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Accuracy of Index Lymph Node Pathology in Predicting Overall Response to Neoadjuvant Immunotherapy for Clinical Stage III Melanoma: Results From the Prospective NeoACTIVATE Arm C (NCT03554083) Substudy.

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Title: Accuracy of Index Lymph Node Pathology in Predicting Overall Response to Neoadjuvant Immunotherapy for Clinical Stage III Melanoma: Results From the Prospective NeoACTIVATE Arm C (NCT03554083) Substudy.
Authors: Hieken TJ; Division of Breast and Melanoma Surgical Oncology, Department of Surgery, Mayo Clinic, Rochester, MN, USA. hieken.tina@mayo.edu.; Mayo Clinic Comprehensive Cancer Center, Rochester, MN, USA. hieken.tina@mayo.edu., Flotte TJ; Mayo Clinic Comprehensive Cancer Center, Rochester, MN, USA.; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA., Zahrieh D; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA., Johnson JE; Division of Breast and Melanoma Surgical Oncology, Department of Surgery, Mayo Clinic, Rochester, MN, USA., Piltin MA; Division of Breast and Melanoma Surgical Oncology, Department of Surgery, Mayo Clinic, Rochester, MN, USA., Tasche KK; Department of Otolaryngology, Mayo Clinic, Rochester, MN, USA., Nelson GD; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA., Strand CA; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA., Jakub JW; Department of Surgery, Mayo Clinic, Jacksonville, FL, USA., Pirgousis P; Department of Otorhinolaryngology, Mayo Clinic, Jacksonville, FL, USA., Khariwala SS; Department of Otolaryngology, University of Minnesota, Minneapolis, MN, USA., Tuttle T; Division of Surgical Oncology, Department of Surgery, University of Minnesota, Minneapolis, MN, USA., Block MS; Mayo Clinic Comprehensive Cancer Center, Rochester, MN, USA.; Department of Oncology, Mayo Clinic, Rochester, MN, USA.
Source: Annals of surgical oncology [Ann Surg Oncol] 2026 Aug; Vol. 33 (8), pp. 7471-7476. Date of Electronic Publication: 2026 May 30.
Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study
Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 9420840 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1534-4681 (Electronic) Linking ISSN: 10689265 NLM ISO Abbreviation: Ann Surg Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Accuracy of Index Lymph Node Pathology in Predicting Overall Response to Neoadjuvant Immunotherapy for Clinical Stage III Melanoma: Results From the Prospective NeoACTIVATE Arm C (NCT03554083) Substudy.
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  Data: <searchLink fieldCode="AU" term="%22Hieken+TJ%22">Hieken TJ</searchLink>; Division of Breast and Melanoma Surgical Oncology, Department of Surgery, Mayo Clinic, Rochester, MN, USA. hieken.tina@mayo.edu.; Mayo Clinic Comprehensive Cancer Center, Rochester, MN, USA. hieken.tina@mayo.edu.<br /><searchLink fieldCode="AU" term="%22Flotte+TJ%22">Flotte TJ</searchLink>; Mayo Clinic Comprehensive Cancer Center, Rochester, MN, USA.; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Zahrieh+D%22">Zahrieh D</searchLink>; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Johnson+JE%22">Johnson JE</searchLink>; Division of Breast and Melanoma Surgical Oncology, Department of Surgery, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Piltin+MA%22">Piltin MA</searchLink>; Division of Breast and Melanoma Surgical Oncology, Department of Surgery, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Tasche+KK%22">Tasche KK</searchLink>; Department of Otolaryngology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Nelson+GD%22">Nelson GD</searchLink>; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Strand+CA%22">Strand CA</searchLink>; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Jakub+JW%22">Jakub JW</searchLink>; Department of Surgery, Mayo Clinic, Jacksonville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Pirgousis+P%22">Pirgousis P</searchLink>; Department of Otorhinolaryngology, Mayo Clinic, Jacksonville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Khariwala+SS%22">Khariwala SS</searchLink>; Department of Otolaryngology, University of Minnesota, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Tuttle+T%22">Tuttle T</searchLink>; Division of Surgical Oncology, Department of Surgery, University of Minnesota, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Block+MS%22">Block MS</searchLink>; Mayo Clinic Comprehensive Cancer Center, Rochester, MN, USA.; Department of Oncology, Mayo Clinic, Rochester, MN, USA.
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  Data: <searchLink fieldCode="JN" term="%229420840%22">Annals of surgical oncology</searchLink> [Ann Surg Oncol] 2026 Aug; Vol. 33 (8), pp. 7471-7476. <i>Date of Electronic Publication: </i>2026 May 30.
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