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High-Throughput Reactive Desorption Electrospray Ionization Mass Spectrometry for Targeted Derivatization and Analysis of Poorly Ionized Small Molecules.

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Title: High-Throughput Reactive Desorption Electrospray Ionization Mass Spectrometry for Targeted Derivatization and Analysis of Poorly Ionized Small Molecules.
Authors: Feng Y; Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, United States.; Bindley Bioscience Center, Purdue University, West Lafayette, Indiana 47907, United States., Chen K; Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, United States., Huang KH; Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, United States., Caruso JV; Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, United States., Welch CJ; Indiana Consortium for Analytical Science and Engineering, Indianapolis, Indiana 46202, United States., Cooks RG; Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, United States.; Bindley Bioscience Center, Purdue University, West Lafayette, Indiana 47907, United States.; Purdue Institute for Cancer Research, Purdue University, West Lafayette, Indiana 47907, United States., Ferreira CR; Bindley Bioscience Center, Purdue University, West Lafayette, Indiana 47907, United States.; Department of Food Science, Purdue University, West Lafayette, Indiana 47907, United States., Morato NM; Purdue Institute for Cancer Research, Purdue University, West Lafayette, Indiana 47907, United States.
Source: Analytical chemistry [Anal Chem] 2026 Jun 16; Vol. 98 (23), pp. 16962-16970. Date of Electronic Publication: 2026 Jun 01.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6882 (Electronic) Linking ISSN: 00032700 NLM ISO Abbreviation: Anal Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: High-Throughput Reactive Desorption Electrospray Ionization Mass Spectrometry for Targeted Derivatization and Analysis of Poorly Ionized Small Molecules.
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  Data: <searchLink fieldCode="AU" term="%22Feng+Y%22">Feng Y</searchLink>; Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, United States.; Bindley Bioscience Center, Purdue University, West Lafayette, Indiana 47907, United States.<br /><searchLink fieldCode="AU" term="%22Chen+K%22">Chen K</searchLink>; Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, United States.<br /><searchLink fieldCode="AU" term="%22Huang+KH%22">Huang KH</searchLink>; Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, United States.<br /><searchLink fieldCode="AU" term="%22Caruso+JV%22">Caruso JV</searchLink>; Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, United States.<br /><searchLink fieldCode="AU" term="%22Welch+CJ%22">Welch CJ</searchLink>; Indiana Consortium for Analytical Science and Engineering, Indianapolis, Indiana 46202, United States.<br /><searchLink fieldCode="AU" term="%22Cooks+RG%22">Cooks RG</searchLink>; Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, United States.; Bindley Bioscience Center, Purdue University, West Lafayette, Indiana 47907, United States.; Purdue Institute for Cancer Research, Purdue University, West Lafayette, Indiana 47907, United States.<br /><searchLink fieldCode="AU" term="%22Ferreira+CR%22">Ferreira CR</searchLink>; Bindley Bioscience Center, Purdue University, West Lafayette, Indiana 47907, United States.; Department of Food Science, Purdue University, West Lafayette, Indiana 47907, United States.<br /><searchLink fieldCode="AU" term="%22Morato+NM%22">Morato NM</searchLink>; Purdue Institute for Cancer Research, Purdue University, West Lafayette, Indiana 47907, United States.
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  Data: <searchLink fieldCode="JN" term="%220370536%22">Analytical chemistry</searchLink> [Anal Chem] 2026 Jun 16; Vol. 98 (23), pp. 16962-16970. <i>Date of Electronic Publication: </i>2026 Jun 01.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0370536 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1520-6882 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200032700%22">00032700 </searchLink><i>NLM ISO Abbreviation: </i>Anal Chem <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1021/acs.analchem.6c00291
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      – Code: eng
        Text: English
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        StartPage: 16962
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      – TitleFull: High-Throughput Reactive Desorption Electrospray Ionization Mass Spectrometry for Targeted Derivatization and Analysis of Poorly Ionized Small Molecules.
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              Text: 2026 Jun 16
              Type: published
              Y: 2026
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