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Dual activation of MC3R and MC4R drives weight loss and reduces food intake in male primates with obesity.

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Title: Dual activation of MC3R and MC4R drives weight loss and reduces food intake in male primates with obesity.
Authors: Seiler JL; Endevica Bio, Northbrook, IL, USA., Impastato AC; Endevica Bio, Northbrook, IL, USA., Zhang EX; Endevica Bio, Northbrook, IL, USA., Kelley KJ; Endevica Bio, Northbrook, IL, USA., Bennett TL; Endevica Bio, Northbrook, IL, USA., Studnitzer B; Endevica Bio, Northbrook, IL, USA., Prindle CR; Endevica Bio, Northbrook, IL, USA., Rajewski BH; Endevica Bio, Northbrook, IL, USA., Badeau BA; Endevica Bio, Northbrook, IL, USA., Jiang X; WuXi Apptec, Shanghai, China., Potterfield R; Endevica Bio, Northbrook, IL, USA., Delev JY; Endevica Bio, Northbrook, IL, USA. jordan@endevicabio.com., Marks DL; Endevica Bio, Northbrook, IL, USA. dan@endevicabio.com.
Source: Nature communications [Nat Commun] 2026 May 29; Vol. 17 (1). Date of Electronic Publication: 2026 May 29.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Dual activation of MC3R and MC4R drives weight loss and reduces food intake in male primates with obesity.
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  Data: <searchLink fieldCode="AU" term="%22Seiler+JL%22">Seiler JL</searchLink>; Endevica Bio, Northbrook, IL, USA.<br /><searchLink fieldCode="AU" term="%22Impastato+AC%22">Impastato AC</searchLink>; Endevica Bio, Northbrook, IL, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+EX%22">Zhang EX</searchLink>; Endevica Bio, Northbrook, IL, USA.<br /><searchLink fieldCode="AU" term="%22Kelley+KJ%22">Kelley KJ</searchLink>; Endevica Bio, Northbrook, IL, USA.<br /><searchLink fieldCode="AU" term="%22Bennett+TL%22">Bennett TL</searchLink>; Endevica Bio, Northbrook, IL, USA.<br /><searchLink fieldCode="AU" term="%22Studnitzer+B%22">Studnitzer B</searchLink>; Endevica Bio, Northbrook, IL, USA.<br /><searchLink fieldCode="AU" term="%22Prindle+CR%22">Prindle CR</searchLink>; Endevica Bio, Northbrook, IL, USA.<br /><searchLink fieldCode="AU" term="%22Rajewski+BH%22">Rajewski BH</searchLink>; Endevica Bio, Northbrook, IL, USA.<br /><searchLink fieldCode="AU" term="%22Badeau+BA%22">Badeau BA</searchLink>; Endevica Bio, Northbrook, IL, USA.<br /><searchLink fieldCode="AU" term="%22Jiang+X%22">Jiang X</searchLink>; WuXi Apptec, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Potterfield+R%22">Potterfield R</searchLink>; Endevica Bio, Northbrook, IL, USA.<br /><searchLink fieldCode="AU" term="%22Delev+JY%22">Delev JY</searchLink>; Endevica Bio, Northbrook, IL, USA. jordan@endevicabio.com.<br /><searchLink fieldCode="AU" term="%22Marks+DL%22">Marks DL</searchLink>; Endevica Bio, Northbrook, IL, USA. dan@endevicabio.com.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2026 May 29; Vol. 17 (1). <i>Date of Electronic Publication: </i>2026 May 29.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101528555 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-1723 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220411723%22">20411723 </searchLink><i>NLM ISO Abbreviation: </i>Nat Commun <i>Subsets: </i>MEDLINE
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