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Benefits of 12-week self-paced training combined with melatonin supplementation on oxidative stress, inflammation, hyperlipidemia, and body composition in multiple sclerosis patients: A randomized controlled trial.

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Title: Benefits of 12-week self-paced training combined with melatonin supplementation on oxidative stress, inflammation, hyperlipidemia, and body composition in multiple sclerosis patients: A randomized controlled trial.
Authors: Jallouli S; Research laboratory: Evaluation and Management of Musculoskeletal System Pathologies, LR20ES09, Faculty of Medicine, University of Sfax, Sfax, Tunisia; Research Laboratory: Education, Motricity, Sport and Health (EM2S), LR19JS01, High Institute of Sport and Physical Education of Sfax, University of Sfax, Sfax, Tunisia. Electronic address: sonda.jallouli@isseps.usf.tn., Jallouli D; Research Laboratory, Molecular Bases of Human Pathology, LR19ES13, Faculty of Medicine, University of Sfax, Sfax, Tunisia; Laboratory of Biochemistry, Habib Bourguiba University Hospital, University of Sfax, Sfax, Tunisia., Kallel C; Hematology Laboratory, Habib Bourguiba University Hospital, Sfax, Tunisia., Sakka S; Laboratory of Neurogenetics, Parkinson's Disease and Cerebrovascular Disease, LR12SP19, Habib Bourguiba University Hospital, University of Sfax, Sfax, Tunisia., Damak M; Laboratory of Neurogenetics, Parkinson's Disease and Cerebrovascular Disease, LR12SP19, Habib Bourguiba University Hospital, University of Sfax, Sfax, Tunisia., Jaafar B; Research Laboratory: Education, Motricity, Sport and Health (EM2S), LR19JS01, High Institute of Sport and Physical Education of Sfax, University of Sfax, Sfax, Tunisia., Mhiri C; Laboratory of Neurogenetics, Parkinson's Disease and Cerebrovascular Disease, LR12SP19, Habib Bourguiba University Hospital, University of Sfax, Sfax, Tunisia., de Marco G; LINP2, UFR STAPS, University of Paris Nanterre, Nanterre, France., Driss T; LINP2, UFR STAPS, University of Paris Nanterre, Nanterre, France., Ayadi F; Research Laboratory, Molecular Bases of Human Pathology, LR19ES13, Faculty of Medicine, University of Sfax, Sfax, Tunisia; Laboratory of Biochemistry, Habib Bourguiba University Hospital, University of Sfax, Sfax, Tunisia., Hammouda O; Research Laboratory: Education, Motricity, Sport and Health (EM2S), LR19JS01, High Institute of Sport and Physical Education of Sfax, University of Sfax, Sfax, Tunisia; Research Laboratory, Molecular Bases of Human Pathology, LR19ES13, Faculty of Medicine, University of Sfax, Sfax, Tunisia; LINP2, UFR STAPS, University of Paris Nanterre, Nanterre, France. Electronic address: omar.hammouda@parisnanterre.fr.
Source: Brain research bulletin [Brain Res Bull] 2026 Sep; Vol. 243, pp. 111968. Date of Electronic Publication: 2026 May 29.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 7605818 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2747 (Electronic) Linking ISSN: 03619230 NLM ISO Abbreviation: Brain Res Bull Subsets: MEDLINE
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  Data: Benefits of 12-week self-paced training combined with melatonin supplementation on oxidative stress, inflammation, hyperlipidemia, and body composition in multiple sclerosis patients: A randomized controlled trial.
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  Data: <searchLink fieldCode="AU" term="%22Jallouli+S%22">Jallouli S</searchLink>; Research laboratory: Evaluation and Management of Musculoskeletal System Pathologies, LR20ES09, Faculty of Medicine, University of Sfax, Sfax, Tunisia; Research Laboratory: Education, Motricity, Sport and Health (EM2S), LR19JS01, High Institute of Sport and Physical Education of Sfax, University of Sfax, Sfax, Tunisia. Electronic address: sonda.jallouli@isseps.usf.tn.<br /><searchLink fieldCode="AU" term="%22Jallouli+D%22">Jallouli D</searchLink>; Research Laboratory, Molecular Bases of Human Pathology, LR19ES13, Faculty of Medicine, University of Sfax, Sfax, Tunisia; Laboratory of Biochemistry, Habib Bourguiba University Hospital, University of Sfax, Sfax, Tunisia.<br /><searchLink fieldCode="AU" term="%22Kallel+C%22">Kallel C</searchLink>; Hematology Laboratory, Habib Bourguiba University Hospital, Sfax, Tunisia.<br /><searchLink fieldCode="AU" term="%22Sakka+S%22">Sakka S</searchLink>; Laboratory of Neurogenetics, Parkinson's Disease and Cerebrovascular Disease, LR12SP19, Habib Bourguiba University Hospital, University of Sfax, Sfax, Tunisia.<br /><searchLink fieldCode="AU" term="%22Damak+M%22">Damak M</searchLink>; Laboratory of Neurogenetics, Parkinson's Disease and Cerebrovascular Disease, LR12SP19, Habib Bourguiba University Hospital, University of Sfax, Sfax, Tunisia.<br /><searchLink fieldCode="AU" term="%22Jaafar+B%22">Jaafar B</searchLink>; Research Laboratory: Education, Motricity, Sport and Health (EM2S), LR19JS01, High Institute of Sport and Physical Education of Sfax, University of Sfax, Sfax, Tunisia.<br /><searchLink fieldCode="AU" term="%22Mhiri+C%22">Mhiri C</searchLink>; Laboratory of Neurogenetics, Parkinson's Disease and Cerebrovascular Disease, LR12SP19, Habib Bourguiba University Hospital, University of Sfax, Sfax, Tunisia.<br /><searchLink fieldCode="AU" term="%22de+Marco+G%22">de Marco G</searchLink>; LINP2, UFR STAPS, University of Paris Nanterre, Nanterre, France.<br /><searchLink fieldCode="AU" term="%22Driss+T%22">Driss T</searchLink>; LINP2, UFR STAPS, University of Paris Nanterre, Nanterre, France.<br /><searchLink fieldCode="AU" term="%22Ayadi+F%22">Ayadi F</searchLink>; Research Laboratory, Molecular Bases of Human Pathology, LR19ES13, Faculty of Medicine, University of Sfax, Sfax, Tunisia; Laboratory of Biochemistry, Habib Bourguiba University Hospital, University of Sfax, Sfax, Tunisia.<br /><searchLink fieldCode="AU" term="%22Hammouda+O%22">Hammouda O</searchLink>; Research Laboratory: Education, Motricity, Sport and Health (EM2S), LR19JS01, High Institute of Sport and Physical Education of Sfax, University of Sfax, Sfax, Tunisia; Research Laboratory, Molecular Bases of Human Pathology, LR19ES13, Faculty of Medicine, University of Sfax, Sfax, Tunisia; LINP2, UFR STAPS, University of Paris Nanterre, Nanterre, France. Electronic address: omar.hammouda@parisnanterre.fr.
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  Data: <searchLink fieldCode="JN" term="%227605818%22">Brain research bulletin</searchLink> [Brain Res Bull] 2026 Sep; Vol. 243, pp. 111968. <i>Date of Electronic Publication: </i>2026 May 29.
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              Text: 2026 Sep
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