A pragmatic randomized trial to evaluate the vaccine effectiveness of bivalent RSV prefusion F vaccine for preventing RSV hospitalizations in adults (DAN-RSV): Trial design update.
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| Title: | A pragmatic randomized trial to evaluate the vaccine effectiveness of bivalent RSV prefusion F vaccine for preventing RSV hospitalizations in adults (DAN-RSV): Trial design update. |
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| Authors: | Lassen MCH; Department of Cardiology, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark; Center for Translational Cardiology and Pragmatic Randomized Trials, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Christensen SH; Department of Cardiology, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark; Center for Translational Cardiology and Pragmatic Randomized Trials, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Johansen ND; Department of Cardiology, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark; Center for Translational Cardiology and Pragmatic Randomized Trials, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Yafasov M; Department of Cardiology, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark; Center for Translational Cardiology and Pragmatic Randomized Trials, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Pareek M; Department of Cardiology, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark; Center for Translational Cardiology and Pragmatic Randomized Trials, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Rudolph AE; Pfizer, New York, NY., Tenreiro-Sánchez CR; Genetics, Vaccines and Infectious Diseases Research Group (GENVIP), Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Santiago de Compostela, Galicia, Spain; WHO Collaborating Centre for Vaccine Safety, Santiago de Compostela, Galicia, Spain; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain; Translational Pediatrics and Infectious Diseases, Hospital Clínico Universitario de Santiago (SERGAS) and University of Santiago de Compostela (USC), Santiago de Compostela, Galicia, Spain., Skaarup KG; Department of Cardiology, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark; Center for Translational Cardiology and Pragmatic Randomized Trials, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Modin D; Department of Cardiology, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark; Center for Translational Cardiology and Pragmatic Randomized Trials, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Claggett BL; Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA., Larsen CS; Department of Clinical Medicine-Department of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark., Larsen L; Research Unit for Infectious Diseases, Odense University Hospital, Odense, Denmark., Wiese L; Department of Infectious Diseases, Zealand University Hospital, Roskilde, Denmark., Dalager-Pedersen M; Department of Infectious Diseases, Aalborg University Hospital, Aalborg, Denmark; Department of Clinical Medicine, Aalborg University Hospital, Aalborg, Denmark., Lindholm MG; Department of Cardiology, Zealand University Hospital Roskilde, Roskilde, Denmark., Køber L; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Cardiology, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark., Solomon SD; Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA., Jensen JUS; Department of Cardiology, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark; Respiratory Medicine Section, Department of Medicine, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark., Martel CJ; Epidemiological Infectious Disease Preparedness, Statens Serum Institute, Copenhagen, Denmark., Aliabadi N; Pfizer, New York, NY., Schwarz C; Pfizer, New York, NY., Skovdal M; Pfizer, New York, NY., Zhang P; Pfizer, New York, NY., López-Gómez V; Pfizer, New York, NY., Welsh S; Pfizer, New York, NY., Gessner BD; Pfizer, New York, NY., Martinón-Torres F; Genetics, Vaccines and Infectious Diseases Research Group (GENVIP), Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Santiago de Compostela, Galicia, Spain; WHO Collaborating Centre for Vaccine Safety, Santiago de Compostela, Galicia, Spain; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain; Translational Pediatrics and Infectious Diseases, Hospital Clínico Universitario de Santiago (SERGAS) and University of Santiago de Compostela (USC), Santiago de Compostela, Galicia, Spain., Begier E; Pfizer, New York, NY., Biering-Sørensen T; Department of Cardiology, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark; Center for Translational Cardiology and Pragmatic Randomized Trials, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Steno Diabetes Center Copenhagen, Copenhagen, Denmark. Electronic address: tor.biering@gmail.com. |
