Large-scale analysis of temporal gene expression variation in peripheral blood.
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| Title: | Large-scale analysis of temporal gene expression variation in peripheral blood. |
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| Authors: | Mishra N; Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel and University Hospital Center Schleswig-Holstein, Kiel, Germany., Kimmig F; Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel and University Hospital Center Schleswig-Holstein, Kiel, Germany., Vandeputte D; Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute, KU Leuven, Leuven, Belgium.; Center for Microbiology, VIB-KU Leuven, Leuven, Belgium.; AIMS lab, Faculty of Medicine and Pharmacy, Vrije Universiteit Brussel, Brussels, Belgium.; Laboratory of Microbiology, Department of Biochemistry and Microbiology, Ghent University, Ghent, Belgium., Talevi V; Population Health Sciences, German Centre for Neurodegenerative Diseases (DZNE), Bonn, Germany., De Commer L; Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute, KU Leuven, Leuven, Belgium.; Center for Microbiology, VIB-KU Leuven, Leuven, Belgium., Verspecht C; Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute, KU Leuven, Leuven, Belgium.; Center for Microbiology, VIB-KU Leuven, Leuven, Belgium., Vich Vila A; Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute, KU Leuven, Leuven, Belgium.; Center for Microbiology, VIB-KU Leuven, Leuven, Belgium., El-Sayed Moustafa JS; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Kreft L; VIB Bioinformatics Core, VIB, Ghent, Belgium., Botzki A; VIB Technology Training, VIB, Ghent, Belgium., El Darzi Y; Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute, KU Leuven, Leuven, Belgium.; Center for Microbiology, VIB-KU Leuven, Leuven, Belgium., Proost S; Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute, KU Leuven, Leuven, Belgium.; Center for Microbiology, VIB-KU Leuven, Leuven, Belgium., Devolder L; Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute, KU Leuven, Leuven, Belgium.; Center for Microbiology, VIB-KU Leuven, Leuven, Belgium., Wang D; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Bernardes JP; Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel and University Hospital Center Schleswig-Holstein, Kiel, Germany., Aziz NA; Population Health Sciences, German Centre for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Centre of Neurology, Clinic for Parkinson, Sleep and Movement Disorders, University Hospital Bonn, University of Bonn, Bonn, Germany.; Institute for Medical Biometry, Informatics and Epidemiology (IMBIE), University Hospital Bonn, University of Bonn, Bonn, Germany., Franke A; Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel and University Hospital Center Schleswig-Holstein, Kiel, Germany., Schreiber S; Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel and University Hospital Center Schleswig-Holstein, Kiel, Germany.; Department of General Internal Medicine I, University Hospital Schleswig-Holstein, Kiel, Germany., Dermitzakis ET; Institute of Genetics and Genomics of Geneva (iGE3), University of Geneva, Geneva, Switzerland.; Department of Genetic Medicine and Development, Faculty of Medicine, University of Geneva, Geneva, Switzerland.; Swiss Institute of Bioinformatics, Geneva, Switzerland., Vieira-Silva S; Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute, KU Leuven, Leuven, Belgium.; Institute of Medical Microbiology and Hygiene and Research Centre for Immunotherapy (FZI), University Medical Centre of the Johannes Gutenberg University, Mainz, Germany.; Institute of Molecular Biology (IMB), Mainz, Germany.; Institute for Quantitative and Computational Biosciences (IQCB), Johannes Gutenberg University, Mainz, Germany., Falony G; Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute, KU Leuven, Leuven, Belgium.; Institute of Medical Microbiology and Hygiene and Research Centre for Immunotherapy (FZI), University Medical Centre of the Johannes Gutenberg University, Mainz, Germany.; Host-Microbe Interactomics Group, Wageningen University, Wageningen, The Netherlands., Small KS; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Breteler MMB; Population Health Sciences, German Centre for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Institute for Medical Biometry, Informatics and Epidemiology (IMBIE), University Hospital Bonn, University of Bonn, Bonn, Germany., Schultze JL; Systems Medicine, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Genomics & Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.; PRECISE Platform for Single Cell Genomics and Epigenomics, DZNE and University of Bonn, Bonn, Germany., Raes J; Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute, KU Leuven, Leuven, Belgium. jeroen.raes@kuleuven.be.; Center for Microbiology, VIB-KU Leuven, Leuven, Belgium. jeroen.raes@kuleuven.be., Rosenstiel P; Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel and University Hospital Center Schleswig-Holstein, Kiel, Germany. p.rosenstiel@mucosa.de. |
| Corporate Authors: | SYSCID consortium |
| Source: | Nature communications [Nat Commun] 2026 May 29. Date of Electronic Publication: 2026 May 29. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42215465 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Large-scale analysis of temporal gene expression variation in peripheral blood. