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Enhancing persistence while managing cytokine release syndrome to embrace next-generation CAR-T cell therapy.

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Title: Enhancing persistence while managing cytokine release syndrome to embrace next-generation CAR-T cell therapy.
Authors: Yang Y; Department of Rehabilitation, Tangdu Hospital, Air-Force Medical University (The Fourth Military Medical University), Xi'an, 86-710038, China.; Department of Immunology, the Key Laboratory of Bio-Hazard Damage and Prevention Medicine, Basic Medicine School, Air-Force Medical University (The Fourth Military Medical University), Xi'an, 86-710032, China., Sun Y; Department of Immunology, the Key Laboratory of Bio-Hazard Damage and Prevention Medicine, Basic Medicine School, Air-Force Medical University (The Fourth Military Medical University), Xi'an, 86-710032, China., Kang H; Department of Immunology, the Key Laboratory of Bio-Hazard Damage and Prevention Medicine, Basic Medicine School, Air-Force Medical University (The Fourth Military Medical University), Xi'an, 86-710032, China., Guan E; Department of Immunology, the Key Laboratory of Bio-Hazard Damage and Prevention Medicine, Basic Medicine School, Air-Force Medical University (The Fourth Military Medical University), Xi'an, 86-710032, China., Liu R; Department of Rehabilitation, Tangdu Hospital, Air-Force Medical University (The Fourth Military Medical University), Xi'an, 86-710038, China. tdliurui@fmmu.edu.cn., Yang K; Department of Immunology, the Key Laboratory of Bio-Hazard Damage and Prevention Medicine, Basic Medicine School, Air-Force Medical University (The Fourth Military Medical University), Xi'an, 86-710032, China. yangkunkun@fmmu.edu.cn., Jiang D; Department of Rehabilitation, Tangdu Hospital, Air-Force Medical University (The Fourth Military Medical University), Xi'an, 86-710038, China. superjames1991@foxmail.com.; Department of Immunology, the Key Laboratory of Bio-Hazard Damage and Prevention Medicine, Basic Medicine School, Air-Force Medical University (The Fourth Military Medical University), Xi'an, 86-710032, China. superjames1991@foxmail.com.
Source: Journal of translational medicine [J Transl Med] 2026 May 27; Vol. 24 (1). Date of Electronic Publication: 2026 May 27.
Publication Type: Journal Article; Review
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876 (Electronic) Linking ISSN: 14795876 NLM ISO Abbreviation: J Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1479-5876
DOI:10.1186/s12967-026-08299-4