View in EDS

The endogenous peptide GPR15L shapes the intestinal microbiota to counteract colitis.

Saved in:
Bibliographic Details
Title: The endogenous peptide GPR15L shapes the intestinal microbiota to counteract colitis.
Authors: Leggio M; Department of Medicine 1, University Hospital Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Schramm S; Department of Medicine 1, University Hospital Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.; Deutsches Zentrum Immuntherapie, University Hospital Erlangen, Erlangen, Germany., Dietz L; Department of Medicine 1, University Hospital Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Ocón B; Laboratory of Immunology and Vascular Biology, Department of Pathology, Stanford University School of Medicine and Palo Alto Veterans Medical Center, Stanford, Palo Alto, California, USA., Wirtz S; Department of Medicine 1, University Hospital Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.; Deutsches Zentrum Immuntherapie, University Hospital Erlangen, Erlangen, Germany., Puertolas Balint F; Department of Molecular Biology, Umeå University, Umeå, Sweden.; Laboratory for Molecular Infection Medicine Sweden (MIMS) and Umeå Center for Microbial Research (UCMR), Umeå University, Umeå, Sweden., Yilmaz B; Maurice Müller Laboratories, Department for Biomedical Research, University of Bern, Bern, Switzerland., Petzold J; Institute of Clinical Microbiology, Immunology and Hygiene, University Hospital Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Liu LJ; Department of Medicine 1, University Hospital Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Dedden M; Department of Medicine 1, University Hospital Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Ekici A; Institute of Human Genetics, University Hospital Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Meng X; Department of Medicine 1, University Hospital Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Bingham D; Department of Pathology, Stanford University School of Medicine, Stanford, California, USA., Ullrich KA; Department of Medicine 1, University Hospital Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Heltmann-Meyer S; Department of Medicine 1, University Hospital Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.; Deutsches Zentrum Immuntherapie, University Hospital Erlangen, Erlangen, Germany., Günther C; Department of Medicine 1, University Hospital Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.; Deutsches Zentrum Immuntherapie, University Hospital Erlangen, Erlangen, Germany., Hildner K; Department of Medicine 1, University Hospital Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.; Deutsches Zentrum Immuntherapie, University Hospital Erlangen, Erlangen, Germany., Atreya R; Department of Medicine 1, University Hospital Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.; Deutsches Zentrum Immuntherapie, University Hospital Erlangen, Erlangen, Germany., Atreya I; Department of Medicine 1, University Hospital Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Müller TM; Department of Medicine 1, University Hospital Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.; Deutsches Zentrum Immuntherapie, University Hospital Erlangen, Erlangen, Germany., Gerlach RG; Institute of Clinical Microbiology, Immunology and Hygiene, University Hospital Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Schroeder BO; Department of Molecular Biology, Umeå University, Umeå, Sweden.; Laboratory for Molecular Infection Medicine Sweden (MIMS) and Umeå Center for Microbial Research (UCMR), Umeå University, Umeå, Sweden., Macpherson A; Maurice Müller Laboratories, Department for Biomedical Research, University of Bern, Bern, Switzerland., Butcher EC; Laboratory of Immunology and Vascular Biology, Department of Pathology, Stanford University School of Medicine and Palo Alto Veterans Medical Center, Stanford, Palo Alto, California, USA., Neurath MF; Department of Medicine 1, University Hospital Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.; Deutsches Zentrum Immuntherapie, University Hospital Erlangen, Erlangen, Germany., Zundler S; Department of Medicine 1, University Hospital Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany sebastian.zundler@uk-erlangen.de.; Deutsches Zentrum Immuntherapie, University Hospital Erlangen, Erlangen, Germany.
Corporate Authors: TRR241 IBDome Consortium, TRR241 IBCome Consortium
Source: Gut [Gut] 2026 Jun 25. Date of Electronic Publication: 2026 Jun 25.
Publication Type: Journal Article
Journal Info: Publisher: British Medical Assn Country of Publication: England NLM ID: 2985108R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-3288 (Electronic) Linking ISSN: 00175749 NLM ISO Abbreviation: Gut Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 42209192
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: The endogenous peptide GPR15L shapes the intestinal microbiota to counteract colitis.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Leggio+M%22">Leggio M</searchLink>; Department of Medicine 1, University Hospital Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Schramm+S%22">Schramm S</searchLink>; Department of Medicine 1, University Hospital Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.; Deutsches Zentrum Immuntherapie, University Hospital Erlangen, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Dietz+L%22">Dietz L</searchLink>; Department of Medicine 1, University Hospital Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Ocón+B%22">Ocón B</searchLink>; Laboratory of Immunology and Vascular Biology, Department of Pathology, Stanford University School of Medicine and Palo Alto Veterans Medical Center, Stanford, Palo Alto, California, USA.<br /><searchLink fieldCode="AU" term="%22Wirtz+S%22">Wirtz S</searchLink>; Department of Medicine 1, University Hospital Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.; Deutsches Zentrum Immuntherapie, University Hospital Erlangen, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Puertolas+Balint+F%22">Puertolas Balint F</searchLink>; Department of Molecular Biology, Umeå University, Umeå, Sweden.; Laboratory for Molecular Infection Medicine Sweden (MIMS) and Umeå Center for Microbial Research (UCMR), Umeå University, Umeå, Sweden.