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A randomized phase III trial of anthracyclines followed by taxane versus taxane plus carboplatin as (neo)adjuvant therapy in patients with triple-negative breast cancer: KCSG BR 15-1 PEARLY trial.

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Title: A randomized phase III trial of anthracyclines followed by taxane versus taxane plus carboplatin as (neo)adjuvant therapy in patients with triple-negative breast cancer: KCSG BR 15-1 PEARLY trial.
Authors: Kim GM; Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Republic of Korea., Jung KH; Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea., Jeung HC; Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea., Lee J; Division of Medical Oncology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea., Lee KS; Department of Internal Medicine, Center for Breast Cancer, Research Institute and Hospital, National Cancer Center, Goyang, Republic of Korea., Im SA; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea., Kang SY; Department of Hematology-Oncology, Ajou University School of Medicine, Suwon, Republic of Korea., Kim SH; Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Republic of Korea., Kim HJ; Division of Oncology and Hematology, Department of Internal Medicine, Soonchunhyang University Cheonan Hospital, Cheonan, Republic of Korea., Park KH; Division of Medical Oncology, Department of Internal Medicine, Korea University Anam Hospital, Seoul, Republic of Korea., Chae YS; Department of Oncology/Hematology, Kyungpook National University Chilgok Hospital, School of Medicine, Kyungpook National University, Daegu, Republic of Korea., Koh SJ; Division of Hematology and Oncology, Department of Internal Medicine, Ulsan University Hospital, Ulsan University College of Medicine, Ulsan, Republic of Korea., Cho EK; Division of Medical Oncology, Department of Internal Medicine, Gachon University Gil Medical Center, Incheon, Republic of Korea., Park KU; Department of Internal Medicine, Keimyung University Dongsan Hospital, Daegu, Republic of Korea., Lee SS; Department of Hematology-Oncology, Inje University Haeundae Paik Hospital, Inje University College of Medicine, Busan, Republic of Korea., Kim JY; Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea., Choi IS; Department of Internal Medicine, Seoul Municipal Boramae Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea., Baek SK; Department of Internal Medicine, Kyung Hee University Hospital, Seoul, Republic of Korea., Moon YW; Hematology and Oncology, Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Republic of Korea., Kim SG; Hematology and Oncology, Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Republic of Korea., Lim ST; Department of Hematology and Medical Oncology, Wonju Severance Christian Hospital, Wonju, Republic of Korea., Lee KH; Internal Medicine Department, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju, Republic of Korea., Kim HJ; Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Republic of Korea., Kim MH; Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Republic of Korea., Kim KH; Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Republic of Korea., Kim SI; Department of Surgery, Yonsei University College of Medicine, Seoul, Republic of Korea., Park S; Department of Surgery, Yonsei University College of Medicine, Seoul, Republic of Korea., Park HS; Department of Surgery, Yonsei University College of Medicine, Seoul, Republic of Korea., Kim JY; Department of Surgery, Yonsei University College of Medicine, Seoul, Republic of Korea., Kim YB; Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea., Kim SB; Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea., Ahn JH; Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea., Jeong JH; Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea., Kim JH; Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea., Jeong J; Department of Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea., Park WC; Division of Medical Oncology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea., Sim SH; Department of Internal Medicine, Center for Breast Cancer, Research Institute and Hospital, National Cancer Center, Goyang, Republic of Korea., Lee K; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea., Nam CM; Department of Public Health, Graduate School, Yonsei University, Seoul, Republic of Korea., Park S; Department of Research Support, Songdang Institute for Cancer Research, Yonsei, University College of Medicine, Seoul, Republic of Korea., Paik S; Department of Medical Oncology, Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Republic of Korea., Sohn J; Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Republic of Korea. Electronic address: oncosohn@yuhs.ac.
Corporate Authors: Korean Cancer Study Group (KCSG)
Source: Annals of oncology : official journal of the European Society for Medical Oncology [Ann Oncol] 2026 May 30. Date of Electronic Publication: 2026 May 30.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 9007735 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1569-8041 (Electronic) Linking ISSN: 09237534 NLM ISO Abbreviation: Ann Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A randomized phase III trial of anthracyclines followed by taxane versus taxane plus carboplatin as (neo)adjuvant therapy in patients with triple-negative breast cancer: KCSG BR 15-1 PEARLY trial.
