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Surface-engineered heparin- and methoxy poly(ethylene glycol)-modified gelatin microspheres for enhanced extracellular vesicle enrichment.

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Title: Surface-engineered heparin- and methoxy poly(ethylene glycol)-modified gelatin microspheres for enhanced extracellular vesicle enrichment.
Authors: Tai YT; Graduate Institute of Applied Science and Technology, National Taiwan University of Science and Technology, Taipei 106, Taiwan., Cheng YT; Graduate Institute of Applied Science and Technology, National Taiwan University of Science and Technology, Taipei 106, Taiwan., Li DA; Graduate Institute of Applied Science and Technology, National Taiwan University of Science and Technology, Taipei 106, Taiwan., Chang YT; S&T BioMed Co., Ltd., Hsinchu County, Taiwan., Liu YC; Molecular Medicine Research Center, Chang Gung University, Taoyuan City, Taiwan., Huang CC; Biomedical Platform and Incubation Services Division, National Institutes of Applied Research, National Center for Instrumentation Research, Hsinchu, Taiwan., Wang JS; Biomedical Platform and Incubation Services Division, National Institutes of Applied Research, National Center for Instrumentation Research, Hsinchu, Taiwan., Lin SY; Biomedical Technology and Device Research Center, Industrial Technology Research Institute, Hsinchu, 310, Taiwan., Yu JS; Department of Otolaryngology-Head and Neck Surgery, Chang Gung Memorial Hospital at Linkou, Taoyuan City, Taiwan., Tsai HC; Graduate Institute of Applied Science and Technology, National Taiwan University of Science and Technology, Taipei 106, Taiwan; Advanced Membrane Materials Center, National Taiwan University of Science and Technology, Taipei, 106, Taiwan; R&D Center for Membrane Technology, Chung Yuan Christian University, Chungli, Taoyuan 320, Taiwan. Electronic address: h.c.tsai@mail.ntust.edu.tw.
Source: International journal of biological macromolecules [Int J Biol Macromol] 2026 Jul; Vol. 370, pp. 152782. Date of Electronic Publication: 2026 May 28.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Surface-engineered heparin- and methoxy poly(ethylene glycol)-modified gelatin microspheres for enhanced extracellular vesicle enrichment.
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  Data: <searchLink fieldCode="AU" term="%22Tai+YT%22">Tai YT</searchLink>; Graduate Institute of Applied Science and Technology, National Taiwan University of Science and Technology, Taipei 106, Taiwan.<br /><searchLink fieldCode="AU" term="%22Cheng+YT%22">Cheng YT</searchLink>; Graduate Institute of Applied Science and Technology, National Taiwan University of Science and Technology, Taipei 106, Taiwan.<br /><searchLink fieldCode="AU" term="%22Li+DA%22">Li DA</searchLink>; Graduate Institute of Applied Science and Technology, National Taiwan University of Science and Technology, Taipei 106, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chang+YT%22">Chang YT</searchLink>; S&T BioMed Co., Ltd., Hsinchu County, Taiwan.<br /><searchLink fieldCode="AU" term="%22Liu+YC%22">Liu YC</searchLink>; Molecular Medicine Research Center, Chang Gung University, Taoyuan City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Huang+CC%22">Huang CC</searchLink>; Biomedical Platform and Incubation Services Division, National Institutes of Applied Research, National Center for Instrumentation Research, Hsinchu, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wang+JS%22">Wang JS</searchLink>; Biomedical Platform and Incubation Services Division, National Institutes of Applied Research, National Center for Instrumentation Research, Hsinchu, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+SY%22">Lin SY</searchLink>; Biomedical Technology and Device Research Center, Industrial Technology Research Institute, Hsinchu, 310, Taiwan.<br /><searchLink fieldCode="AU" term="%22Yu+JS%22">Yu JS</searchLink>; Department of Otolaryngology-Head and Neck Surgery, Chang Gung Memorial Hospital at Linkou, Taoyuan City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Tsai+HC%22">Tsai HC</searchLink>; Graduate Institute of Applied Science and Technology, National Taiwan University of Science and Technology, Taipei 106, Taiwan; Advanced Membrane Materials Center, National Taiwan University of Science and Technology, Taipei, 106, Taiwan; R&D Center for Membrane Technology, Chung Yuan Christian University, Chungli, Taoyuan 320, Taiwan. Electronic address: h.c.tsai@mail.ntust.edu.tw.
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  Data: <searchLink fieldCode="JN" term="%227909578%22">International journal of biological macromolecules</searchLink> [Int J Biol Macromol] 2026 Jul; Vol. 370, pp. 152782. <i>Date of Electronic Publication: </i>2026 May 28.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>7909578 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1879-0003 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201418130%22">01418130 </searchLink><i>NLM ISO Abbreviation: </i>Int J Biol Macromol <i>Subsets: </i>MEDLINE; In Process
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      – Type: doi
        Value: 10.1016/j.ijbiomac.2026.152782
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      – Code: eng
        Text: English
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        StartPage: 152782
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      – TitleFull: Surface-engineered heparin- and methoxy poly(ethylene glycol)-modified gelatin microspheres for enhanced extracellular vesicle enrichment.
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            – D: 01
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              Text: 2026 Jul
              Type: published
              Y: 2026
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