Novel gastroprotective role of Alogliptin: Modulating the GDNF/PI3K/Akt/GSK3β, SDF-1/CXCR4, and CREB/COX-2/PGE2 signalling pathways to ameliorate diclofenac-induced peptic ulcer in rats.
Saved in:
| Title: | Novel gastroprotective role of Alogliptin: Modulating the GDNF/PI3K/Akt/GSK3β, SDF-1/CXCR4, and CREB/COX-2/PGE2 signalling pathways to ameliorate diclofenac-induced peptic ulcer in rats. |
|---|---|
| Authors: | Ghoneim ME; Department of Pharmacology and Toxicology, Faculty of Pharmacy, University of Sadat City (USC), Sadat City, 32897, Egypt. Electronic address: mai.ghoneim@fop.usc.edu.eg., Noureldin MH; Department of Biochemistry, Clinical and Biological Sciences Division, College of Pharmacy, Arab Academy for Science, Technology and Maritime Transport, P.O. Box 1029, Alexandria, Egypt. Electronic address: Mohamed.noureldin@aast.edu., El Sayed I; Department of Pharmacy, Faculty of Pharmacy, Nursing and Medical Sciences, Riyadh Elm University, Riyadh, Saudi Arabia. Electronic address: Ibrahim.hassan@riyadh.edu.sa., El Banna YY; Department of Pharmacology and Toxicology, Clinical and Biological Sciences Division, College of Pharmacy, Arab Academy for Science, Technology and Maritime Transport, P.O. Box 1029, Alexandria, Egypt. Electronic address: yousrayelbanna@aast.edu., El Sayed NF; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Ahram Canadian University, Giza, Egypt. Electronic address: Nermein.fawzy@acu.edu.eg. |
| Source: | European journal of pharmacology [Eur J Pharmacol] 2026 Jul 10; Vol. 1029, pp. 179066. Date of Electronic Publication: 2026 May 30. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0712 (Electronic) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur J Pharmacol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
|---|---|
| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42217721 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: Novel gastroprotective role of Alogliptin: Modulating the GDNF/PI3K/Akt/GSK3β, SDF-1/CXCR4, and CREB/COX-2/PGE2 signalling pathways to ameliorate diclofenac-induced peptic ulcer in rats. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Ghoneim+ME%22">Ghoneim ME</searchLink>; Department of Pharmacology and Toxicology, Faculty of Pharmacy, University of Sadat City (USC), Sadat City, 32897, Egypt. Electronic address: mai.ghoneim@fop.usc.edu.eg.<br /><searchLink fieldCode="AU" term="%22Noureldin+MH%22">Noureldin MH</searchLink>; Department of Biochemistry, Clinical and Biological Sciences Division, College of Pharmacy, Arab Academy for Science, Technology and Maritime Transport, P.O. Box 1029, Alexandria, Egypt. Electronic address: Mohamed.noureldin@aast.edu.<br /><searchLink fieldCode="AU" term="%22El+Sayed+I%22">El Sayed I</searchLink>; Department of Pharmacy, Faculty of Pharmacy, Nursing and Medical Sciences, Riyadh Elm University, Riyadh, Saudi Arabia. Electronic address: Ibrahim.hassan@riyadh.edu.sa.<br /><searchLink fieldCode="AU" term="%22El+Banna+YY%22">El Banna YY</searchLink>; Department of Pharmacology and Toxicology, Clinical and Biological Sciences Division, College of Pharmacy, Arab Academy for Science, Technology and Maritime Transport, P.O. Box 1029, Alexandria, Egypt. Electronic address: yousrayelbanna@aast.edu.<br /><searchLink fieldCode="AU" term="%22El+Sayed+NF%22">El Sayed NF</searchLink>; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Ahram Canadian University, Giza, Egypt. Electronic address: Nermein.fawzy@acu.edu.eg. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%221254354%22">European journal of pharmacology</searchLink> [Eur J Pharmacol] 2026 Jul 10; Vol. 1029, pp. 179066. <i>Date of Electronic Publication: </i>2026 May 30. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science%22">Elsevier Science </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>1254354 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1879-0712 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200142999%22">00142999 </searchLink><i>NLM ISO Abbreviation: </i>Eur J Pharmacol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42217721 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.ejphar.2026.179066 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 179066 Titles: – TitleFull: Novel gastroprotective role of Alogliptin: Modulating the GDNF/PI3K/Akt/GSK3β, SDF-1/CXCR4, and CREB/COX-2/PGE2 signalling pathways to ameliorate diclofenac-induced peptic ulcer in rats. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Ghoneim ME – PersonEntity: Name: NameFull: Noureldin MH – PersonEntity: Name: NameFull: El Sayed I – PersonEntity: Name: NameFull: El Banna YY – PersonEntity: Name: NameFull: El Sayed NF IsPartOfRelationships: – BibEntity: Dates: – D: 10 M: 07 Text: 2026 Jul 10 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1879-0712 Numbering: – Type: volume Value: 1029 Titles: – TitleFull: European journal of pharmacology Type: main |
| ResultId | 1 |
