Decoding spontaneous intracerebral hemorrhage: mechanistic breakthroughs and disruptive revolution in pharmacological treatment.

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Title: Decoding spontaneous intracerebral hemorrhage: mechanistic breakthroughs and disruptive revolution in pharmacological treatment.
Authors: Chen Y; Fujian Key Laboratory of Toxicant and Drug Toxicology, undefined, Department of Vascular and Interventional Radiology, Ningde Municipal Hospital of Fujian Medical University, Ningde Normal University, Ningde, China.; Department of Neurosurgery, School of Medicine, Loma Linda University, Loma Linda, CA, USA.; Department of Physiology and Pharmacology, School of Medicine, Loma Linda University, Loma Linda, CA, USA.; Department of Neurosurgery and Anesthesiology, School of Medicine, Loma Linda University, Loma Linda, CA, USA., Wu G; Fujian Key Laboratory of Toxicant and Drug Toxicology, undefined, Department of Vascular and Interventional Radiology, Ningde Municipal Hospital of Fujian Medical University, Ningde Normal University, Ningde, China., Zhang W; School of Anesthesiology, Naval Medical University, Shanghai, China. zwzq001031@smmu.edu.cn., Zou Z; School of Anesthesiology, Naval Medical University, Shanghai, China. zouzui@smmu.edu.cn., Huang L; Department of Neurosurgery and Anesthesiology, School of Medicine, Loma Linda University, Loma Linda, CA, USA. lhuang@llu.edu., Shi H; Faculty of Chinese Medicine and State Key Laboratory of Quality Research in Chinese Medicines, Macau University of Science and Technology, Macau, Macau SAR, China., Wang Q; Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Chen W; Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China., Luo Z; Department of Sports Medicine, Huashan Hospital, Fudan University, Shanghai, China., Zhao Z; Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Wu L; Kunming University of Science and Technology, Chenggong Campus, Kunming, People's Republic of China., Li Z; Clinical Laboratory Center, The People's Hospital of Xinjiang Uygur Autonomous Region, Ürümqi, China., Peng J; Department of Neurosurgery, The Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan, China. pengjianhua@swmu.edu.cn., Chen Y; Neurosurgical Intensive Care Unit, Department of Neurosurgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China. yujiechen6886@foxmail.com., Zhang JH; Department of Neurosurgery, School of Medicine, Loma Linda University, Loma Linda, CA, USA. johnzhang3910@yahoo.com.; Department of Physiology and Pharmacology, School of Medicine, Loma Linda University, Loma Linda, CA, USA. johnzhang3910@yahoo.com.; Department of Neurosurgery and Anesthesiology, School of Medicine, Loma Linda University, Loma Linda, CA, USA. johnzhang3910@yahoo.com.
Source: Experimental & molecular medicine [Exp Mol Med] 2026 May; Vol. 58 (5), pp. 1394-1408. Date of Electronic Publication: 2026 May 28.
Publication Type: Journal Article; Review
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 9607880 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2092-6413 (Electronic) Linking ISSN: 12263613 NLM ISO Abbreviation: Exp Mol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Decoding spontaneous intracerebral hemorrhage: mechanistic breakthroughs and disruptive revolution in pharmacological treatment.
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  Data: <searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; Fujian Key Laboratory of Toxicant and Drug Toxicology, undefined, Department of Vascular and Interventional Radiology, Ningde Municipal Hospital of Fujian Medical University, Ningde Normal University, Ningde, China.; Department of Neurosurgery, School of Medicine, Loma Linda University, Loma Linda, CA, USA.; Department of Physiology and Pharmacology, School of Medicine, Loma Linda University, Loma Linda, CA, USA.; Department of Neurosurgery and Anesthesiology, School of Medicine, Loma Linda University, Loma Linda, CA, USA.<br /><searchLink fieldCode="AU" term="%22Wu+G%22">Wu G</searchLink>; Fujian Key Laboratory of Toxicant and Drug Toxicology, undefined, Department of Vascular and Interventional Radiology, Ningde Municipal Hospital of Fujian Medical University, Ningde Normal University, Ningde, China.<br /><searchLink fieldCode="AU" term="%22Zhang+W%22">Zhang W</searchLink>; School of Anesthesiology, Naval Medical University, Shanghai, China. zwzq001031@smmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Zou+Z%22">Zou Z</searchLink>; School of Anesthesiology, Naval Medical University, Shanghai, China. zouzui@smmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Huang+L%22">Huang L</searchLink>; Department of Neurosurgery and Anesthesiology, School of Medicine, Loma Linda University, Loma Linda, CA, USA. lhuang@llu.edu.<br /><searchLink fieldCode="AU" term="%22Shi+H%22">Shi H</searchLink>; Faculty of Chinese Medicine and State Key Laboratory of Quality Research in Chinese Medicines, Macau University of Science and Technology, Macau, Macau SAR, China.<br /><searchLink fieldCode="AU" term="%22Wang+Q%22">Wang Q</searchLink>; Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Chen+W%22">Chen W</searchLink>; Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Luo+Z%22">Luo Z</searchLink>; Department of Sports Medicine, Huashan Hospital, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Zhao+Z%22">Zhao Z</searchLink>; Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Wu+L%22">Wu L</searchLink>; Kunming University of Science and Technology, Chenggong Campus, Kunming, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Li+Z%22">Li Z</searchLink>; Clinical Laboratory Center, The People's Hospital of Xinjiang Uygur Autonomous Region, Ürümqi, China.<br /><searchLink fieldCode="AU" term="%22Peng+J%22">Peng J</searchLink>; Department of Neurosurgery, The Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan, China. pengjianhua@swmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; Neurosurgical Intensive Care Unit, Department of Neurosurgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China. yujiechen6886@foxmail.com.<br /><searchLink fieldCode="AU" term="%22Zhang+JH%22">Zhang JH</searchLink>; Department of Neurosurgery, School of Medicine, Loma Linda University, Loma Linda, CA, USA. johnzhang3910@yahoo.com.; Department of Physiology and Pharmacology, School of Medicine, Loma Linda University, Loma Linda, CA, USA. johnzhang3910@yahoo.com.; Department of Neurosurgery and Anesthesiology, School of Medicine, Loma Linda University, Loma Linda, CA, USA. johnzhang3910@yahoo.com.
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  Data: <searchLink fieldCode="JN" term="%229607880%22">Experimental & molecular medicine</searchLink> [Exp Mol Med] 2026 May; Vol. 58 (5), pp. 1394-1408. <i>Date of Electronic Publication: </i>2026 May 28.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9607880 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2092-6413 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2212263613%22">12263613 </searchLink><i>NLM ISO Abbreviation: </i>Exp Mol Med <i>Subsets: </i>MEDLINE
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        Value: 10.1038/s12276-026-01733-z
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        Text: English
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        StartPage: 1394
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      – TitleFull: Decoding spontaneous intracerebral hemorrhage: mechanistic breakthroughs and disruptive revolution in pharmacological treatment.
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              Text: 2026 May
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