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Integrated clinical, genomic and functional characterization of a novel ALK variant in neuroblastoma.

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Title: Integrated clinical, genomic and functional characterization of a novel ALK variant in neuroblastoma.
Authors: Cañadas García A; Division of Cellular and Molecular Pathology, Department of Pathology, University of Cambridge, Cambridge, CB20QQ, UK., Thombare K; Department of Laboratory Medicine, Institute of Biomedicine, University of Gothenburg, Sweden; Department of Clinical Chemistry, Sahlgrenska University Hospital, Gothenburg, Region Västra Götaland, Sweden., Jahangiri L; Division of Cellular and Molecular Pathology, Department of Pathology, University of Cambridge, Cambridge, CB20QQ, UK., Burman AR; Division of Cellular and Molecular Pathology, Department of Pathology, University of Cambridge, Cambridge, CB20QQ, UK., Ducray SP; Division of Cellular and Molecular Pathology, Department of Pathology, University of Cambridge, Cambridge, CB20QQ, UK., Burke GAA; CRUK Clinical Trials Unit, University of Birmingham, Birmingham, UK., Goodman A; Newcastle Genetics Laboratory, Newcastle Upon Tyne Hospitals NHS Trust, Newcastle Upon Tyne, UK., Woodward ER; Department of Paediatric Oncology, Royal Manchester Children's Hospital, Division of Cancer Sciences, University of Manchester & Manchester Centre for Genomic Medicine, Manchester, M13 9WL, UK., Cheesman E; Department of Paediatric Oncology, Royal Manchester Children's Hospital, Division of Cancer Sciences, University of Manchester & Manchester Centre for Genomic Medicine, Manchester, M13 9WL, UK., Penn A; Department of Paediatric Oncology, Royal Manchester Children's Hospital, Division of Cancer Sciences, University of Manchester & Manchester Centre for Genomic Medicine, Manchester, M13 9WL, UK., Mondal T; Department of Laboratory Medicine, Institute of Biomedicine, University of Gothenburg, Sweden; Department of Clinical Chemistry, Sahlgrenska University Hospital, Gothenburg, Region Västra Götaland, Sweden., Turner SD; Division of Cellular and Molecular Pathology, Department of Pathology, University of Cambridge, Cambridge, CB20QQ, UK; European Research Initiative for ALK Related Malignancies (ERIA), UK; Faculty of Medicine, Masaryk University, Brno, Czech Republic. Electronic address: sdt36@cam.ac.uk., Pucci P; Division of Cellular and Molecular Pathology, Department of Pathology, University of Cambridge, Cambridge, CB20QQ, UK. Electronic address: pp504@cam.ac.uk.
Source: Cancer letters [Cancer Lett] 2026 Sep 28; Vol. 656, pp. 218624. Date of Electronic Publication: 2026 May 29.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7980 (Electronic) Linking ISSN: 03043835 NLM ISO Abbreviation: Cancer Lett Subsets: MEDLINE; In Process
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  Data: <searchLink fieldCode="AU" term="%22Cañadas+García+A%22">Cañadas García A</searchLink>; Division of Cellular and Molecular Pathology, Department of Pathology, University of Cambridge, Cambridge, CB20QQ, UK.<br /><searchLink fieldCode="AU" term="%22Thombare+K%22">Thombare K</searchLink>; Department of Laboratory Medicine, Institute of Biomedicine, University of Gothenburg, Sweden; Department of Clinical Chemistry, Sahlgrenska University Hospital, Gothenburg, Region Västra Götaland, Sweden.<br /><searchLink fieldCode="AU" term="%22Jahangiri+L%22">Jahangiri L</searchLink>; Division of Cellular and Molecular Pathology, Department of Pathology, University of Cambridge, Cambridge, CB20QQ, UK.<br /><searchLink fieldCode="AU" term="%22Burman+AR%22">Burman AR</searchLink>; Division of Cellular and Molecular Pathology, Department of Pathology, University of Cambridge, Cambridge, CB20QQ, UK.<br /><searchLink fieldCode="AU" term="%22Ducray+SP%22">Ducray SP</searchLink>; Division of Cellular and Molecular Pathology, Department of Pathology, University of Cambridge, Cambridge, CB20QQ, UK.<br /><searchLink fieldCode="AU" term="%22Burke+GAA%22">Burke GAA</searchLink>; CRUK Clinical Trials Unit, University of Birmingham, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Goodman+A%22">Goodman A</searchLink>; Newcastle Genetics Laboratory, Newcastle Upon Tyne Hospitals NHS Trust, Newcastle Upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Woodward+ER%22">Woodward ER</searchLink>; Department of Paediatric Oncology, Royal Manchester Children's Hospital, Division of Cancer Sciences, University of Manchester & Manchester Centre for Genomic Medicine, Manchester, M13 9WL, UK.<br /><searchLink fieldCode="AU" term="%22Cheesman+E%22">Cheesman E</searchLink>; Department of Paediatric Oncology, Royal Manchester Children's Hospital, Division of Cancer Sciences, University of Manchester & Manchester Centre for Genomic Medicine, Manchester, M13 9WL, UK.<br /><searchLink fieldCode="AU" term="%22Penn+A%22">Penn A</searchLink>; Department of Paediatric Oncology, Royal Manchester Children's Hospital, Division of Cancer Sciences, University of Manchester & Manchester Centre for Genomic Medicine, Manchester, M13 9WL, UK.<br /><searchLink fieldCode="AU" term="%22Mondal+T%22">Mondal T</searchLink>; Department of Laboratory Medicine, Institute of Biomedicine, University of Gothenburg, Sweden; Department of Clinical Chemistry, Sahlgrenska University Hospital, Gothenburg, Region Västra Götaland, Sweden.<br /><searchLink fieldCode="AU" term="%22Turner+SD%22">Turner SD</searchLink>; Division of Cellular and Molecular Pathology, Department of Pathology, University of Cambridge, Cambridge, CB20QQ, UK; European Research Initiative for ALK Related Malignancies (ERIA), UK; Faculty of Medicine, Masaryk University, Brno, Czech Republic. Electronic address: sdt36@cam.ac.uk.<br /><searchLink fieldCode="AU" term="%22Pucci+P%22">Pucci P</searchLink>; Division of Cellular and Molecular Pathology, Department of Pathology, University of Cambridge, Cambridge, CB20QQ, UK. Electronic address: pp504@cam.ac.uk.
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  Data: <searchLink fieldCode="JN" term="%227600053%22">Cancer letters</searchLink> [Cancer Lett] 2026 Sep 28; Vol. 656, pp. 218624. <i>Date of Electronic Publication: </i>2026 May 29.
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