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Novel Gemini surfactant-polyglutamic acid composite system enhances DNA delivery via a "Dual-Engine" uptake strategy.

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Title: Novel Gemini surfactant-polyglutamic acid composite system enhances DNA delivery via a "Dual-Engine" uptake strategy.
Authors: Chen Y; College of Pharmacy, Chongqing Medical University, Yixueyuan Road, Yuzhong District, Chongqing 400016, PR China., Qian P; College of Pharmacy, Chongqing Medical University, Yixueyuan Road, Yuzhong District, Chongqing 400016, PR China., Lv J; College of Pharmacy, Chongqing Medical University, Yixueyuan Road, Yuzhong District, Chongqing 400016, PR China., Gan Z; College of Pharmacy, Chongqing Medical University, Yixueyuan Road, Yuzhong District, Chongqing 400016, PR China., Jiang D; College of Pharmacy, Chongqing Medical University, Yixueyuan Road, Yuzhong District, Chongqing 400016, PR China., Xiao H; School of Pharmacy, Zunyi Medical University, Zunyi 563000, PR China., Li R; School of Pharmacy, Zunyi Medical University, Zunyi 563000, PR China., Zhang Q; College of Pharmacy, Chongqing Medical University, Yixueyuan Road, Yuzhong District, Chongqing 400016, PR China., Chen S; School of Pharmacy, Zunyi Medical University, Zunyi 563000, PR China., Ping Y; School of Pharmacy, Zunyi Medical University, Zunyi 563000, PR China; College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, PR China., Chen H; College of Pharmacy, Chongqing Medical University, Yixueyuan Road, Yuzhong District, Chongqing 400016, PR China. Electronic address: chenhuali@cqmu.edu.cn.
Source: International journal of pharmaceutics [Int J Pharm] 2026 Jul 10; Vol. 700, pp. 127037. Date of Electronic Publication: 2026 May 29.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3476 (Electronic) Linking ISSN: 03785173 NLM ISO Abbreviation: Int J Pharm Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Novel Gemini surfactant-polyglutamic acid composite system enhances DNA delivery via a "Dual-Engine" uptake strategy.
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  Data: <searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; College of Pharmacy, Chongqing Medical University, Yixueyuan Road, Yuzhong District, Chongqing 400016, PR China.<br /><searchLink fieldCode="AU" term="%22Qian+P%22">Qian P</searchLink>; College of Pharmacy, Chongqing Medical University, Yixueyuan Road, Yuzhong District, Chongqing 400016, PR China.<br /><searchLink fieldCode="AU" term="%22Lv+J%22">Lv J</searchLink>; College of Pharmacy, Chongqing Medical University, Yixueyuan Road, Yuzhong District, Chongqing 400016, PR China.<br /><searchLink fieldCode="AU" term="%22Gan+Z%22">Gan Z</searchLink>; College of Pharmacy, Chongqing Medical University, Yixueyuan Road, Yuzhong District, Chongqing 400016, PR China.<br /><searchLink fieldCode="AU" term="%22Jiang+D%22">Jiang D</searchLink>; College of Pharmacy, Chongqing Medical University, Yixueyuan Road, Yuzhong District, Chongqing 400016, PR China.<br /><searchLink fieldCode="AU" term="%22Xiao+H%22">Xiao H</searchLink>; School of Pharmacy, Zunyi Medical University, Zunyi 563000, PR China.<br /><searchLink fieldCode="AU" term="%22Li+R%22">Li R</searchLink>; School of Pharmacy, Zunyi Medical University, Zunyi 563000, PR China.<br /><searchLink fieldCode="AU" term="%22Zhang+Q%22">Zhang Q</searchLink>; College of Pharmacy, Chongqing Medical University, Yixueyuan Road, Yuzhong District, Chongqing 400016, PR China.<br /><searchLink fieldCode="AU" term="%22Chen+S%22">Chen S</searchLink>; School of Pharmacy, Zunyi Medical University, Zunyi 563000, PR China.<br /><searchLink fieldCode="AU" term="%22Ping+Y%22">Ping Y</searchLink>; School of Pharmacy, Zunyi Medical University, Zunyi 563000, PR China; College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, PR China.<br /><searchLink fieldCode="AU" term="%22Chen+H%22">Chen H</searchLink>; College of Pharmacy, Chongqing Medical University, Yixueyuan Road, Yuzhong District, Chongqing 400016, PR China. Electronic address: chenhuali@cqmu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%227804127%22">International journal of pharmaceutics</searchLink> [Int J Pharm] 2026 Jul 10; Vol. 700, pp. 127037. <i>Date of Electronic Publication: </i>2026 May 29.
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              Text: 2026 Jul 10
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