<br /><searchLink fieldCode="AU" term="%22Yilmaz+B%22">Yilmaz B</searchLink>; Maurice Müller Laboratories, Department for Biomedical Research, University of Bern, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Petzold+J%22">Petzold J</searchLink>; Institute of Clinical Microbiology, Immunology and Hygiene, University Hospital Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Liu+LJ%22">Liu LJ</searchLink>; Department of Medicine 1, University Hospital Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Dedden+M%22">Dedden M</searchLink>; Department of Medicine 1, University Hospital Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Ekici+A%22">Ekici A</searchLink>; Institute of Human Genetics, University Hospital Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Meng+X%22">Meng X</searchLink>; Department of Medicine 1, University Hospital Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Bingham+D%22">Bingham D</searchLink>; Department of Pathology, Stanford University School of Medicine, Stanford, California, USA.<br /><searchLink fieldCode="AU" term="%22Ullrich+KA%22">Ullrich KA</searchLink>; Department of Medicine 1, University Hospital Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Heltmann-Meyer+S%22">Heltmann-Meyer S</searchLink>; Department of Medicine 1, University Hospital Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.; Deutsches Zentrum Immuntherapie, University Hospital Erlangen, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Günther+C%22">Günther C</searchLink>; Department of Medicine 1, University Hospital Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.; Deutsches Zentrum Immuntherapie, University Hospital Erlangen, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Hildner+K%22">Hildner K</searchLink>; Department of Medicine 1, University Hospital Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.; Deutsches Zentrum Immuntherapie, University Hospital Erlangen, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Atreya+R%22">Atreya R</searchLink>; Department of Medicine 1, University Hospital Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.; Deutsches Zentrum Immuntherapie, University Hospital Erlangen, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Atreya+I%22">Atreya I</searchLink>; Department of Medicine 1, University Hospital Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Müller+TM%22">Müller TM</searchLink>; Department of Medicine 1, University Hospital Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.; Deutsches Zentrum Immuntherapie, University Hospital Erlangen, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Gerlach+RG%22">Gerlach RG</searchLink>; Institute of Clinical Microbiology, Immunology and Hygiene, University Hospital Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Schroeder+BO%22">Schroeder BO</searchLink>; Department of Molecular Biology, Umeå University, Umeå, Sweden.; Laboratory for Molecular Infection Medicine Sweden (MIMS) and Umeå Center for Microbial Research (UCMR), Umeå University, Umeå, Sweden.<br /><searchLink fieldCode="AU" term="%22Macpherson+A%22">Macpherson A</searchLink>; Maurice Müller Laboratories, Department for Biomedical Research, University of Bern, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Butcher+EC%22">Butcher EC</searchLink>; Laboratory of Immunology and Vascular Biology, Department of Pathology, Stanford University School of Medicine and Palo Alto Veterans Medical Center, Stanford, Palo Alto, California, USA.<br /><searchLink fieldCode="AU" term="%22Neurath+MF%22">Neurath MF</searchLink>; Department of Medicine 1, University Hospital Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.; Deutsches Zentrum Immuntherapie, University Hospital Erlangen, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Zundler+S%22">Zundler S</searchLink>; Department of Medicine 1, University Hospital Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany sebastian.zundler@uk-erlangen.de.; Deutsches Zentrum Immuntherapie, University Hospital Erlangen, Erlangen, Germany.
– Name: AuthorCorporate
  Label: Corporate Authors
  Group: Au
  Data: <searchLink fieldCode="CA" term="%22TRR241+IBDome+Consortium%22">TRR241 IBDome Consortium</searchLink><br /><searchLink fieldCode="CA" term="%22TRR241+IBCome+Consortium%22">TRR241 IBCome Consortium</searchLink>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%222985108R%22">Gut</searchLink> [Gut] 2026 Jun 25. <i>Date of Electronic Publication: </i>2026 Jun 25.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22British+Medical+Assn%22">British Medical Assn </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>2985108R <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1468-3288 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200175749%22">00175749 </searchLink><i>NLM ISO Abbreviation: </i>Gut <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42209192
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1136/gutjnl-2025-337619
    Languages:
      – Code: eng
        Text: English
    Titles:
      – TitleFull: The endogenous peptide GPR15L shapes the intestinal microbiota to counteract colitis.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Leggio M
      – PersonEntity:
          Name:
            NameFull: Schramm S
      – PersonEntity:
          Name:
            NameFull: Dietz L
      – PersonEntity:
          Name:
            NameFull: Ocón B
      – PersonEntity:
          Name:
            NameFull: Wirtz S
      – PersonEntity:
          Name:
            NameFull: Puertolas Balint F
      – PersonEntity:
          Name:
            NameFull: Yilmaz B
      – PersonEntity:
          Name:
            NameFull: Petzold J
      – PersonEntity:
          Name:
            NameFull: Liu LJ
      – PersonEntity:
          Name:
            NameFull: Dedden M
      – PersonEntity:
          Name:
            NameFull: Ekici A
      – PersonEntity:
          Name:
            NameFull: Meng X
      – PersonEntity:
          Name:
            NameFull: Bingham D
      – PersonEntity:
          Name:
            NameFull: Ullrich KA
      – PersonEntity:
          Name:
            NameFull: Heltmann-Meyer S
      – PersonEntity:
          Name:
            NameFull: Günther C
      – PersonEntity:
          Name:
            NameFull: Hildner K
      – PersonEntity:
          Name:
            NameFull: Atreya R
      – PersonEntity:
          Name:
            NameFull: Atreya I
      – PersonEntity:
          Name:
            NameFull: Müller TM
      – PersonEntity:
          Name:
            NameFull: Gerlach RG
      – PersonEntity:
          Name:
            NameFull: Schroeder BO
      – PersonEntity:
          Name:
            NameFull: Macpherson A
      – PersonEntity:
          Name:
            NameFull: Butcher EC
      – PersonEntity:
          Name:
            NameFull: Neurath MF
      – PersonEntity:
          Name:
            NameFull: Zundler S
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 25
              M: 06
              Text: 2026 Jun 25
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1468-3288
          Titles:
            – TitleFull: Gut
              Type: main
ResultId 1