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Mishra+N%22">Mishra N</searchLink>; Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel and University Hospital Center Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Kimmig+F%22">Kimmig F</searchLink>; Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel and University Hospital Center Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Vandeputte+D%22">Vandeputte D</searchLink>; Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute, KU Leuven, Leuven, Belgium.; Center for Microbiology, VIB-KU Leuven, Leuven, Belgium.; AIMS lab, Faculty of Medicine and Pharmacy, Vrije Universiteit Brussel, Brussels, Belgium.; Laboratory of Microbiology, Department of Biochemistry and Microbiology, Ghent University, Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Talevi+V%22">Talevi V</searchLink>; Population Health Sciences, German Centre for Neurodegenerative Diseases (DZNE), Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22De+Commer+L%22">De Commer L</searchLink>; Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute, KU Leuven, Leuven, Belgium.; Center for Microbiology, VIB-KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Verspecht+C%22">Verspecht C</searchLink>; Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute, KU Leuven, Leuven, Belgium.; Center for Microbiology, VIB-KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Vich+Vila+A%22">Vich Vila A</searchLink>; Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute, KU Leuven, Leuven, Belgium.; Center for Microbiology, VIB-KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22El-Sayed+Moustafa+JS%22">El-Sayed Moustafa JS</searchLink>; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Kreft+L%22">Kreft L</searchLink>; VIB Bioinformatics Core, VIB, Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Botzki+A%22">Botzki A</searchLink>; VIB Technology Training, VIB, Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22El+Darzi+Y%22">El Darzi Y</searchLink>; Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute, KU Leuven, Leuven, Belgium.; Center for Microbiology, VIB-KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Proost+S%22">Proost S</searchLink>; Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute, KU Leuven, Leuven, Belgium.; Center for Microbiology, VIB-KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Devolder+L%22">Devolder L</searchLink>; Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute, KU Leuven, Leuven, Belgium.; Center for Microbiology, VIB-KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Wang+D%22">Wang D</searchLink>; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Bernardes+JP%22">Bernardes JP</searchLink>; Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel and University Hospital Center Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Aziz+NA%22">Aziz NA</searchLink>; Population Health Sciences, German Centre for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Centre of Neurology, Clinic for Parkinson, Sleep and Movement Disorders, University Hospital Bonn, University of Bonn, Bonn, Germany.; Institute for Medical Biometry, Informatics and Epidemiology (IMBIE), University Hospital Bonn, University of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Franke+A%22">Franke A</searchLink>; Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel and University Hospital Center Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Schreiber+S%22">Schreiber S</searchLink>; Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel and University Hospital Center Schleswig-Holstein, Kiel, Germany.; Department of General Internal Medicine I, University Hospital Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Dermitzakis+ET%22">Dermitzakis ET</searchLink>; Institute of Genetics and Genomics of Geneva (iGE3), University of Geneva, Geneva, Switzerland.; Department of Genetic Medicine and Development, Faculty of Medicine, University of Geneva, Geneva, Switzerland.; Swiss Institute of Bioinformatics, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Vieira-Silva+S%22">Vieira-Silva S</searchLink>; Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute, KU Leuven, Leuven, Belgium.; Institute of Medical Microbiology and Hygiene and Research Centre for Immunotherapy (FZI), University Medical Centre of the Johannes Gutenberg University, Mainz, Germany.; Institute of Molecular Biology (IMB), Mainz, Germany.; Institute for Quantitative and Computational Biosciences (IQCB), Johannes Gutenberg University, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Falony+G%22">Falony G</searchLink>; Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute, KU Leuven, Leuven, Belgium.; Institute of Medical Microbiology and Hygiene and Research Centre for Immunotherapy (FZI), University Medical Centre of the Johannes Gutenberg University, Mainz, Germany.; Host-Microbe Interactomics Group, Wageningen University, Wageningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Small+KS%22">Small KS</searchLink>; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Breteler+MMB%22">Breteler MMB</searchLink>; Population Health Sciences, German Centre for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Institute for Medical Biometry, Informatics and Epidemiology (IMBIE), University Hospital Bonn, University of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Schultze+JL%22">Schultze JL</searchLink>; Systems Medicine, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Genomics & Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.; PRECISE Platform for Single Cell Genomics and Epigenomics, DZNE and University of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Raes+J%22">Raes J</searchLink>; Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute, KU Leuven, Leuven, Belgium. jeroen.raes@kuleuven.be.; Center for Microbiology, VIB-KU Leuven, Leuven, Belgium. jeroen.raes@kuleuven.be.<br /><searchLink fieldCode="AU" term="%22Rosenstiel+P%22">Rosenstiel P</searchLink>; Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel and University Hospital Center Schleswig-Holstein, Kiel, Germany. p.rosenstiel@mucosa.de. – Name: AuthorCorporate Label: Corporate Authors Group: Au Data: <searchLink fieldCode="CA" term="%22SYSCID+consortium%22">SYSCID consortium</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2026 May 29. <i>Date of Electronic Publication: </i>2026 May 29. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101528555 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-1723 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220411723%22">20411723 </searchLink><i>NLM ISO Abbreviation: </i>Nat Commun <i>Subsets: </i>MEDLINE |
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