| Source: | American heart journal [Am Heart J] 2026 Oct; Vol. 300, pp. 107497. Date of Electronic Publication: 2026 Jun 01. |
| Publication Type: | Journal Article; Pragmatic Clinical Trial; Randomized Controlled Trial |
| Journal Info: | Publisher: Mosby Country of Publication: United States NLM ID: 0370465 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6744 (Electronic) Linking ISSN: 00028703 NLM ISO Abbreviation: Am Heart J Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42219049 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: A pragmatic randomized trial to evaluate the vaccine effectiveness of bivalent RSV prefusion F vaccine for preventing RSV hospitalizations in adults (DAN-RSV): Trial design update. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Lassen+MCH%22">Lassen MCH</searchLink>; Department of Cardiology, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark; Center for Translational Cardiology and Pragmatic Randomized Trials, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Christensen+SH%22">Christensen SH</searchLink>; Department of Cardiology, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark; Center for Translational Cardiology and Pragmatic Randomized Trials, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Johansen+ND%22">Johansen ND</searchLink>; Department of Cardiology, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark; Center for Translational Cardiology and Pragmatic Randomized Trials, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Yafasov+M%22">Yafasov M</searchLink>; Department of Cardiology, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark; Center for Translational Cardiology and Pragmatic Randomized Trials, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Pareek+M%22">Pareek M</searchLink>; Department of Cardiology, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark; Center for Translational Cardiology and Pragmatic Randomized Trials, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Rudolph+AE%22">Rudolph AE</searchLink>; Pfizer, New York, NY.<br /><searchLink fieldCode="AU" term="%22Tenreiro-Sánchez+CR%22">Tenreiro-Sánchez CR</searchLink>; Genetics, Vaccines and Infectious Diseases Research Group (GENVIP), Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Santiago de Compostela, Galicia, Spain; WHO Collaborating Centre for Vaccine Safety, Santiago de Compostela, Galicia, Spain; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain; Translational Pediatrics and Infectious Diseases, Hospital Clínico Universitario de Santiago (SERGAS) and University of Santiago de Compostela (USC), Santiago de Compostela, Galicia, Spain.<br /><searchLink fieldCode="AU" term="%22Skaarup+KG%22">Skaarup KG</searchLink>; Department of Cardiology, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark; Center for Translational Cardiology and Pragmatic Randomized Trials, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Modin+D%22">Modin D</searchLink>; Department of Cardiology, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark; Center for Translational Cardiology and Pragmatic Randomized Trials, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Claggett+BL%22">Claggett BL</searchLink>; Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Larsen+CS%22">Larsen CS</searchLink>; Department of Clinical Medicine-Department of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Larsen+L%22">Larsen L</searchLink>; Research Unit for Infectious Diseases, Odense University Hospital, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Wiese+L%22">Wiese L</searchLink>; Department of Infectious Diseases, Zealand University Hospital, Roskilde, Denmark.<br /><searchLink fieldCode="AU" term="%22Dalager-Pedersen+M%22">Dalager-Pedersen M</searchLink>; Department of Infectious Diseases, Aalborg University Hospital, Aalborg, Denmark; Department of Clinical Medicine, Aalborg University Hospital, Aalborg, Denmark.<br /><searchLink fieldCode="AU" term="%22Lindholm+MG%22">Lindholm MG</searchLink>; Department of Cardiology, Zealand University Hospital Roskilde, Roskilde, Denmark.