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ABHD2 activity is not required for the non-genomic action of progesterone on human sperm.

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Title: ABHD2 activity is not required for the non-genomic action of progesterone on human sperm.
Authors: Edwards M; Structural Genomics Consortium (SGC), University of Toronto, Toronto, Canada., Amaral A; Nuvisan ICB GMBH, Berlin, Germany., Carter EM; School of Pharmacy and Structural Genomics Consortium, University College London, London, UK., Arnolds O; Structural Genomics Consortium (SGC) and Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden., Vester K; Nuvisan ICB GMBH, Berlin, Germany., Thrun A; Nuvisan ICB GMBH, Berlin, Germany., Wigren E; Structural Genomics Consortium (SGC) and Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden., Homan E; Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden., Ribera P; Chemical Biology Consortium Sweden (CBCS), Science for Life Laboratory, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden., Bentley K; Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden., Haraldsson M; Chemical Biology Consortium Sweden (CBCS), Science for Life Laboratory, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden., Theo-Emegano N; Structural Genomics Consortium (SGC), University of Toronto, Toronto, Canada., Loppnau P; Structural Genomics Consortium (SGC), University of Toronto, Toronto, Canada., Szewczyk MM; Structural Genomics Consortium (SGC), University of Toronto, Toronto, Canada., Cao MA; Structural Genomics Consortium (SGC), University of Toronto, Toronto, Canada., Barsyte-Lovejoy D; Structural Genomics Consortium (SGC), University of Toronto, Toronto, Canada., Dittmar N; Nuvisan ICB GMBH, Berlin, Germany., Hans A; Nuvisan ICB GMBH, Berlin, Germany., Weber M; Nuvisan ICB GMBH, Berlin, Germany., Münchow J; Institute of Pharmaceutical and Medicinal Chemistry, University of Münster, Münster, Germany.; GRK 2515, Chemical Biology of Ion Channels (Chembion), University of Münster, Münster, Germany., Zhu WF; Institute of Pharmaceutical and Medicinal Chemistry, University of Münster, Münster, Germany.; GRK 2515, Chemical Biology of Ion Channels (Chembion), University of Münster, Münster, Germany., Temme L; GRK 2515, Chemical Biology of Ion Channels (Chembion), University of Münster, Münster, Germany.; Institute of Pharmacy, University of Hamburg, Hamburg, Germany., Brenker C; Center of Reproductive Medicine and Andrology, University of Münster, University Hospital Münster, Münster, Germany., Strünker T; GRK 2515, Chemical Biology of Ion Channels (Chembion), University of Münster, Münster, Germany.; Center of Reproductive Medicine and Andrology, University of Münster, University Hospital Münster, Münster, Germany., Sundström M; Structural Genomics Consortium (SGC) and Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden., Todd MH; School of Pharmacy and Structural Genomics Consortium, University College London, London, UK., Edwards AM; Structural Genomics Consortium (SGC), University of Toronto, Toronto, Canada., Lesche R; Nuvisan ICB GMBH, Berlin, Germany., Gileadi O; Structural Genomics Consortium (SGC) and Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden., Tredup C; Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, Frankfurt, Germany.; Structural Genomics Consortium, BMLS, Goethe University Frankfurt, Frankfurt, Germany.
Source: Human reproduction (Oxford, England) [Hum Reprod] 2026 May 29. Date of Electronic Publication: 2026 May 29.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 8701199 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2350 (Electronic) Linking ISSN: 02681161 NLM ISO Abbreviation: Hum Reprod Subsets: MEDLINE
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  Data: ABHD2 activity is not required for the non-genomic action of progesterone on human sperm.
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  Data: <searchLink fieldCode="AU" term="%22Edwards+M%22">Edwards M</searchLink>; Structural Genomics Consortium (SGC), University of Toronto, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Amaral+A%22">Amaral A</searchLink>; Nuvisan ICB GMBH, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Carter+EM%22">Carter EM</searchLink>; School of Pharmacy and Structural Genomics Consortium, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Arnolds+O%22">Arnolds O</searchLink>; Structural Genomics Consortium (SGC) and Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Vester+K%22">Vester K</searchLink>; Nuvisan ICB GMBH, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Thrun+A%22">Thrun A</searchLink>; Nuvisan ICB GMBH, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Wigren+E%22">Wigren E</searchLink>; Structural Genomics Consortium (SGC) and Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Homan+E%22">Homan E</searchLink>; Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Ribera+P%22">Ribera P</searchLink>; Chemical Biology Consortium Sweden (CBCS), Science for Life Laboratory, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Bentley+K%22">Bentley K</searchLink>; Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Haraldsson+M%22">Haraldsson M</searchLink>; Chemical Biology Consortium Sweden (CBCS), Science for Life Laboratory, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Theo-Emegano+N%22">Theo-Emegano N</searchLink>; Structural Genomics Consortium (SGC), University of Toronto, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Loppnau+P%22">Loppnau P</searchLink>; Structural Genomics Consortium (SGC), University of Toronto, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Szewczyk+MM%22">Szewczyk MM</searchLink>; Structural Genomics Consortium (SGC), University of Toronto, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Cao+MA%22">Cao MA</searchLink>; Structural Genomics Consortium (SGC), University of Toronto, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Barsyte-Lovejoy+D%22">Barsyte-Lovejoy D</searchLink>; Structural Genomics Consortium (SGC), University of Toronto, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Dittmar+N%22">Dittmar N</searchLink>; Nuvisan ICB GMBH, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Hans+A%22">Hans A</searchLink>; Nuvisan ICB GMBH, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Weber+M%22">Weber M</searchLink>; Nuvisan ICB GMBH, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Münchow+J%22">Münchow J</searchLink>; Institute of Pharmaceutical and Medicinal Chemistry, University of Münster, Münster, Germany.; GRK 2515, Chemical Biology of Ion Channels (Chembion), University of Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Zhu+WF%22">Zhu WF</searchLink>; Institute of Pharmaceutical and Medicinal Chemistry, University of Münster, Münster, Germany.; GRK 2515, Chemical Biology of Ion Channels (Chembion), University of Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Temme+L%22">Temme L</searchLink>; GRK 2515, Chemical Biology of Ion Channels (Chembion), University of Münster, Münster, Germany.; Institute of Pharmacy, University of Hamburg, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Brenker+C%22">Brenker C</searchLink>; Center of Reproductive Medicine and Andrology, University of Münster, University Hospital Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Strünker+T%22">Strünker T</searchLink>; GRK 2515, Chemical Biology of Ion Channels (Chembion), University of Münster, Münster, Germany.; Center of Reproductive Medicine and Andrology, University of Münster, University Hospital Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Sundström+M%22">Sundström M</searchLink>; Structural Genomics Consortium (SGC) and Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Todd+MH%22">Todd MH</searchLink>; School of Pharmacy and Structural Genomics Consortium, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Edwards+AM%22">Edwards AM</searchLink>; Structural Genomics Consortium (SGC), University of Toronto, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Lesche+R%22">Lesche R</searchLink>; Nuvisan ICB GMBH, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Gileadi+O%22">Gileadi O</searchLink>; Structural Genomics Consortium (SGC) and Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Tredup+C%22">Tredup C</searchLink>; Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, Frankfurt, Germany.; Structural Genomics Consortium, BMLS, Goethe University Frankfurt, Frankfurt, Germany.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8701199 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1460-2350 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2202681161%22">02681161 </searchLink><i>NLM ISO Abbreviation: </i>Hum Reprod <i>Subsets: </i>MEDLINE
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