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NLRP1 inflammasome activation in skin equivalents reveals mechanistic insights into the roles of keratinocytes in psoriasis.

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Title: NLRP1 inflammasome activation in skin equivalents reveals mechanistic insights into the roles of keratinocytes in psoriasis.
Authors: Di Filippo M; Department of Dermatology, University Hospital Zurich, Zurich, Switzerland., Karakaya T; Department of Dermatology, University Hospital Zurich, Zurich, Switzerland., Slaufova M; Department of Dermatology, University Hospital Zurich, Zurich, Switzerland., Cheng PF; Department of Dermatology, University Hospital Zurich, Zurich, Switzerland., Hennig P; Department of Dermatology, University Hospital Zurich, Zurich, Switzerland., Boukamp P; DKFZ, Heidelberg, Germany., Pascolo S; Department of Dermatology, University Hospital Zurich, Zurich, Switzerland.; Faculty of Medicine, University of Zurich, Zurich, Switzerland., Maul JT; Department of Dermatology, University Hospital Zurich, Zurich, Switzerland., Kolm I; Department of Dermatology, University Hospital Zurich, Zurich, Switzerland., Levesque MP; Department of Dermatology, University Hospital Zurich, Zurich, Switzerland.; Faculty of Medicine, University of Zurich, Zurich, Switzerland., Kündig T; Department of Dermatology, University Hospital Zurich, Zurich, Switzerland.; Faculty of Medicine, University of Zurich, Zurich, Switzerland., Beer HD; Department of Dermatology, University Hospital Zurich, Zurich, Switzerland. Hans-Dietmar.Beer@usz.ch.; Faculty of Medicine, University of Zurich, Zurich, Switzerland. Hans-Dietmar.Beer@usz.ch.
Source: Cell death & disease [Cell Death Dis] 2026 May 30. Date of Electronic Publication: 2026 May 30.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Di+Filippo+M%22">Di Filippo M</searchLink>; Department of Dermatology, University Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Karakaya+T%22">Karakaya T</searchLink>; Department of Dermatology, University Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Slaufova+M%22">Slaufova M</searchLink>; Department of Dermatology, University Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Cheng+PF%22">Cheng PF</searchLink>; Department of Dermatology, University Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Hennig+P%22">Hennig P</searchLink>; Department of Dermatology, University Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Boukamp+P%22">Boukamp P</searchLink>; DKFZ, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Pascolo+S%22">Pascolo S</searchLink>; Department of Dermatology, University Hospital Zurich, Zurich, Switzerland.; Faculty of Medicine, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Maul+JT%22">Maul JT</searchLink>; Department of Dermatology, University Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Kolm+I%22">Kolm I</searchLink>; Department of Dermatology, University Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Levesque+MP%22">Levesque MP</searchLink>; Department of Dermatology, University Hospital Zurich, Zurich, Switzerland.; Faculty of Medicine, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Kündig+T%22">Kündig T</searchLink>; Department of Dermatology, University Hospital Zurich, Zurich, Switzerland.; Faculty of Medicine, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Beer+HD%22">Beer HD</searchLink>; Department of Dermatology, University Hospital Zurich, Zurich, Switzerland. Hans-Dietmar.Beer@usz.ch.; Faculty of Medicine, University of Zurich, Zurich, Switzerland. Hans-Dietmar.Beer@usz.ch.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101524092 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-4889 (Electronic) <i>NLM ISO Abbreviation: </i>Cell Death Dis <i>Subsets: </i>MEDLINE
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              Text: 2026 May 30
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