<br /><searchLink fieldCode="AU" term="%22Køber+L%22">Køber L</searchLink>; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Cardiology, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Solomon+SD%22">Solomon SD</searchLink>; Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Jensen+JUS%22">Jensen JUS</searchLink>; Department of Cardiology, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark; Respiratory Medicine Section, Department of Medicine, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Martel+CJ%22">Martel CJ</searchLink>; Epidemiological Infectious Disease Preparedness, Statens Serum Institute, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Aliabadi+N%22">Aliabadi N</searchLink>; Pfizer, New York, NY.<br /><searchLink fieldCode="AU" term="%22Schwarz+C%22">Schwarz C</searchLink>; Pfizer, New York, NY.<br /><searchLink fieldCode="AU" term="%22Skovdal+M%22">Skovdal M</searchLink>; Pfizer, New York, NY.<br /><searchLink fieldCode="AU" term="%22Zhang+P%22">Zhang P</searchLink>; Pfizer, New York, NY.<br /><searchLink fieldCode="AU" term="%22López-Gómez+V%22">López-Gómez V</searchLink>; Pfizer, New York, NY.<br /><searchLink fieldCode="AU" term="%22Welsh+S%22">Welsh S</searchLink>; Pfizer, New York, NY.<br /><searchLink fieldCode="AU" term="%22Gessner+BD%22">Gessner BD</searchLink>; Pfizer, New York, NY.<br /><searchLink fieldCode="AU" term="%22Martinón-Torres+F%22">Martinón-Torres F</searchLink>; Genetics, Vaccines and Infectious Diseases Research Group (GENVIP), Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Santiago de Compostela, Galicia, Spain; WHO Collaborating Centre for Vaccine Safety, Santiago de Compostela, Galicia, Spain; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain; Translational Pediatrics and Infectious Diseases, Hospital Clínico Universitario de Santiago (SERGAS) and University of Santiago de Compostela (USC), Santiago de Compostela, Galicia, Spain.<br /><searchLink fieldCode="AU" term="%22Begier+E%22">Begier E</searchLink>; Pfizer, New York, NY.<br /><searchLink fieldCode="AU" term="%22Biering-Sørensen+T%22">Biering-Sørensen T</searchLink>; Department of Cardiology, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark; Center for Translational Cardiology and Pragmatic Randomized Trials, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Steno Diabetes Center Copenhagen, Copenhagen, Denmark. Electronic address: tor.biering@gmail.com. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220370465%22">American heart journal</searchLink> [Am Heart J] 2026 Oct; Vol. 300, pp. 107497. <i>Date of Electronic Publication: </i>2026 Jun 01. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Pragmatic Clinical Trial; Randomized Controlled Trial – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Mosby%22">Mosby </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0370465 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1097-6744 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200028703%22">00028703 </searchLink><i>NLM ISO Abbreviation: </i>Am Heart J <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42219049 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.ahj.2026.107497 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 107497 Titles: – TitleFull: A pragmatic randomized trial to evaluate the vaccine effectiveness of bivalent RSV prefusion F vaccine for preventing RSV hospitalizations in adults (DAN-RSV): Trial design update. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Lassen MCH – PersonEntity: Name: NameFull: Christensen SH – PersonEntity: Name: NameFull: Johansen ND – PersonEntity: Name: NameFull: Yafasov M – PersonEntity: Name: NameFull: Pareek M – PersonEntity: Name: NameFull: Rudolph AE – PersonEntity: Name: NameFull: Tenreiro-Sánchez CR – PersonEntity: Name: NameFull: Skaarup KG – PersonEntity: Name: NameFull: Modin D – PersonEntity: Name: NameFull: Claggett BL – PersonEntity: Name: NameFull: Larsen CS – PersonEntity: Name: NameFull: Larsen L – PersonEntity: Name: NameFull: Wiese L – PersonEntity: Name: NameFull: Dalager-Pedersen M – PersonEntity: Name: NameFull: Lindholm MG – PersonEntity: Name: NameFull: Køber L – PersonEntity: Name: NameFull: Solomon SD – PersonEntity: Name: NameFull: Jensen JUS – PersonEntity: Name: NameFull: Martel CJ – PersonEntity: Name: NameFull: Aliabadi N – PersonEntity: Name: NameFull: Schwarz C – PersonEntity: Name: NameFull: Skovdal M – PersonEntity: Name: NameFull: Zhang P – PersonEntity: Name: NameFull: López-Gómez V – PersonEntity: Name: NameFull: Welsh S – PersonEntity: Name: NameFull: Gessner BD – PersonEntity: Name: NameFull: Martinón-Torres F – PersonEntity: Name: NameFull: Begier E – PersonEntity: Name: NameFull: Biering-Sørensen T IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 10 Text: 2026 Oct Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1097-6744 Numbering: – Type: volume Value: 300 Titles: – TitleFull: American heart journal Type: main |
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