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Licoisoflavone A potentiates oxaliplatin efficacy in colorectal cancer by dual targeting arginine metabolism of tumor microenvironment and cancer cells.

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Title: Licoisoflavone A potentiates oxaliplatin efficacy in colorectal cancer by dual targeting arginine metabolism of tumor microenvironment and cancer cells.
Authors: Wang L; Jiangsu Clinical Innovation Center for Anorectal Diseases of T.C.M, Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine, Nanjing, 210022, China. wanglu@njucm.edu.cn., Liu QR; Jiangsu Clinical Innovation Center for Anorectal Diseases of T.C.M, Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine, Nanjing, 210022, China., Zhou BW; Jiangsu Clinical Innovation Center for Anorectal Diseases of T.C.M, Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine, Nanjing, 210022, China., Huang CY; Jiangsu Clinical Innovation Center for Anorectal Diseases of T.C.M, Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine, Nanjing, 210022, China., Ding PG; Jiangsu Clinical Innovation Center for Anorectal Diseases of T.C.M, Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine, Nanjing, 210022, China., Dong YJ; Jiangsu Clinical Innovation Center for Anorectal Diseases of T.C.M, Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine, Nanjing, 210022, China., Gong PY; College of Pharmacy, Southwest Minzu University, Chengdu, 610041, China., Chen ZX; Jiangsu Clinical Innovation Center for Anorectal Diseases of T.C.M, Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine, Nanjing, 210022, China., Fan ZM; Jiangsu Clinical Innovation Center for Anorectal Diseases of T.C.M, Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine, Nanjing, 210022, China. fanzm@njucm.edu.cn.
Source: Chinese medicine [Chin Med] 2026 May 28; Vol. 21 (1). Date of Electronic Publication: 2026 May 28.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101265109 Publication Model: Electronic Cited Medium: Print ISSN: 1749-8546 (Print) Linking ISSN: 17498546 NLM ISO Abbreviation: Chin Med Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Licoisoflavone A potentiates oxaliplatin efficacy in colorectal cancer by dual targeting arginine metabolism of tumor microenvironment and cancer cells.
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  Data: <searchLink fieldCode="AU" term="%22Wang+L%22">Wang L</searchLink>; Jiangsu Clinical Innovation Center for Anorectal Diseases of T.C.M, Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine, Nanjing, 210022, China. wanglu@njucm.edu.cn.<br /><searchLink fieldCode="AU" term="%22Liu+QR%22">Liu QR</searchLink>; Jiangsu Clinical Innovation Center for Anorectal Diseases of T.C.M, Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine, Nanjing, 210022, China.<br /><searchLink fieldCode="AU" term="%22Zhou+BW%22">Zhou BW</searchLink>; Jiangsu Clinical Innovation Center for Anorectal Diseases of T.C.M, Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine, Nanjing, 210022, China.<br /><searchLink fieldCode="AU" term="%22Huang+CY%22">Huang CY</searchLink>; Jiangsu Clinical Innovation Center for Anorectal Diseases of T.C.M, Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine, Nanjing, 210022, China.<br /><searchLink fieldCode="AU" term="%22Ding+PG%22">Ding PG</searchLink>; Jiangsu Clinical Innovation Center for Anorectal Diseases of T.C.M, Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine, Nanjing, 210022, China.<br /><searchLink fieldCode="AU" term="%22Dong+YJ%22">Dong YJ</searchLink>; Jiangsu Clinical Innovation Center for Anorectal Diseases of T.C.M, Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine, Nanjing, 210022, China.<br /><searchLink fieldCode="AU" term="%22Gong+PY%22">Gong PY</searchLink>; College of Pharmacy, Southwest Minzu University, Chengdu, 610041, China.<br /><searchLink fieldCode="AU" term="%22Chen+ZX%22">Chen ZX</searchLink>; Jiangsu Clinical Innovation Center for Anorectal Diseases of T.C.M, Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine, Nanjing, 210022, China.<br /><searchLink fieldCode="AU" term="%22Fan+ZM%22">Fan ZM</searchLink>; Jiangsu Clinical Innovation Center for Anorectal Diseases of T.C.M, Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine, Nanjing, 210022, China. fanzm@njucm.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22101265109%22">Chinese medicine</searchLink> [Chin Med] 2026 May 28; Vol. 21 (1). <i>Date of Electronic Publication: </i>2026 May 28.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101265109 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>1749-8546 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217498546%22">17498546 </searchLink><i>NLM ISO Abbreviation: </i>Chin Med <i>Subsets: </i>PubMed not MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42210399
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        Value: 10.1186/s13020-026-01428-7
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      – TitleFull: Licoisoflavone A potentiates oxaliplatin efficacy in colorectal cancer by dual targeting arginine metabolism of tumor microenvironment and cancer cells.
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            – D: 28
              M: 05
              Text: 2026 May 28
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              Y: 2026
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