Impaired redox adaptation through SLC38A5-dependent glutamine metabolism contributes to melatonin-mediated anoikis sensitivity and metastasis suppression in bone cancer.
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| Title: | Impaired redox adaptation through SLC38A5-dependent glutamine metabolism contributes to melatonin-mediated anoikis sensitivity and metastasis suppression in bone cancer. |
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| Authors: | Nguyen BT; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan., Chen WC; Department of Medicine, MacKay Medical University, New Taipei, Taiwan.; Division of Sports Medicine & Surgery, Department of Orthopedic Surgery, MacKay Memorial Hospital, Taipei, Taiwan., Fong YC; Department of Sports Medicine, College of Health Care, China Medical University, Taichung, Taiwan.; Department of Orthopedic Surgery, China Medical University Hospital, Taichung, Taiwan.; Department of Orthopedic Surgery, China Medical University Beigang Hospital, Yunlin, Taiwan., Ko CY; Department of Orthopedic Surgery, China Medical University Hospital, Taichung, Taiwan., Chen HT; Department of Sports Medicine, College of Health Care, China Medical University, Taichung, Taiwan.; Department of Orthopedic Surgery, China Medical University Hospital, Taichung, Taiwan., Hsu CJ; Department of Orthopedic Surgery, China Medical University Hospital, Taichung, Taiwan.; School of Chinese Medicine, China Medical University, Taichung, Taiwan., Huynh KT; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan.; Center of Molecular Medicine, China Medical University Hospital, Taichung, Taiwan., Huang WC; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan.; Center of Molecular Medicine, China Medical University Hospital, Taichung, Taiwan.; Department of Medical Laboratory Science and Biotechnology, Asia University, Taichung, Taiwan., Yang SF; Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan.; Department of Medical Research, Chung Shan Medical University Hospital, Taichung, Taiwan., Tang CH; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan.; Department of Medical Laboratory Science and Biotechnology, Asia University, Taichung, Taiwan.; Department of Pharmacology, School of Medicine, China Medical University, Taichung, Taiwan.; Chinese Medicine Research Center, China Medical University, Taichung, Taiwan. |
| Source: | International journal of biological sciences [Int J Biol Sci] 2026 May 11; Vol. 22 (10), pp. 5246-5262. Date of Electronic Publication: 2026 May 11 (Print Publication: 2026). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Ivyspring International Country of Publication: Australia NLM ID: 101235568 Publication Model: eCollection Cited Medium: Internet ISSN: 1449-2288 (Electronic) Linking ISSN: 14492288 NLM ISO Abbreviation: Int J Biol Sci Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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