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SIRPA ablation inhibits intimal hyperplasia by promoting PPARγ-regulated alternative macrophage polarization.

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Title: SIRPA ablation inhibits intimal hyperplasia by promoting PPARγ-regulated alternative macrophage polarization.
Authors: He T; Department of Cardiology, Zhongnan Hospital, Wuhan University, Wuhan 430071, China.; Institute of Myocardial Injury and Repair, Wuhan University, Wuhan 430071, China., Wu X; Department of Cardiology, Zhongnan Hospital, Wuhan University, Wuhan 430071, China.; Institute of Myocardial Injury and Repair, Wuhan University, Wuhan 430071, China., Zhang Q; Pediatric Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Tian R; Department of Cardiology, Zhongnan Hospital, Wuhan University, Wuhan 430071, China.; Institute of Myocardial Injury and Repair, Wuhan University, Wuhan 430071, China., Jin Z; Department of Cardiology, Zhongnan Hospital, Wuhan University, Wuhan 430071, China.; Institute of Myocardial Injury and Repair, Wuhan University, Wuhan 430071, China., Jiang FX; Department of Cardiology, Zhongnan Hospital, Wuhan University, Wuhan 430071, China.; Institute of Myocardial Injury and Repair, Wuhan University, Wuhan 430071, China., Kong X; Department of Cardiology, Zhongnan Hospital, Wuhan University, Wuhan 430071, China.; Institute of Myocardial Injury and Repair, Wuhan University, Wuhan 430071, China., Peng L; Department of Cardiology, Zhongnan Hospital, Wuhan University, Wuhan 430071, China.; Institute of Myocardial Injury and Repair, Wuhan University, Wuhan 430071, China., Chen M; Department of Cardiology, Zhongnan Hospital, Wuhan University, Wuhan 430071, China.; Institute of Myocardial Injury and Repair, Wuhan University, Wuhan 430071, China., Zhao F; Department of Cardiology, Zhongnan Hospital, Wuhan University, Wuhan 430071, China.; Institute of Myocardial Injury and Repair, Wuhan University, Wuhan 430071, China., Wang H; Department of Cardiology, Zhongnan Hospital, Wuhan University, Wuhan 430071, China.; Institute of Myocardial Injury and Repair, Wuhan University, Wuhan 430071, China., Cheng WL; Department of Cardiology, Zhongnan Hospital, Wuhan University, Wuhan 430071, China.; Institute of Myocardial Injury and Repair, Wuhan University, Wuhan 430071, China.
Source: Clinical science (London, England : 1979) [Clin Sci (Lond)] 2026 Jul 15; Vol. 140 (7), pp. 1285-1301.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Portland Press on behalf of the Medical Research Society and the Biochemical Society Country of Publication: England NLM ID: 7905731 Publication Model: Print Cited Medium: Internet ISSN: 1470-8736 (Electronic) Linking ISSN: 01435221 NLM ISO Abbreviation: Clin Sci (Lond) Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: SIRPA ablation inhibits intimal hyperplasia by promoting PPARγ-regulated alternative macrophage polarization.
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  Data: <searchLink fieldCode="AU" term="%22He+T%22">He T</searchLink>; Department of Cardiology, Zhongnan Hospital, Wuhan University, Wuhan 430071, China.; Institute of Myocardial Injury and Repair, Wuhan University, Wuhan 430071, China.<br /><searchLink fieldCode="AU" term="%22Wu+X%22">Wu X</searchLink>; Department of Cardiology, Zhongnan Hospital, Wuhan University, Wuhan 430071, China.; Institute of Myocardial Injury and Repair, Wuhan University, Wuhan 430071, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Q%22">Zhang Q</searchLink>; Pediatric Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Tian+R%22">Tian R</searchLink>; Department of Cardiology, Zhongnan Hospital, Wuhan University, Wuhan 430071, China.; Institute of Myocardial Injury and Repair, Wuhan University, Wuhan 430071, China.<br /><searchLink fieldCode="AU" term="%22Jin+Z%22">Jin Z</searchLink>; Department of Cardiology, Zhongnan Hospital, Wuhan University, Wuhan 430071, China.; Institute of Myocardial Injury and Repair, Wuhan University, Wuhan 430071, China.<br /><searchLink fieldCode="AU" term="%22Jiang+FX%22">Jiang FX</searchLink>; Department of Cardiology, Zhongnan Hospital, Wuhan University, Wuhan 430071, China.; Institute of Myocardial Injury and Repair, Wuhan University, Wuhan 430071, China.<br /><searchLink fieldCode="AU" term="%22Kong+X%22">Kong X</searchLink>; Department of Cardiology, Zhongnan Hospital, Wuhan University, Wuhan 430071, China.; Institute of Myocardial Injury and Repair, Wuhan University, Wuhan 430071, China.<br /><searchLink fieldCode="AU" term="%22Peng+L%22">Peng L</searchLink>; Department of Cardiology, Zhongnan Hospital, Wuhan University, Wuhan 430071, China.; Institute of Myocardial Injury and Repair, Wuhan University, Wuhan 430071, China.<br /><searchLink fieldCode="AU" term="%22Chen+M%22">Chen M</searchLink>; Department of Cardiology, Zhongnan Hospital, Wuhan University, Wuhan 430071, China.; Institute of Myocardial Injury and Repair, Wuhan University, Wuhan 430071, China.<br /><searchLink fieldCode="AU" term="%22Zhao+F%22">Zhao F</searchLink>; Department of Cardiology, Zhongnan Hospital, Wuhan University, Wuhan 430071, China.; Institute of Myocardial Injury and Repair, Wuhan University, Wuhan 430071, China.<br /><searchLink fieldCode="AU" term="%22Wang+H%22">Wang H</searchLink>; Department of Cardiology, Zhongnan Hospital, Wuhan University, Wuhan 430071, China.; Institute of Myocardial Injury and Repair, Wuhan University, Wuhan 430071, China.<br /><searchLink fieldCode="AU" term="%22Cheng+WL%22">Cheng WL</searchLink>; Department of Cardiology, Zhongnan Hospital, Wuhan University, Wuhan 430071, China.; Institute of Myocardial Injury and Repair, Wuhan University, Wuhan 430071, China.
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  Data: <searchLink fieldCode="JN" term="%227905731%22">Clinical science (London, England : 1979)</searchLink> [Clin Sci (Lond)] 2026 Jul 15; Vol. 140 (7), pp. 1285-1301.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Portland+Press+on+behalf+of+the+Medical+Research+Society+and+the+Biochemical+Society%22">Portland Press on behalf of the Medical Research Society and the Biochemical Society </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>7905731 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1470-8736 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201435221%22">01435221 </searchLink><i>NLM ISO Abbreviation: </i>Clin Sci (Lond) <i>Subsets: </i>MEDLINE
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        Value: 10.1042/CS20250499
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              Text: 2026 Jul 15
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