Exosomal CircGANAB promotes cancer progression and immunotherapy resistance by degrading interacting RNAs and limiting T cell infiltration in pancreatic ductal adenocarcinoma.
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| Title: | Exosomal CircGANAB promotes cancer progression and immunotherapy resistance by degrading interacting RNAs and limiting T cell infiltration in pancreatic ductal adenocarcinoma. |
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| Authors: | Wong CH; School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, NT, Hong Kong; Shenzhen Research Institute, The Chinese University of Hong Kong, Shenzhen 518087, China., Peña-Paladines JJ; School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, NT, Hong Kong., Luo Z; School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, NT, Hong Kong., Ma CY; School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, NT, Hong Kong., Lee YL; School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, NT, Hong Kong., Lin ZX; School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, NT, Hong Kong., Xian YF; School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, NT, Hong Kong., Hollingsworth MA; Fred and Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE, USA., To KF; Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong., Chen Y; School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, NT, Hong Kong; Shenzhen Research Institute, The Chinese University of Hong Kong, Shenzhen 518087, China. Electronic address: yangchaochen@cuhk.edu.hk. |
| Source: | Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy [Drug Resist Updat] 2026 Jul; Vol. 87, pp. 101416. Date of Electronic Publication: 2026 May 23. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Churchill Livingstone Country of Publication: Scotland NLM ID: 9815369 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-2084 (Electronic) Linking ISSN: 13687646 NLM ISO Abbreviation: Drug Resist Updat Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42208081 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Exosomal CircGANAB promotes cancer progression and immunotherapy resistance by degrading interacting RNAs and limiting T cell infiltration in pancreatic ductal adenocarcinoma. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Wong+CH%22">Wong CH</searchLink>; School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, NT, Hong Kong; Shenzhen Research Institute, The Chinese University of Hong Kong, Shenzhen 518087, China.<br /><searchLink fieldCode="AU" term="%22Peña-Paladines+JJ%22">Peña-Paladines JJ</searchLink>; School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, NT, Hong Kong.<br /><searchLink fieldCode="AU" term="%22Luo+Z%22">Luo Z</searchLink>; School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, NT, Hong Kong.<br /><searchLink fieldCode="AU" term="%22Ma+CY%22">Ma CY</searchLink>; School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, NT, Hong Kong.<br /><searchLink fieldCode="AU" term="%22Lee+YL%22">Lee YL</searchLink>; School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, NT, Hong Kong.<br /><searchLink fieldCode="AU" term="%22Lin+ZX%22">Lin ZX</searchLink>; School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, NT, Hong Kong.<br /><searchLink fieldCode="AU" term="%22Xian+YF%22">Xian YF</searchLink>; School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, NT, Hong Kong.<br /><searchLink fieldCode="AU" term="%22Hollingsworth+MA%22">Hollingsworth MA</searchLink>; Fred and Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE, USA.<br /><searchLink fieldCode="AU" term="%22To+KF%22">To KF</searchLink>; Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong.<br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, NT, Hong Kong; Shenzhen Research Institute, The Chinese University of Hong Kong, Shenzhen 518087, China. Electronic address: yangchaochen@cuhk.edu.hk. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229815369%22">Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy</searchLink> [Drug Resist Updat] 2026 Jul; Vol. 87, pp. 101416. <i>Date of Electronic Publication: </i>2026 May 23. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Churchill+Livingstone%22">Churchill Livingstone </searchLink><i>Country of Publication: </i>Scotland <i>NLM ID: </i>9815369 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1532-2084 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213687646%22">13687646 </searchLink><i>NLM ISO Abbreviation: </i>Drug Resist Updat <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42208081 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.drup.2026.101416 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 101416 Titles: – TitleFull: Exosomal CircGANAB promotes cancer progression and immunotherapy resistance by degrading interacting RNAs and limiting T cell infiltration in pancreatic ductal adenocarcinoma. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Wong CH – PersonEntity: Name: NameFull: Peña-Paladines JJ – PersonEntity: Name: NameFull: Luo Z – PersonEntity: Name: NameFull: Ma CY – PersonEntity: Name: NameFull: Lee YL – PersonEntity: Name: NameFull: Lin ZX – PersonEntity: Name: NameFull: Xian YF – PersonEntity: Name: NameFull: Hollingsworth MA – PersonEntity: Name: NameFull: To KF – PersonEntity: Name: NameFull: Chen Y IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 07 Text: 2026 Jul Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1532-2084 Numbering: – Type: volume Value: 87 Titles: – TitleFull: Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy Type: main |
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