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Mitochondrial calcium uptake drives organelle remodeling to promote inflammasome-dependent cytokine release.

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Title: Mitochondrial calcium uptake drives organelle remodeling to promote inflammasome-dependent cytokine release.
Authors: Gherardi G; Department of Biomedical Sciences, University of Padua, Padua, Italy., Spinelli F; Department of Biomedical Sciences, University of Padua, Padua, Italy., Sbrissa M; Department of Biomedical Sciences, University of Padua, Padua, Italy., Quagliata M; Department of Biomedical Sciences, University of Padua, Padua, Italy., Luisetto R; Department of Surgery, Oncology and Gastroenterology, University of Padua, Padua, Italy., Scanu A; Rehabilitation Unit, Department of Neuroscience, University of Padua, Padua, Italy., Vezzoli E; ALEMBIC Advanced Light and Electron Microscopy Experimental Imaging Center, IRCCS San Raffaele Scientific Hospital, Milan, Italy., Carraro M; Department of Biomedical Sciences, University of Padua, Padua, Italy., Casey AM; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge, UK., Branco TF; Department of Biology, University of Padua, Padua, Italy., Ishihara N; Department of Biological Sciences, Graduate School of Science, Osaka University, Toyonaka, Japan., Mattarei A; Department of Pharmaceutical and Pharmacological Sciences, University of Padua, Padua, Italy., Masiero S; Rehabilitation Unit, Department of Neuroscience, University of Padua, Padua, Italy.; Department of Neuroscience, Physical Medicine and Rehabilitation School, University of Padua, Padua, Italy., Murphy MP; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge, UK.; Department of Medicine, University of Cambridge, Cambridge, UK., Bernardi P; Department of Biomedical Sciences, University of Padua, Padua, Italy., Tacchetti C; Experimental Imaging Center, IRCCS San Raffaele Hospital, Milan, Italy.; School of Medicine, Vita-Salute San Raffaele University, Milan, Italy., Scorrano L; Department of Biology, University of Padua, Padua, Italy.; Veneto Institute of Molecular Medicine, Padua, Italy., Raffaello A; Department of Biomedical Sciences, University of Padua, Padua, Italy., Rizzuto R; Department of Biomedical Sciences, University of Padua, Padua, Italy. rosario.rizzuto@unipd.it.; National Center for Gene Therapy and Drugs based on RNA Technology, Padua, Italy. rosario.rizzuto@unipd.it.
Source: Cell death and differentiation [Cell Death Differ] 2026 May 27. Date of Electronic Publication: 2026 May 27.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9437445 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5403 (Electronic) Linking ISSN: 13509047 NLM ISO Abbreviation: Cell Death Differ Subsets: MEDLINE
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