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Pyrazolo-quinolinone suppresses epithelial-mesenchymal transition by targeting the CXCR4/NF-κB axis in human pancreatic cancer cells.

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Title: Pyrazolo-quinolinone suppresses epithelial-mesenchymal transition by targeting the CXCR4/NF-κB axis in human pancreatic cancer cells.
Authors: Gowada D; Department of Studies in Chemistry, University of Mysore, Manasagangotri, Mysore, Karnataka 570006, India. Electronic address: darshinigowdabelur55@gmail.com., Yoon B; Department of Science in Korean Medicine, Kyung Hee University, 24 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea. Electronic address: bcdii08@khu.ac.kr., Jung YY; Department of Science in Korean Medicine, Kyung Hee University, 24 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea. Electronic address: ve449@naver.com., Harsha KB; Department of Studies in Chemistry, University of Mysore, Manasagangotri, Mysore, Karnataka 570006, India. Electronic address: shanthaharsha@gmail.com., Mohan CD; Systems Toxicology Group, Food, Drug & Chemical, Environment and Systems Toxicology (FEST) Division, CSIR-Indian Institute of Toxicology Research, Vishvigyan Bhawan, 31, Mahatma Gandhi Marg, Lucknow, Uttar Pradesh 226 001, India; Academy of Scientific and Innovative Research, Ghaziabad, Uttar Pradesh 201002, India. Electronic address: cd.mohan@yahoo.com., Um JY; Department of Science in Korean Medicine, Kyung Hee University, 24 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea; Kyung Hee Institute of Convergence Korean Medicine, Kyung Hee University, 24 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea. Electronic address: jyum@khu.ac.kr., Rangappa KS; Department of Studies in Chemistry, University of Mysore, Manasagangotri, Mysore, Karnataka 570006, India; Institution of Excellence, Vijnana Bhavan, University of Mysore, Manasagangotri, Mysore, Karnataka 570006, India. Electronic address: rangappaks@ioe.uni-mysore.ac.in., Ahn KS; Department of Science in Korean Medicine, Kyung Hee University, 24 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea; Kyung Hee Institute of Convergence Korean Medicine, Kyung Hee University, 24 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea. Electronic address: ksahn@khu.ac.kr.
Source: Pathology, research and practice [Pathol Res Pract] 2026 May 30; Vol. 286, pp. 156547. Date of Electronic Publication: 2026 May 30.
Publication Type: Journal Article
Journal Info: Publisher: Gustav Fischer Verlag Country of Publication: Germany NLM ID: 7806109 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-0631 (Electronic) Linking ISSN: 03440338 NLM ISO Abbreviation: Pathol Res Pract Subsets: MEDLINE
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  Data: Pyrazolo-quinolinone suppresses epithelial-mesenchymal transition by targeting the CXCR4/NF-κB axis in human pancreatic cancer cells.
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  Data: <searchLink fieldCode="AU" term="%22Gowada+D%22">Gowada D</searchLink>; Department of Studies in Chemistry, University of Mysore, Manasagangotri, Mysore, Karnataka 570006, India. Electronic address: darshinigowdabelur55@gmail.com.<br /><searchLink fieldCode="AU" term="%22Yoon+B%22">Yoon B</searchLink>; Department of Science in Korean Medicine, Kyung Hee University, 24 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea. Electronic address: bcdii08@khu.ac.kr.<br /><searchLink fieldCode="AU" term="%22Jung+YY%22">Jung YY</searchLink>; Department of Science in Korean Medicine, Kyung Hee University, 24 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea. Electronic address: ve449@naver.com.<br /><searchLink fieldCode="AU" term="%22Harsha+KB%22">Harsha KB</searchLink>; Department of Studies in Chemistry, University of Mysore, Manasagangotri, Mysore, Karnataka 570006, India. Electronic address: shanthaharsha@gmail.com.<br /><searchLink fieldCode="AU" term="%22Mohan+CD%22">Mohan CD</searchLink>; Systems Toxicology Group, Food, Drug & Chemical, Environment and Systems Toxicology (FEST) Division, CSIR-Indian Institute of Toxicology Research, Vishvigyan Bhawan, 31, Mahatma Gandhi Marg, Lucknow, Uttar Pradesh 226 001, India; Academy of Scientific and Innovative Research, Ghaziabad, Uttar Pradesh 201002, India. Electronic address: cd.mohan@yahoo.com.<br /><searchLink fieldCode="AU" term="%22Um+JY%22">Um JY</searchLink>; Department of Science in Korean Medicine, Kyung Hee University, 24 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea; Kyung Hee Institute of Convergence Korean Medicine, Kyung Hee University, 24 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea. Electronic address: jyum@khu.ac.kr.<br /><searchLink fieldCode="AU" term="%22Rangappa+KS%22">Rangappa KS</searchLink>; Department of Studies in Chemistry, University of Mysore, Manasagangotri, Mysore, Karnataka 570006, India; Institution of Excellence, Vijnana Bhavan, University of Mysore, Manasagangotri, Mysore, Karnataka 570006, India. Electronic address: rangappaks@ioe.uni-mysore.ac.in.<br /><searchLink fieldCode="AU" term="%22Ahn+KS%22">Ahn KS</searchLink>; Department of Science in Korean Medicine, Kyung Hee University, 24 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea; Kyung Hee Institute of Convergence Korean Medicine, Kyung Hee University, 24 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Republic of Korea. Electronic address: ksahn@khu.ac.kr.
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