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Ceralasertib Monotherapy in Patients with ATM-Altered Advanced Solid Tumors or Metastatic Castration-Resistant Prostate Cancer: Data from the Phase IIa PLANETTE Study.

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Title: Ceralasertib Monotherapy in Patients with ATM-Altered Advanced Solid Tumors or Metastatic Castration-Resistant Prostate Cancer: Data from the Phase IIa PLANETTE Study.
Authors: Aggarwal R; Division of Hematology/Oncology, University of California, San Francisco, California., Italiano A; Department of Medicine, Institut Bergonié, Bordeaux, France.; Faculty of Medicine, University of Bordeaux, Bordeaux, France., Domchek SM; Basser Center for BRCA, University of Pennsylvania, Philadelphia, Pennsylvania., Goodman O; Hematology/Oncology, Nevada Oncology Specialists, Las Vegas, Nevada., Postel-Vinay S; Drug Development Department, U981 INSERM Research Unit, Institut Gustave Roussy, Villejuif, France.; Cancer Institute, University College of London, London, United Kingdom., Garcia-Donas J; Gynecologic and Genitourinary Tumors, HM Hospitales - Centro Integral Oncológico HM Clara Campal, Madrid, Spain., Dorff T; Genitourinary Disease Program, City of Hope Comprehensive Cancer Center, Duarte, California., Reichert ZR; University of Michigan, Rogel Comprehensive Cancer Center, Ann Arbor, Michigan., Vinceneux A; Medical Oncology, Centre Léon Bérard, Lyon, France., Shore N; START Carolinas/Carolina Urologic Research Center, Myrtle Beach, South Carolina., Marshall CH; Oncology, Johns Hopkins University, Baltimore, Maryland., Armenia J; Oncology Data Science, AstraZeneca, Cambridge, United Kingdom., Parr G; Oncology Early Development Clinical, AstraZeneca, Cambridge, United Kingdom., Kmieciak A; Clinical Pharmacology and Quantitative Pharmacology, AstraZeneca, Cambridge, United Kingdom., Lukashchuk N; Translational Medicine, AstraZeneca, Cambridge, United Kingdom., Murina O; Translational Medicine, AstraZeneca, Cambridge, United Kingdom., Slade D; Statistical Science, AstraZeneca, Cambridge, United Kingdom., Shah N; Oncology Early Development Clinical, AstraZeneca, Waltham, Massachusetts., Loembé B; Oncology Early Development Clinical, AstraZeneca, Cambridge, United Kingdom., Dean E; Oncology Early Development, AstraZeneca, Cambridge, United Kingdom., Sanai E; Oncology Early Development Clinical, AstraZeneca, Cambridge, United Kingdom., Abida W; Genitourinary Oncology Service, Memorial Sloan Kettering Cancer Center, New York, New York.
Source: Cancer research communications [Cancer Res Commun] 2026 Jul 01; Vol. 6 (7), pp. 1546-1556.
Publication Type: Journal Article; Clinical Trial, Phase II; Multicenter Study; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9918281580506676 Publication Model: Print Cited Medium: Internet ISSN: 2767-9764 (Electronic) Linking ISSN: 27679764 NLM ISO Abbreviation: Cancer Res Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Ceralasertib Monotherapy in Patients with ATM-Altered Advanced Solid Tumors or Metastatic Castration-Resistant Prostate Cancer: Data from the Phase IIa PLANETTE Study.
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  Data: <searchLink fieldCode="AU" term="%22Aggarwal+R%22">Aggarwal R</searchLink>; Division of Hematology/Oncology, University of California, San Francisco, California.<br /><searchLink fieldCode="AU" term="%22Italiano+A%22">Italiano A</searchLink>; Department of Medicine, Institut Bergonié, Bordeaux, France.; Faculty of Medicine, University of Bordeaux, Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Domchek+SM%22">Domchek SM</searchLink>; Basser Center for BRCA, University of Pennsylvania, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Goodman+O%22">Goodman O</searchLink>; Hematology/Oncology, Nevada Oncology Specialists, Las Vegas, Nevada.<br /><searchLink fieldCode="AU" term="%22Postel-Vinay+S%22">Postel-Vinay S</searchLink>; Drug Development Department, U981 INSERM Research Unit, Institut Gustave Roussy, Villejuif, France.; Cancer Institute, University College of London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Garcia-Donas+J%22">Garcia-Donas J</searchLink>; Gynecologic and Genitourinary Tumors, HM Hospitales - Centro Integral Oncológico HM Clara Campal, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Dorff+T%22">Dorff T</searchLink>; Genitourinary Disease Program, City of Hope Comprehensive Cancer Center, Duarte, California.<br /><searchLink fieldCode="AU" term="%22Reichert+ZR%22">Reichert ZR</searchLink>; University of Michigan, Rogel Comprehensive Cancer Center, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Vinceneux+A%22">Vinceneux A</searchLink>; Medical Oncology, Centre Léon Bérard, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Shore+N%22">Shore N</searchLink>; START Carolinas/Carolina Urologic Research Center, Myrtle Beach, South Carolina.<br /><searchLink fieldCode="AU" term="%22Marshall+CH%22">Marshall CH</searchLink>; Oncology, Johns Hopkins University, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Armenia+J%22">Armenia J</searchLink>; Oncology Data Science, AstraZeneca, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Parr+G%22">Parr G</searchLink>; Oncology Early Development Clinical, AstraZeneca, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Kmieciak+A%22">Kmieciak A</searchLink>; Clinical Pharmacology and Quantitative Pharmacology, AstraZeneca, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Lukashchuk+N%22">Lukashchuk N</searchLink>; Translational Medicine, AstraZeneca, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Murina+O%22">Murina O</searchLink>; Translational Medicine, AstraZeneca, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Slade+D%22">Slade D</searchLink>; Statistical Science, AstraZeneca, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Shah+N%22">Shah N</searchLink>; Oncology Early Development Clinical, AstraZeneca, Waltham, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Loembé+B%22">Loembé B</searchLink>; Oncology Early Development Clinical, AstraZeneca, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Dean+E%22">Dean E</searchLink>; Oncology Early Development, AstraZeneca, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Sanai+E%22">Sanai E</searchLink>; Oncology Early Development Clinical, AstraZeneca, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Abida+W%22">Abida W</searchLink>; Genitourinary Oncology Service, Memorial Sloan Kettering Cancer Center, New York, New York.
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  Data: <searchLink fieldCode="JN" term="%229918281580506676%22">Cancer research communications</searchLink> [Cancer Res Commun] 2026 Jul 01; Vol. 6 (7), pp. 1546-1556.
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  Data: Journal Article; Clinical Trial, Phase II; Multicenter Study; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+Cancer+Research%22">American Association for Cancer Research </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9918281580506676 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>2767-9764 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2227679764%22">27679764 </searchLink><i>NLM ISO Abbreviation: </i>Cancer Res Commun <i>Subsets: </i>MEDLINE
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              Text: 2026 Jul 01
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