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Radiotherapeutic management of metastatic brain disease: a two-decade meta-analysis of tumor control and neurocognitive outcomes with SRS alone versus SRS plus WBRT.

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Title: Radiotherapeutic management of metastatic brain disease: a two-decade meta-analysis of tumor control and neurocognitive outcomes with SRS alone versus SRS plus WBRT.
Authors: Pichardo-Rojas PS; Department of Neurosurgery, The Mount Sinai Hospital, New York, NY, USA., Garcia-Torrico F; Universidad Mayor de San Andrés, La Paz, Bolivia., Andrade-Arbaiza EA; Universidad de El Salvador, Facultad Multidisciplinaria Oriental, San Miguel, El Salvador., Calderón Magdaleno LF; Facultad de Ciencias, Universidad Nacional Autónoma de México, Ciudad de México, México., Ortiz A; Universidad Autónoma de Tamaulipas, Facultad de Medicina Humana de Matamoros, Tamaulipas, México., Rodriguez Romero MA; Universidad Autónoma del Estado de México, Toluca, Estado de México, México., Palomino-Ojeda C; Facultad de Ciencias de la Salud, Universidad Espíritu Santo, Samborondón, Ecuador., Bekal M; Vivian L. Smith Department of Neurosurgery, McGovern Medical School at the University of Texas Health Science Center at Houston, Houston, TX, USA., Shah AH; Department of Neurosurgery, Miller School of Medicine, University of Miami, Miami, FL, USA., Sheehan J; Department of Neurosurgery, University of Virginia School of Medicine, Charlottesville, VA, USA., Esquenazi Y; Vivian L. Smith Department of Neurosurgery, McGovern Medical School at the University of Texas Health Science Center at Houston, Houston, TX, USA. Yoshua.EsquenaziLevy@uth.tmc.edu.; Vivian L. Smith Department of Neurosurgery and Center for Precision Health, The University of Texas Health Science Center at Houston - McGovern Medical School, 6400 Fannin Street, Suite # 2800, Houston, TX, 77030, USA. Yoshua.EsquenaziLevy@uth.tmc.edu.
Source: Journal of neuro-oncology [J Neurooncol] 2026 May 29; Vol. 178 (1). Date of Electronic Publication: 2026 May 29.
Publication Type: Comparative Study; Journal Article; Meta-Analysis
Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 8309335 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-7373 (Electronic) Linking ISSN: 0167594X NLM ISO Abbreviation: J Neurooncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Radiotherapeutic management of metastatic brain disease: a two-decade meta-analysis of tumor control and neurocognitive outcomes with SRS alone versus SRS plus WBRT.
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  Data: <searchLink fieldCode="AU" term="%22Pichardo-Rojas+PS%22">Pichardo-Rojas PS</searchLink>; Department of Neurosurgery, The Mount Sinai Hospital, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Garcia-Torrico+F%22">Garcia-Torrico F</searchLink>; Universidad Mayor de San Andrés, La Paz, Bolivia.<br /><searchLink fieldCode="AU" term="%22Andrade-Arbaiza+EA%22">Andrade-Arbaiza EA</searchLink>; Universidad de El Salvador, Facultad Multidisciplinaria Oriental, San Miguel, El Salvador.<br /><searchLink fieldCode="AU" term="%22Calderón+Magdaleno+LF%22">Calderón Magdaleno LF</searchLink>; Facultad de Ciencias, Universidad Nacional Autónoma de México, Ciudad de México, México.<br /><searchLink fieldCode="AU" term="%22Ortiz+A%22">Ortiz A</searchLink>; Universidad Autónoma de Tamaulipas, Facultad de Medicina Humana de Matamoros, Tamaulipas, México.<br /><searchLink fieldCode="AU" term="%22Rodriguez+Romero+MA%22">Rodriguez Romero MA</searchLink>; Universidad Autónoma del Estado de México, Toluca, Estado de México, México.<br /><searchLink fieldCode="AU" term="%22Palomino-Ojeda+C%22">Palomino-Ojeda C</searchLink>; Facultad de Ciencias de la Salud, Universidad Espíritu Santo, Samborondón, Ecuador.<br /><searchLink fieldCode="AU" term="%22Bekal+M%22">Bekal M</searchLink>; Vivian L. Smith Department of Neurosurgery, McGovern Medical School at the University of Texas Health Science Center at Houston, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Shah+AH%22">Shah AH</searchLink>; Department of Neurosurgery, Miller School of Medicine, University of Miami, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Sheehan+J%22">Sheehan J</searchLink>; Department of Neurosurgery, University of Virginia School of Medicine, Charlottesville, VA, USA.<br /><searchLink fieldCode="AU" term="%22Esquenazi+Y%22">Esquenazi Y</searchLink>; Vivian L. Smith Department of Neurosurgery, McGovern Medical School at the University of Texas Health Science Center at Houston, Houston, TX, USA. Yoshua.EsquenaziLevy@uth.tmc.edu.; Vivian L. Smith Department of Neurosurgery and Center for Precision Health, The University of Texas Health Science Center at Houston - McGovern Medical School, 6400 Fannin Street, Suite # 2800, Houston, TX, 77030, USA. Yoshua.EsquenaziLevy@uth.tmc.edu.
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  Data: <searchLink fieldCode="JN" term="%228309335%22">Journal of neuro-oncology</searchLink> [J Neurooncol] 2026 May 29; Vol. 178 (1). <i>Date of Electronic Publication: </i>2026 May 29.
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