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KDM6B safeguards mineralized tissue homeostasis from mechanical stress through epigenetic control of PIEZO1-mediated mechanotransduction in the mouse incisor.

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Title: KDM6B safeguards mineralized tissue homeostasis from mechanical stress through epigenetic control of PIEZO1-mediated mechanotransduction in the mouse incisor.
Authors: Meng L; Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, CA, USA., Zhang M; Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, CA, USA., Feng J; Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, CA, USA., Guo T; Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, CA, USA., Hekmat H; Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, CA, USA., Ziaei H; Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, CA, USA., Chen P; Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, CA, USA., Harouni A; Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, CA, USA., Ho TV; Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, CA, USA., Chai Y; Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, CA, USA. ychai@usc.edu.
Source: Bone research [Bone Res] 2026 May 28; Vol. 14 (1). Date of Electronic Publication: 2026 May 28.
Publication Type: Journal Article
Journal Info: Publisher: West China School of Stomatology, Sichuan University Country of Publication: China NLM ID: 101608652 Publication Model: Electronic Cited Medium: Print ISSN: 2095-4700 (Print) Linking ISSN: 20954700 NLM ISO Abbreviation: Bone Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: KDM6B safeguards mineralized tissue homeostasis from mechanical stress through epigenetic control of PIEZO1-mediated mechanotransduction in the mouse incisor.
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  Data: <searchLink fieldCode="AU" term="%22Meng+L%22">Meng L</searchLink>; Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+M%22">Zhang M</searchLink>; Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Feng+J%22">Feng J</searchLink>; Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Guo+T%22">Guo T</searchLink>; Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hekmat+H%22">Hekmat H</searchLink>; Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Ziaei+H%22">Ziaei H</searchLink>; Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Chen+P%22">Chen P</searchLink>; Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Harouni+A%22">Harouni A</searchLink>; Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Ho+TV%22">Ho TV</searchLink>; Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Chai+Y%22">Chai Y</searchLink>; Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, CA, USA. ychai@usc.edu.
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  Data: <searchLink fieldCode="JN" term="%22101608652%22">Bone research</searchLink> [Bone Res] 2026 May 28; Vol. 14 (1). <i>Date of Electronic Publication: </i>2026 May 28.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22West+China+School+of+Stomatology%2C+Sichuan+University%22">West China School of Stomatology, Sichuan University </searchLink><i>Country of Publication: </i>China <i>NLM ID: </i>101608652 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2095-4700 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220954700%22">20954700 </searchLink><i>NLM ISO Abbreviation: </i>Bone Res <i>Subsets: </i>MEDLINE
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        Value: 10.1038/s41413-026-00544-2
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      – Code: eng
        Text: English
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      – TitleFull: KDM6B safeguards mineralized tissue homeostasis from mechanical stress through epigenetic control of PIEZO1-mediated mechanotransduction in the mouse incisor.
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            – D: 28
              M: 05
              Text: 2026 May 28
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              Y: 2026
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