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  Data: <searchLink fieldCode="AU" term="%22Kim+GM%22">Kim GM</searchLink>; Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jung+KH%22">Jung KH</searchLink>; Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jeung+HC%22">Jeung HC</searchLink>; Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+J%22">Lee J</searchLink>; Division of Medical Oncology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+KS%22">Lee KS</searchLink>; Department of Internal Medicine, Center for Breast Cancer, Research Institute and Hospital, National Cancer Center, Goyang, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Im+SA%22">Im SA</searchLink>; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kang+SY%22">Kang SY</searchLink>; Department of Hematology-Oncology, Ajou University School of Medicine, Suwon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+SH%22">Kim SH</searchLink>; Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+HJ%22">Kim HJ</searchLink>; Division of Oncology and Hematology, Department of Internal Medicine, Soonchunhyang University Cheonan Hospital, Cheonan, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+KH%22">Park KH</searchLink>; Division of Medical Oncology, Department of Internal Medicine, Korea University Anam Hospital, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Chae+YS%22">Chae YS</searchLink>; Department of Oncology/Hematology, Kyungpook National University Chilgok Hospital, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Koh+SJ%22">Koh SJ</searchLink>; Division of Hematology and Oncology, Department of Internal Medicine, Ulsan University Hospital, Ulsan University College of Medicine, Ulsan, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Cho+EK%22">Cho EK</searchLink>; Division of Medical Oncology, Department of Internal Medicine, Gachon University Gil Medical Center, Incheon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+KU%22">Park KU</searchLink>; Department of Internal Medicine, Keimyung University Dongsan Hospital, Daegu, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+SS%22">Lee SS</searchLink>; Department of Hematology-Oncology, Inje University Haeundae Paik Hospital, Inje University College of Medicine, Busan, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+JY%22">Kim JY</searchLink>; Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Choi+IS%22">Choi IS</searchLink>; Department of Internal Medicine, Seoul Municipal Boramae Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Baek+SK%22">Baek SK</searchLink>; Department of Internal Medicine, Kyung Hee University Hospital, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Moon+YW%22">Moon YW</searchLink>; Hematology and Oncology, Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+SG%22">Kim SG</searchLink>; Hematology and Oncology, Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lim+ST%22">Lim ST</searchLink>; Department of Hematology and Medical Oncology, Wonju Severance Christian Hospital, Wonju, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+KH%22">Lee KH</searchLink>; Internal Medicine Department, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+HJ%22">Kim HJ</searchLink>; Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+MH%22">Kim MH</searchLink>; Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+KH%22">Kim KH</searchLink>; Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+SI%22">Kim SI</searchLink>; Department of Surgery, Yonsei University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+S%22">Park S</searchLink>; Department of Surgery, Yonsei University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+HS%22">Park HS</searchLink>; Department of Surgery, Yonsei University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+JY%22">Kim JY</searchLink>; Department of Surgery, Yonsei University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+YB%22">Kim YB</searchLink>; Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+SB%22">Kim SB</searchLink>; Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Ahn+JH%22">Ahn JH</searchLink>; Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jeong+JH%22">Jeong JH</searchLink>; Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+JH%22">Kim JH</searchLink>; Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jeong+J%22">Jeong J</searchLink>; Department of Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+WC%22">Park WC</searchLink>; Division of Medical Oncology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Sim+SH%22">Sim SH</searchLink>; Department of Internal Medicine, Center for Breast Cancer, Research Institute and Hospital, National Cancer Center, Goyang, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+K%22">Lee K</searchLink>; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Nam+CM%22">Nam CM</searchLink>; Department of Public Health, Graduate School, Yonsei University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+S%22">Park S</searchLink>; Department of Research Support, Songdang Institute for Cancer Research, Yonsei, University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Paik+S%22">Paik S</searchLink>; Department of Medical Oncology, Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Sohn+J%22">Sohn J</searchLink>; Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Republic of Korea. Electronic address: oncosohn@yuhs.ac.
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