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A causal link between autoantibodies and neurological symptoms in long COVID.

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Title: A causal link between autoantibodies and neurological symptoms in long COVID.
Authors: de Sá KSG; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA; Center for Infection and Immunity, Yale University School of Medicine, New Haven, CT 06519, USA., Silva J; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA; Center for Infection and Immunity, Yale University School of Medicine, New Haven, CT 06519, USA., Bayarri-Olmos R; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA; Center for Infection and Immunity, Yale University School of Medicine, New Haven, CT 06519, USA., Baker CA; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA; Center for Infection and Immunity, Yale University School of Medicine, New Haven, CT 06519, USA., Lu Z; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA; Center for Infection and Immunity, Yale University School of Medicine, New Haven, CT 06519, USA., Gipson W; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA; Center for Infection and Immunity, Yale University School of Medicine, New Haven, CT 06519, USA., Na D; Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT 06520, USA., Chen B; Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT 06520, USA., Wenxue L; Center for Infection and Immunity, Yale University School of Medicine, New Haven, CT 06519, USA; Yale Cancer Biology Institute, Yale University, West Haven, CT 06516, USA., Khosroabadi D; Center for Infection and Immunity, Yale University School of Medicine, New Haven, CT 06519, USA; Yale Cancer Biology Institute, Yale University, West Haven, CT 06516, USA., Brinda R; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA; Center for Infection and Immunity, Yale University School of Medicine, New Haven, CT 06519, USA., Constable RAR; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA; Center for Infection and Immunity, Yale University School of Medicine, New Haven, CT 06519, USA., Omene B; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA; Center for Infection and Immunity, Yale University School of Medicine, New Haven, CT 06519, USA., Colom Díaz PA; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA; Center for Infection and Immunity, Yale University School of Medicine, New Haven, CT 06519, USA., Kwon DI; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA; Center for Infection and Immunity, Yale University School of Medicine, New Haven, CT 06519, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA., Rodrigues G; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA; Center for Infection and Immunity, Yale University School of Medicine, New Haven, CT 06519, USA., Heidecke H; CellTrend GmbH, Luckenwalde 14943, Germany., Schulze-Forster K; CellTrend GmbH, Luckenwalde 14943, Germany., Gross A; SeromYx Systems, Woburn, MA 01801, USA., Shneer T; SeromYx Systems, Woburn, MA 01801, USA., Clarke A; SeromYx Systems, Woburn, MA 01801, USA., Linnekin T; SeromYx Systems, Woburn, MA 01801, USA., Brate A; SeromYx Systems, Woburn, MA 01801, USA., Brown L; SeromYx Systems, Woburn, MA 01801, USA., Buda H; SeromYx Systems, Woburn, MA 01801, USA., Jatiani S; SeromYx Systems, Woburn, MA 01801, USA., Moise L; SeromYx Systems, Woburn, MA 01801, USA., Greene K; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA; Center for Infection and Immunity, Yale University School of Medicine, New Haven, CT 06519, USA., Bhagchandani S; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA; Center for Infection and Immunity, Yale University School of Medicine, New Haven, CT 06519, USA., Bhattacharjee B; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA; Center for Infection and Immunity, Yale University School of Medicine, New Haven, CT 06519, USA., Gehlhausen J; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA; Center for Infection and Immunity, Yale University School of Medicine, New Haven, CT 06519, USA., Wood J; Cohen Center for Recovery from Complex Chronic Illness, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Tabacof L; Cohen Center for Recovery from Complex Chronic Illness, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Scheibenbogen C; Institute of Medical Immunology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt Universität zu Berlin and Berlin Institute of Health (BIH), Berlin, Germany., Liu Y; Center for Infection and Immunity, Yale University School of Medicine, New Haven, CT 06519, USA; Yale Cancer Biology Institute, Yale University, West Haven, CT 06516, USA., Guan L; Center for Infection and Immunity, Yale University School of Medicine, New Haven, CT 06519, USA; Department of Biostatistics, Yale University School of Public Health, New Haven, CT 06510, USA., Schneeberger Pane M; Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT 06520, USA., Putrino D; Cohen Center for Recovery from Complex Chronic Illness, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address: david.putrino@mountsinai.org., Horvath TL; Center for Infection and Immunity, Yale University School of Medicine, New Haven, CT 06519, USA; Department of Comparative Medicine, Yale University School of Medicine, New Haven, CT 06520, USA. Electronic address: tamas.horvath@yale.edu., Iwasaki A; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA; Center for Infection and Immunity, Yale University School of Medicine, New Haven, CT 06519, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address: akiko.iwasaki@yale.edu.
Source: Cell [Cell] 2026 May 28; Vol. 189 (11), pp. 3214-3235.e37.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A causal link between autoantibodies and neurological symptoms in long COVID.
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  Data: <searchLink fieldCode="AU" term="%22de+Sá+KSG%22">de Sá KSG</searchLink>; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA; Center for Infection and Immunity, Yale University School of Medicine, New Haven, CT 06519, USA.<br /><searchLink fieldCode="AU" term="%22Silva+J%22">Silva J</searchLink>; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA; Center for Infection and Immunity, Yale University School of Medicine, New Haven, CT 06519, USA.<br /><searchLink fieldCode="AU" term="%22Bayarri-Olmos+R%22">Bayarri-Olmos R</searchLink>; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA; Center for Infection and Immunity, Yale University School of Medicine, New Haven, CT 06519, USA.<br /><searchLink fieldCode="AU" term="%22Baker+CA%22">Baker CA</searchLink>; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA; Center for Infection and Immunity, Yale University School of Medicine, New Haven, CT 06519, USA.<br /><searchLink fieldCode="AU" term="%22Lu+Z%22">Lu Z</searchLink>; 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Center for Infection and Immunity, Yale University School of Medicine, New Haven, CT 06519, USA; Department of Biostatistics, Yale University School of Public Health, New Haven, CT 06510, USA.<br /><searchLink fieldCode="AU" term="%22Schneeberger+Pane+M%22">Schneeberger Pane M</searchLink>; Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT 06520, USA.<br /><searchLink fieldCode="AU" term="%22Putrino+D%22">Putrino D</searchLink>; Cohen Center for Recovery from Complex Chronic Illness, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. 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