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Integrative transcriptomic analysis unveils FXR as a key regulator of intestinal stemness and inflammation in ulcerative colitis.

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Title: Integrative transcriptomic analysis unveils FXR as a key regulator of intestinal stemness and inflammation in ulcerative colitis.
Authors: Lin H; Jiangsu Key Laboratory of Immunity and Metabolism, Xuzhou Medical University, Xuzhou, Jiangsu 221004, P.R. China., Cheng X; School of Pharmacy, Anhui Medical University, Hefei, Anhui 230032, P.R. China., Ren Y; Department of Clinical Laboratory, Xinyi People's Hospital, Xinyi, Jiangsu 221400, P.R. China., Zhang Y; Jiangsu Province Key Laboratory of Anesthesiology and Brain Science, Xuzhou Medical University, Xuzhou, Jiangsu 221004, P.R. China., Chen W; Department of Gastroenterology, Xuzhou Central Hospital, Southeast University, Xuzhou, Jiangsu 221009, P.R. China., Lu Q; Department of Clinical Laboratory, Xuzhou Central Hospital, Southeast University, Xuzhou, Jiangsu 221009, P.R. China., Tian Y; Department of Clinical Laboratory, Xuzhou Central Hospital, Southeast University, Xuzhou, Jiangsu 221009, P.R. China.
Source: International journal of molecular medicine [Int J Mol Med] 2026 Jul; Vol. 58 (1). Date of Electronic Publication: 2026 May 29.
Publication Type: Journal Article
Journal Info: Publisher: D.A. Spandidos Country of Publication: Greece NLM ID: 9810955 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1791-244X (Electronic) Linking ISSN: 11073756 NLM ISO Abbreviation: Int J Mol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Integrative transcriptomic analysis unveils FXR as a key regulator of intestinal stemness and inflammation in ulcerative colitis.
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  Data: <searchLink fieldCode="AU" term="%22Lin+H%22">Lin H</searchLink>; Jiangsu Key Laboratory of Immunity and Metabolism, Xuzhou Medical University, Xuzhou, Jiangsu 221004, P.R. China.<br /><searchLink fieldCode="AU" term="%22Cheng+X%22">Cheng X</searchLink>; School of Pharmacy, Anhui Medical University, Hefei, Anhui 230032, P.R. China.<br /><searchLink fieldCode="AU" term="%22Ren+Y%22">Ren Y</searchLink>; Department of Clinical Laboratory, Xinyi People's Hospital, Xinyi, Jiangsu 221400, P.R. China.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Jiangsu Province Key Laboratory of Anesthesiology and Brain Science, Xuzhou Medical University, Xuzhou, Jiangsu 221004, P.R. China.<br /><searchLink fieldCode="AU" term="%22Chen+W%22">Chen W</searchLink>; Department of Gastroenterology, Xuzhou Central Hospital, Southeast University, Xuzhou, Jiangsu 221009, P.R. China.<br /><searchLink fieldCode="AU" term="%22Lu+Q%22">Lu Q</searchLink>; Department of Clinical Laboratory, Xuzhou Central Hospital, Southeast University, Xuzhou, Jiangsu 221009, P.R. China.<br /><searchLink fieldCode="AU" term="%22Tian+Y%22">Tian Y</searchLink>; Department of Clinical Laboratory, Xuzhou Central Hospital, Southeast University, Xuzhou, Jiangsu 221009, P.R. China.
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  Data: <searchLink fieldCode="JN" term="%229810955%22">International journal of molecular medicine</searchLink> [Int J Mol Med] 2026 Jul; Vol. 58 (1). <i>Date of Electronic Publication: </i>2026 May 29.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22D%2EA%2E+Spandidos%22">D.A. Spandidos </searchLink><i>Country of Publication: </i>Greece <i>NLM ID: </i>9810955 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1791-244X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2211073756%22">11073756 </searchLink><i>NLM ISO Abbreviation: </i>Int J Mol Med <i>Subsets: </i>MEDLINE
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        Value: 10.3892/ijmm.2026.5871
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        Text: English
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      – TitleFull: Integrative transcriptomic analysis unveils FXR as a key regulator of intestinal stemness and inflammation in ulcerative colitis.
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              Text: 2026 Jul
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