chemical Engineering, College of Engineering, Sungkyunkwan University, Suwon, Republic of Korea., Lee J; School of Chemical Engineering, College of Engineering, Sungkyunkwan University, Suwon, Republic of Korea., Kang H; School of Chemical Engineering, College of Engineering, Sungkyunkwan University, Suwon, Republic of Korea., Cho S; Department of MetaBioHealth, SKKU Institute for Convergence, Sungkyunkwan University, Suwon, Republic of Korea., Chang J; Department of MetaBioHealth, SKKU Institute for Convergence, Sungkyunkwan University, Suwon, Republic of Korea., Kim J; Department of MetaBioHealth, SKKU Institute for Convergence, Sungkyunkwan University, Suwon, Republic of Korea., Jang WH; School of Chemical Engineering, College of Engineering, Sungkyunkwan University, Suwon, Republic of Korea., Kim MJ; School of Chemical Engineering, College of Engineering, Sungkyunkwan University, Suwon, Republic of Korea., Jackman JA; School of Chemical Engineering, College of Engineering, Sungkyunkwan University, Suwon, Republic of Korea.; Biomedical Institute for Convergence at SKKU (BICS), Sungkyunkwan University, Suwon, Republic of Korea.; Translational Nanobioscience Research Center, Sungkyunkwan University, Suwon, Republic of Korea., Park JH; School of Chemical Engineering, College of Engineering, Sungkyunkwan University, Suwon, Republic of Korea. jhpark1@skku.edu.; Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Gangnam-gu, Seoul, Republic of Korea. jhpark1@skku.edu.; Department of MetaBioHealth, SKKU Institute for Convergence, Sungkyunkwan University, Suwon, Republic of Korea. jhpark1@skku.edu.; Biomedical Institute for Convergence at SKKU (BICS), Sungkyunkwan University, Suwon, Republic of Korea. jhpark1@skku.edu.; ExoStemTech Inc., 55 Hanyangdaehak-ro, Sangnok-gu, Ansan, Republic of Korea. jhpark1@skku.edu.
Source: Signal transduction and targeted therapy [Signal Transduct Target Ther] 2026 May 28; Vol. 11 (1). Date of Electronic Publication: 2026 May 28.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101676423 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-3635 (Electronic) Linking ISSN: 20593635 NLM ISO Abbreviation: Signal Transduct Target Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Kim+CH%22">Kim CH</searchLink>; School of Chemical Engineering, College of Engineering, Sungkyunkwan University, Suwon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Ko+H%22">Ko H</searchLink>; Korea Preclinical Evaluation Center, Korea Research Institute of Bioscience & Biotechnology, Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+JA%22">Lee JA</searchLink>; School of Chemical Engineering, College of Engineering, Sungkyunkwan University, Suwon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+SH%22">Kim SH</searchLink>; School of Chemical Engineering, College of Engineering, Sungkyunkwan University, Suwon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+M%22">Park M</searchLink>; Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Gangnam-gu, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+CH%22">Lee CH</searchLink>; School of Chemical Engineering, College of Engineering, Sungkyunkwan University, Suwon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Shin+S%22">Shin S</searchLink>; School of Chemical Engineering, College of Engineering, Sungkyunkwan University, Suwon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Shin+JM%22">Shin JM</searchLink>; Department of Polymer Science and Engineering, Korea National University of Transportation, Chungju, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Son+S%22">Son S</searchLink>; School of Chemical Engineering, College of Engineering, Sungkyunkwan University, Suwon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+J%22">Lee J</searchLink>; School of Chemical Engineering, College of Engineering, Sungkyunkwan University, Suwon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kang+H%22">Kang H</searchLink>; School of Chemical Engineering, College of Engineering, Sungkyunkwan University, Suwon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Cho+S%22">Cho S</searchLink>; Department of MetaBioHealth, SKKU Institute for Convergence, Sungkyunkwan University, Suwon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Chang+J%22">Chang J</searchLink>; Department of MetaBioHealth, SKKU Institute for Convergence, Sungkyunkwan University, Suwon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+J%22">Kim J</searchLink>; Department of MetaBioHealth, SKKU Institute for Convergence, Sungkyunkwan University, Suwon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jang+WH%22">Jang WH</searchLink>; School of Chemical Engineering, College of Engineering, Sungkyunkwan University, Suwon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+MJ%22">Kim MJ</searchLink>; School of Chemical Engineering, College of Engineering, Sungkyunkwan University, Suwon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jackman+JA%22">Jackman JA</searchLink>; School of Chemical Engineering, College of Engineering, Sungkyunkwan University, Suwon, Republic of Korea.; Biomedical Institute for Convergence at SKKU (BICS), Sungkyunkwan University, Suwon, Republic of Korea.; Translational Nanobioscience Research Center, Sungkyunkwan University, Suwon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+JH%22">Park JH</searchLink>; School of Chemical Engineering, College of Engineering, Sungkyunkwan University, Suwon, Republic of Korea. jhpark1@skku.edu.; Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Gangnam-gu, Seoul, Republic of Korea. jhpark1@skku.edu.; Department of MetaBioHealth, SKKU Institute for Convergence, Sungkyunkwan University, Suwon, Republic of Korea. jhpark1@skku.edu.; Biomedical Institute for Convergence at SKKU (BICS), Sungkyunkwan University, Suwon, Republic of Korea. jhpark1@skku.edu.; ExoStemTech Inc., 55 Hanyangdaehak-ro, Sangnok-gu, Ansan, Republic of Korea. jhpark1@skku.edu.
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