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Beyond sequence similarity: toward function-based screening of nucleic acid synthesis.

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Title: Beyond sequence similarity: toward function-based screening of nucleic acid synthesis.
Authors: Abel GR Jr; Fourth Eon Bio, San Diego, CA, United States.; Johns Hopkins University Center for Health Security, Baltimore, MD, United States., Alexanian T; International Biosecurity and Biosafety Initiative for Science, Geneva, Switzerland., Bartling C; Battelle Memorial Institute, Columbus, OH, United States., Beal J; RTX BBN Technologies, Cambridge, MA, United States., Curtis S; Center for AI Standards and Innovation (CAISI), National Institute of Standards and Technology, Washington, DC, United States., Flyangolts K; Aclid, New York, NY, United States., Foner L; SecureDNA, Basel, Switzerland., Forry SP; Biosystems and Biomaterials Division, National Institute of Standards and Technology, Gaithersburg, MD, United States., Godbold GD; Signature Science LLC, Charlottesville, VA, United States., Horvitz E; Microsoft, Office of the Chief Scientific Officer, Redmond, WA, United States., Hu B; Bioscience Division, Los Alamos National Laboratory, Los Alamos, NM, United States., Hudson CM; The Align Foundation, Covina, CA, United States., Jagla C; RTX BBN Technologies, Cambridge, MA, United States., Lababidi R; International Biosecurity and Biosafety Initiative for Science, Geneva, Switzerland., Lin-Gibson S; Biosystems and Biomaterials Division, National Institute of Standards and Technology, Gaithersburg, MD, United States., Magalis BR; Department of Biochemistry and Molecular Genetics, University of Louisville, Louisville, KY, United States., Pannu J; Johns Hopkins University Center for Health Security, Baltimore, MD, United States., Rivera S; Engineering Biology Research Consortium, Emeryville, CA, United States., Ross D; Biosystems and Biomaterials Division, National Institute of Standards and Technology, Gaithersburg, MD, United States., Wittmann BJ; Microsoft, Office of the Chief Scientific Officer, Redmond, WA, United States., Diggans J; Twist Bioscience, South San Francisco, CA, United States.; International Gene Synthesis Consortium, Emeryville, CA, United States.
Source: Frontiers in bioengineering and biotechnology [Front Bioeng Biotechnol] 2026 May 14; Vol. 14, pp. 1832724. Date of Electronic Publication: 2026 May 14 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 101632513 Publication Model: eCollection Cited Medium: Print ISSN: 2296-4185 (Print) Linking ISSN: 22964185 NLM ISO Abbreviation: Front Bioeng Biotechnol Subsets: PubMed not MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Abel+GR+Jr%22">Abel GR Jr</searchLink>; Fourth Eon Bio, San Diego, CA, United States.; Johns Hopkins University Center for Health Security, Baltimore, MD, United States.<br /><searchLink fieldCode="AU" term="%22Alexanian+T%22">Alexanian T</searchLink>; International Biosecurity and Biosafety Initiative for Science, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Bartling+C%22">Bartling C</searchLink>; Battelle Memorial Institute, Columbus, OH, United States.<br /><searchLink fieldCode="AU" term="%22Beal+J%22">Beal J</searchLink>; RTX BBN Technologies, Cambridge, MA, United States.<br /><searchLink fieldCode="AU" term="%22Curtis+S%22">Curtis S</searchLink>; Center for AI Standards and Innovation (CAISI), National Institute of Standards and Technology, Washington, DC, United States.<br /><searchLink fieldCode="AU" term="%22Flyangolts+K%22">Flyangolts K</searchLink>; Aclid, New York, NY, United States.<br /><searchLink fieldCode="AU" term="%22Foner+L%22">Foner L</searchLink>; SecureDNA, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Forry+SP%22">Forry SP</searchLink>; Biosystems and Biomaterials Division, National Institute of Standards and Technology, Gaithersburg, MD, United States.<br /><searchLink fieldCode="AU" term="%22Godbold+GD%22">Godbold GD</searchLink>; Signature Science LLC, Charlottesville, VA, United States.<br /><searchLink fieldCode="AU" term="%22Horvitz+E%22">Horvitz E</searchLink>; Microsoft, Office of the Chief Scientific Officer, Redmond, WA, United States.<br /><searchLink fieldCode="AU" term="%22Hu+B%22">Hu B</searchLink>; Bioscience Division, Los Alamos National Laboratory, Los Alamos, NM, United States.<br /><searchLink fieldCode="AU" term="%22Hudson+CM%22">Hudson CM</searchLink>; The Align Foundation, Covina, CA, United States.<br /><searchLink fieldCode="AU" term="%22Jagla+C%22">Jagla C</searchLink>; RTX BBN Technologies, Cambridge, MA, United States.<br /><searchLink fieldCode="AU" term="%22Lababidi+R%22">Lababidi R</searchLink>; International Biosecurity and Biosafety Initiative for Science, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Lin-Gibson+S%22">Lin-Gibson S</searchLink>; Biosystems and Biomaterials Division, National Institute of Standards and Technology, Gaithersburg, MD, United States.<br /><searchLink fieldCode="AU" term="%22Magalis+BR%22">Magalis BR</searchLink>; Department of Biochemistry and Molecular Genetics, University of Louisville, Louisville, KY, United States.<br /><searchLink fieldCode="AU" term="%22Pannu+J%22">Pannu J</searchLink>; Johns Hopkins University Center for Health Security, Baltimore, MD, United States.<br /><searchLink fieldCode="AU" term="%22Rivera+S%22">Rivera S</searchLink>; Engineering Biology Research Consortium, Emeryville, CA, United States.<br /><searchLink fieldCode="AU" term="%22Ross+D%22">Ross D</searchLink>; Biosystems and Biomaterials Division, National Institute of Standards and Technology, Gaithersburg, MD, United States.<br /><searchLink fieldCode="AU" term="%22Wittmann+BJ%22">Wittmann BJ</searchLink>; Microsoft, Office of the Chief Scientific Officer, Redmond, WA, United States.<br /><searchLink fieldCode="AU" term="%22Diggans+J%22">Diggans J</searchLink>; Twist Bioscience, South San Francisco, CA, United States.; International Gene Synthesis Consortium, Emeryville, CA, United States.
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  Data: <searchLink fieldCode="JN" term="%22101632513%22">Frontiers in bioengineering and biotechnology</searchLink> [Front Bioeng Biotechnol] 2026 May 14; Vol. 14, pp. 1832724. <i>Date of Electronic Publication: </i>2026 May 14 (<i>Print Publication: </i>2026).
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