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Preservation and clonal behavior of extrachromosomal DNA in patient-derived xenograft models of childhood cancers.

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Title: Preservation and clonal behavior of extrachromosomal DNA in patient-derived xenograft models of childhood cancers.
Authors: Kenkre R; Sanford Burnham Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, San Diego, CA, 92037, USA., Chapman OS; Sanford Burnham Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, San Diego, CA, 92037, USA.; Department of Neuro-Oncology, Institute of Brain Sciences, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan., Chow EY; Sanford Burnham Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, San Diego, CA, 92037, USA., Luebeck J; Department of Computer Science and Engineering, University of California San Diego, La Jolla, San Diego, CA, USA., Lo YY; Sanford Burnham Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, San Diego, CA, 92037, USA., Paul M; Rady Children's Hospital San Diego, San Diego, CA, USA.; Department of Pediatrics, University of California San Diego, La Jolla, San Diego, CA, USA., Zhang W; Bioinformatics and Systems Biology Graduate Program, University of California San Diego, La Jolla, San Diego, CA, USA., Mesirov J; School of Medicine, University of California San Diego, La Jolla, San Diego, CA, USA.; Moores Cancer Center, University of California San Diego, San Diego, CA, USA., Bafna V; Department of Computer Science and Engineering, University of California San Diego, La Jolla, San Diego, CA, USA.; Moores Cancer Center, University of California San Diego, San Diego, CA, USA.; Halicioglu Data Science Institute, University of California San Diego, San Diego, CA, USA., Yip K; Sanford Burnham Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, San Diego, CA, 92037, USA., Larson JD; Sanford Burnham Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, San Diego, CA, 92037, USA., Wechsler-Reya RJ; Department of Neurology and Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY, USA., Chavez L; Sanford Burnham Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, San Diego, CA, 92037, USA. lchavez@sbpdiscovery.org.; Department of Medicine, University of California San Diego, La Jolla, San Diego, CA, USA. lchavez@sbpdiscovery.org.; Rady Children's Institute for Genomic Medicine, Rady Children's Hospital and Healthcare Center, San Diego, CA, USA. lchavez@sbpdiscovery.org.
Source: Genome medicine [Genome Med] 2026 May 28. Date of Electronic Publication: 2026 May 28.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101475844 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1756-994X (Electronic) Linking ISSN: 1756994X NLM ISO Abbreviation: Genome Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Preservation and clonal behavior of extrachromosomal DNA in patient-derived xenograft models of childhood cancers.
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  Data: <searchLink fieldCode="AU" term="%22Kenkre+R%22">Kenkre R</searchLink>; Sanford Burnham Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, San Diego, CA, 92037, USA.<br /><searchLink fieldCode="AU" term="%22Chapman+OS%22">Chapman OS</searchLink>; Sanford Burnham Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, San Diego, CA, 92037, USA.; Department of Neuro-Oncology, Institute of Brain Sciences, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.<br /><searchLink fieldCode="AU" term="%22Chow+EY%22">Chow EY</searchLink>; Sanford Burnham Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, San Diego, CA, 92037, USA.<br /><searchLink fieldCode="AU" term="%22Luebeck+J%22">Luebeck J</searchLink>; Department of Computer Science and Engineering, University of California San Diego, La Jolla, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Lo+YY%22">Lo YY</searchLink>; Sanford Burnham Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, San Diego, CA, 92037, USA.<br /><searchLink fieldCode="AU" term="%22Paul+M%22">Paul M</searchLink>; Rady Children's Hospital San Diego, San Diego, CA, USA.; Department of Pediatrics, University of California San Diego, La Jolla, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+W%22">Zhang W</searchLink>; Bioinformatics and Systems Biology Graduate Program, University of California San Diego, La Jolla, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Mesirov+J%22">Mesirov J</searchLink>; School of Medicine, University of California San Diego, La Jolla, San Diego, CA, USA.; Moores Cancer Center, University of California San Diego, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Bafna+V%22">Bafna V</searchLink>; Department of Computer Science and Engineering, University of California San Diego, La Jolla, San Diego, CA, USA.; Moores Cancer Center, University of California San Diego, San Diego, CA, USA.; Halicioglu Data Science Institute, University of California San Diego, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Yip+K%22">Yip K</searchLink>; Sanford Burnham Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, San Diego, CA, 92037, USA.<br /><searchLink fieldCode="AU" term="%22Larson+JD%22">Larson JD</searchLink>; Sanford Burnham Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, San Diego, CA, 92037, USA.<br /><searchLink fieldCode="AU" term="%22Wechsler-Reya+RJ%22">Wechsler-Reya RJ</searchLink>; Department of Neurology and Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Chavez+L%22">Chavez L</searchLink>; Sanford Burnham Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, San Diego, CA, 92037, USA. lchavez@sbpdiscovery.org.; Department of Medicine, University of California San Diego, La Jolla, San Diego, CA, USA. lchavez@sbpdiscovery.org.; Rady Children's Institute for Genomic Medicine, Rady Children's Hospital and Healthcare Center, San Diego, CA, USA. lchavez@sbpdiscovery.org.
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              Text: 2026 May 28
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